Zobrazeno 1 - 10
of 7 063
pro vyhledávání: '"pan‐cancer"'
Autor:
Fatemeh Maghool, Parisa Kadkhodaei Elyaderani, Samaneh Mohammadzadeh, Amir Hosseini, Aida Heidari, Pouria Samadi
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Our study investigates the multifaceted role of the gene SLC30A6 across 33 distinct cancer types. Understanding the function and impact of SLC30A6 in cancer biology is crucial, as previous studies have hinted at its aberrant expre
Externí odkaz:
https://doaj.org/article/d6da89bf26b445268253589c0d891084
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Background GNL2, a nuclear protein, is involved in ribosome production and cell cycle regulation. However, its expression and function in different types of tumors are not well understood. Comprehensive studies across multiple cancer types a
Externí odkaz:
https://doaj.org/article/b60bfa1f13584ddeb59f73878049e020
Autor:
Enzhi Yin, Chengming Liu, Yuxin Yao, Yuejun Luo, Yaning Yang, Xiaoya Tang, Sufei Zheng, Linyan Tian, Jie He
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-20 (2024)
Abstract Cancer remains a leading cause of mortality globally, highlighting the need for novel biomarkers to enhance prognosis and therapeutic strategies. Pleckstrin-2 (PLEK2), a member of the pleckstrin family, has been implicated in processes criti
Externí odkaz:
https://doaj.org/article/6f20abdd31a0413bb914f9d735efc406
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Immunotherapy has emerged as a vital component in the contemporary landscape of cancer treatment. Recent studies have indicated that CEP55 plays an oncogenic role; however, its specific mechanisms in promoting tumor proliferation and its pot
Externí odkaz:
https://doaj.org/article/452b6cae713c46a299a151bf4057d546
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract dCTP pyrophosphatase 1 (DCTPP1) is widely expressed in tumors and the immune system and plays a critical role in human cancer progression. However, multi-omics characterization of DCTPP1 and its role in prognosis and immune microenvironment
Externí odkaz:
https://doaj.org/article/11d73fcdec5644f7af5fd0686269b899
Autor:
Shushu Qian, Huafeng Liu, Min Zhang, Li Zhang, Yunlan Dai, Xiangming Ye, Wanshun Wen, Ruidong Cheng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Despite improvements in treatment in recent years, patients with lung adenocarcinoma (LUAD) still face poor prognoses. In this study, we elucidated the potential role of NOP58 ribonucleoprotein in pan-cancer and validated its oncogenic signi
Externí odkaz:
https://doaj.org/article/e1f8f4a581f6448aa6769f3b8d26bdf3
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background SLIT and NTRK-like protein 2 (SLITRK2) encodes a transmembrane protein that regulates neurite outgrowth. Some studies have demonstrated that SLITRK2 overexpressed in glioma. But the expression pattern, prognostic value and immunol
Externí odkaz:
https://doaj.org/article/3f7a3b8034e44a40ac85fc27bb183b62
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract The present study investigated the Zinc finger BED-type containing 3 (ZBED3) mRNA expression levels, diagnostic and prognostic values, co-expressed and differentially expressed genes, immune infiltration, and functional enrichment analysis i
Externí odkaz:
https://doaj.org/article/a97b3afb8bb942b096f2d6e71cd3fcac
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract A pan-cancer analysis summarizing the overall changes in mRNA and protein stability of ADM9, as well as its oncogenic function on immune cell line modulation and checkpoints within the tumor microenvironment (TME), is lacking, despite the fa
Externí odkaz:
https://doaj.org/article/1723da08c0fe4a2491ab4d724cce0e07
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Studies have underscored the pivotal role of metastasis-associated protein 3 (MTA3) as a cancer regulator, yet its potential as a drug target across cancers necessitates comprehensive evaluation. In this study, we analyzed MTA3 expression pr
Externí odkaz:
https://doaj.org/article/85a66d2ead824356bfa3cb7d52b664b0