Coinhibition of activated p38 MAPKα and mTORC1 potentiates stemness maintenance of HSCs from SR1-expanded human cord blood CD34

Autor: Xiaoyi, Li, Xiao, Ma, Ying, Chen, Danyue, Peng, Huifang, Wang, Suhua, Chen, Yin, Xiao, Lei, Li, Hao, Zhou, Fanjun, Cheng, Yingdai, Gao, Jiwei, Chang, Tao, Cheng, Lingbo, Liu

Publikováno v: Stem Cells Translational Medicine

The stemness of ex vivo expanded hematopoietic stem cells (HSCs) is usually compromised by current methods. To explore the failure mechanism of stemness maintenance of human HSCs, which were expanded from human umbilical cord blood (hUCB) CD34+ cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::44faf644bff0e7b93b3da8d9e09be3de
https://pubmed.ncbi.nlm.nih.gov/32602209

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Anti-apoptotic phenotypes of cholestan-3β,5α,6β-triol-resistant human cholangiocytes: characteristics contributing to the genesis of cholangiocarcinoma.

Autor: Jusakul A; Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand; Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand; Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA; Department of Veterans Affairs Medical Center, Seattle, WA, USA., Loilome W, Namwat N, Techasen A, Kuver R, Ioannou GN, Savard C, Haigh WG, Yongvanit P

Publikováno v: The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2013 Nov; Vol. 138, pp. 368-75. Date of Electronic Publication: 2013 Aug 16.