Zobrazeno 1 - 10
of 671
pro vyhledávání: '"p53 status"'
Autor:
Wang Hongxia, Yan Ruifang, Li Zhong, Wang Beiran, Jin Xingxing, Guo Zhenfang, Liu Wangyi, Zhang Meng, Wang Kaiyu, Guo Jinxia, Han Dongming
Publikováno v:
Radiology and Oncology, Vol 57, Iss 2, Pp 257-269 (2023)
The aim of the study was to investigate the value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and intravoxel incoherent motion (IVIM) in differentiating TP53-mutant from wild type, low-risk from non-low-risk early-stage endometr
Externí odkaz:
https://doaj.org/article/f805cef25e4e47cc94380a95450508ea
Publikováno v:
Cancers, Vol 16, Iss 5, p 921 (2024)
This study evaluated the magnetic resonance imaging (MRI) findings of endometrial cancer (EC) patients and identified differences based on risk group and molecular classification. The study involved a total of 175 EC patients. The MRI data were retro
Externí odkaz:
https://doaj.org/article/d849ebe7fec640ffaadb7e9e51b67696
Autor:
Leon F. McSwain, Kiran K. Parwani, Shubin W. Shahab, Dolores Hambardzumyan, Tobey J. MacDonald, Jennifer M. Spangle, Anna Marie Kenney
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Medulloblastoma (MB) is the most common malignant brain tumor in children with standard of care consisting of surgery, radiation, and chemotherapy. Recent molecular profiling led to the identification of four molecularly distinct MB subgroups – Win
Externí odkaz:
https://doaj.org/article/c595f4316e4c4748b7e37bfac2ab45da
Akademický článek
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Publikováno v:
Advances in Medical Sciences. 67(2):379-385
Purpose Human carcinoma cells with different p53 status exposed to a combination of bioactive substances, resveratrol and berberine, revealed different responses in cell viability via p53-dependant apoptosis pathway activation. Materials and methods
Publikováno v:
Journal of Medical pharmaceutical and allied sciences. 10:3421-3424
Glial tumors occupy approximately 70% of the spectrum of all brain tumors with astrocytoma’s being the most common primary. High grade glial tumors have a poor outcome with limited survival rate. To establish the correlation between p53 status and
Cancer Immunotherapy relies on harnessing a patient's immune system to fine-tune specific anti-tumor responses and ultimately eradicate cancer. Among diverse therapeutic approaches, oncolytic viruses (OVs) have emerged as a novel form of cancer immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1593::db83d263c8aeff2d80653f88f053bc35
http://hdl.handle.net/10138/342610
http://hdl.handle.net/10138/342610
Publikováno v:
Genes Dev
p53 is an important tumor suppressor, and the complexities of p53 function in regulating cancer cell behaviour are well established. Many cancers lose or express mutant forms of p53, with evidence that the type of alteration affecting p53 may differe
Autor:
Takeo Goto, Atsufumi Nagahama, Kentaro Naito, Kenji Ohata, Takehiro Uda, Hiroki Morisako, Kosuke Nakajo, Tsutomu Ichinose, Masakazu Yashiro, Toshiyuki Kawashima
Publikováno v:
Anticancer Research. 41:203-210
Background Meningioma is a common intracranial tumor originating from arachnoid cap cells. Meningiomas are generally benign tumors curable by one-time resection. However, some meningiomas regrow and invade into the dura mater, and thus frequently req
Publikováno v:
Journal of Oncology
Journal of Oncology, Vol 2020 (2020)
Journal of Oncology, Vol 2020 (2020)
Objective. To investigate the prognostic significance of HPV status in vulvar squamous cell carcinomas (VSCC) and to determine whether preoperative determination of p16 or p53 status would have clinical relevance. Methods. Patients treated for VSCC a