Zobrazeno 1 - 10
of 1 633
pro vyhledávání: '"p75 neurotrophin receptor"'
Autor:
Hyeyoon Eo, Jin Hee Kim, Hyeri Im, In Gyoung Ju, Eugene Huh, Rabin Pun, Dongyun Shin, Yunsook Lim, Myung Sook Oh
Publikováno v:
Journal of Functional Foods, Vol 113, Iss , Pp 106025- (2024)
The present study aimed to investigate the effect of 6-shogaol (6S) treatment on brain senescence. Mice were naturally aged until 25-month-old and treated with 10 mg/kg of 6S for a month. Behavioral tests were performed to measure locomotion and cogn
Externí odkaz:
https://doaj.org/article/72180f326e2c453c9c682b90a576200d
Autor:
Raquel Comaposada-Baró, Andrea Benito-Martínez, Juan Julian Escribano-Saiz, María Luisa Franco, Lorenzo Ceccarelli, Isabel Calatayud-Baselga, Helena Mira, Marçal Vilar
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Degeneration of basal forebrain cholinergic neurons (BFCNs) is a hallmark of Alzheimer’s disease (AD). However, few mouse models of AD recapitulate the neurodegeneration of the cholinergic system. The p75 neurotrophin receptor, p75NTR, has been ass
Externí odkaz:
https://doaj.org/article/b32bcd3bb77444a1a7f76966aae5d7b9
Publikováno v:
Animal Models and Experimental Medicine, Vol 6, Iss 1, Pp 3-9 (2023)
Abstract β‐Amyloid (Aβ) is a specific pathological hallmark of Alzheimer's disease (AD). Because of its neurotoxicity, AD patients exhibit multiple brain dysfunctions. Disease‐modifying therapy (DMT) is the central concept in the development of
Externí odkaz:
https://doaj.org/article/904ae21c376f47bc8ff17301c12751ca
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 12, Pp 2573-2581 (2023)
Axonal growth inhibitors are released during traumatic injuries to the adult mammalian central nervous system, including after spinal cord injury. These molecules accumulate at the injury site and form a highly inhibitory environment for axonal regen
Externí odkaz:
https://doaj.org/article/ae5e73cb4def4ba790cacadd90e265ec
Autor:
Hendrik Demuth, Shirin Hosseini, Henning Peter Düsedeau, Ildiko Rita Dunay, Martin Korte, Marta Zagrebelsky
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionAlzheimer’s disease (AD), is characterized by a gradual cognitive decline associated with the accumulation of Amyloid beta (Aβ)-oligomers, progressive neuronal degeneration and chronic neuroinflammation. Among the receptors shown to bi
Externí odkaz:
https://doaj.org/article/8d84cd6584694217a0859eaa54478439
Akademický článek
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Autor:
Dandan Zhang, Shengnan Zhao, Zhijie Zhang, Danfeng Xu, Di Lian, Jing Wu, Dake He, Kun Sun, Ling Li
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-22 (2021)
Abstract Background Streptococcus pneumoniae meningitis is a destructive central nervous system (CNS) infection with acute and long-term neurological disorders. Previous studies suggest that p75NTR signaling influences cell survival, apoptosis, and p
Externí odkaz:
https://doaj.org/article/2e31a59808e5424ab8ddbea6fd4f2884
Autor:
Hongyan Yuan, Bo Xie, Xia Yu, Cheng Lin, Meng Li, Yixin Zhang, Xuqiang Zou, Mingjie Lu, Manzhu Zhao, Xiujie Wen
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Objective: Tooth morphogenesis and the formation of hard tissues have been reported to be closely related to circadian rhythms. This study investigates the spatiotemporal expression and relationship of p75NTR with core clock genes, mineralization-rel
Externí odkaz:
https://doaj.org/article/9749ba27f1b344969125c2d6f193aa93
Autor:
Juan P Zanin, Wilma J Friedman
Publikováno v:
eLife, Vol 11 (2022)
Neuronal migration is one of the fundamental processes during brain development. Several neurodevelopmental disorders can be traced back to dysregulated migration. Although substantial efforts have been placed in identifying molecular signals that st
Externí odkaz:
https://doaj.org/article/0730206d734d4dbfab7830b9b296e39f
Autor:
Rina Fujii-Tezuka, Mika Ishige-Wada, Narihito Nagoshi, Hideyuki Okano, Hideo Mugishima, Shori Takahashi, Ichiro Morioka, Taro Matsumoto
Publikováno v:
Regenerative Therapy, Vol 16, Iss , Pp 1-11 (2021)
Introduction: The p75 neurotrophin receptor (p75NTR) is known as an efficient marker for the prospective isolation of mesenchymal stem cells (MSCs) and neural crest-derived stem cells (NCSCs). To date, there is quite limited information concerning p7
Externí odkaz:
https://doaj.org/article/79c5db32c2fb42c6b87655f6d81644a6