Zobrazeno 1 - 10
of 3 669
pro vyhledávání: '"pERK"'
Autor:
Michela Luciano, Helene Sieberer, Peter W. Krenn, Hieu-Hoa Dang, Julia Vetter, Theresa Neuper, Diana Amend, Constantin Blöchl, Christian X. Weichenberger, Anna Eglseer, Michael S. Unger, Ancuela Andosch, Philip Steiner, Daniel Neureiter, Renate Bauer, Laura Hummer, Suzana Tesanovic, Stephanie Binder, Dominik P. Elmer, Helen Strandt, Susanne Schaller, Dirk Strunk, Lisa Pleyer, Richard Greil, Stephan Winkler, Tanja N. Hartmann, Dirk Schmidt-Arras, Christian G. Huber, Fritz Aberger, Jutta Horejs-Hoeck
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Acute myeloid leukemia (AML) is characterized by the abnormal proliferation of myeloid precursor cells and presents significant challenges in treatment due to its heterogeneity. Recently, the NLRP3 inflammasome has emerged as a po
Externí odkaz:
https://doaj.org/article/4d77e7ab0fdf4883bc818ffc7dd4f0d8
Publikováno v:
Transactions on Cryptographic Hardware and Embedded Systems, Vol 2024, Iss 4 (2024)
One category of the digital signatures submitted to the NIST Post-Quantum Cryptography Standardization Process for Additional Digital Signature Schemes comprises proposals constructed leveraging the MPC-in-the-Head (MPCitH) paradigm. Typically, this
Externí odkaz:
https://doaj.org/article/de884161acae442ba917ba6b5c3794d3
Publikováno v:
International Journal of Managerial Finance, 2023, Vol. 20, Issue 3, pp. 794-820.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/IJMF-09-2021-0458
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4286-4308 (2024)
Coronaviruses represent a significant class of viruses that affect both animals and humans. Their replication cycle is strongly associated with the endoplasmic reticulum (ER), which, upon virus invasion, triggers ER stress responses. The activation o
Externí odkaz:
https://doaj.org/article/9adc431be66142aab72337b0d0667a3f
Autor:
Hideshi Ikemoto, Naoki Adachi, Takayuki Okumo, Oyunchimeg Chuluunbat, Tadashi Hisamitsu, Masataka Sunagawa
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 5, Pp 456-466 (2024)
Abstract Transcutaneous electrical nerve stimulation (TENS) activates various pathways to induce antinociceptive effects, based on the frequencies used. This study evaluates the preemptive analgesic effects and their duration of low‐ (LT: 4 Hz) and
Externí odkaz:
https://doaj.org/article/5ecb01a0e46540a59652d49445698625
Autor:
Mengnan Ding, Yarong Lu, Qing Wen, Chen Xing, Xin Huang, Yifan Zhang, Wei Wang, Chongchong Zhang, Min Zhang, Fanfei Meng, Kun Liu, Guangchao Liu, Lun Song
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Ambient air temperature is a key factor affecting human health. Female reproductive disorders are representative health risk events under low temperature. However, the mechanism involving in cold-induced female reproductive disorders remains
Externí odkaz:
https://doaj.org/article/09fe04abcf07475c954be1b0eecc56ad
Publikováno v:
Regulatory Mechanisms in Biosystems, Vol 15, Iss 2, Pp 367-373 (2024)
Endoplasmic reticulum stress (ER stress) activates the unfolded protein response (UPR) as a defense mechanism for maintaining cellular vital activity. Data on interaction between pathways of UPR-sensors, their role and participation in the recovery o
Externí odkaz:
https://doaj.org/article/ae7d1bc9a9334e80be713605e34b015a
Akademický článek
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Autor:
Andrea Imhoff, Noreena L. Sweeney, Robert D. Bongard, Raulia Syrlybaeva, Ankan Gupta, Edgar Del Carpio, Marat R. Talipov, Costanza Garcia-Keller, Debbie C. Crans, Ramani Ramchandran, Daniel S. Sem
Publikováno v:
Frontiers in Chemical Biology, Vol 3 (2024)
Introduction: Dual specific phosphatases (DUSPs) are mitogen-activated protein kinase (MAPK) regulators, which also serve as drug targets for treating various vascular diseases. Previously, we have presented mechanistic characterizations of DUSP5 and
Externí odkaz:
https://doaj.org/article/aa4cabe9328a4a3eac7c09b8153c0873
Autor:
Tiancheng Hu, Yiping Liu, Jeremy Fleck, Cason King, Elaine Schalk, Zhenyu Zhang, Andrew Mehle, Judith A. Smith
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The double-stranded DNA (dsDNA) sensor STING has been increasingly implicated in responses to “sterile” endogenous threats and pathogens without nominal DNA or cyclic di-nucleotide stimuli. Previous work showed an endoplasmic reticulum (ER) stres
Externí odkaz:
https://doaj.org/article/9edb2198c6ea41b3861f589b52b66b8d