Zobrazeno 1 - 10
of 13 377
pro vyhledávání: '"p38 mapk"'
Autor:
María-Milagros Rodríguez-Cano, María-Julia González-Gómez, Eva-María Monsalve, María-José M. Díaz-Guerra, Moustapha Kassem, Jorge Laborda, María-Luisa Nueda, Victoriano Baladrón
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-17 (2024)
Abstract Background C3H10T1/2 is a mesenchymal cell line capable of differentiating into osteoblasts, adipocytes and chondrocytes. The differentiation of these cells into osteoblasts is modulated by various transcription factors, such as RUNX2. Addit
Externí odkaz:
https://doaj.org/article/59d36de7aa4e4b6cadcd8748f02b433b
Autor:
Bin Zheng, Mengying Li, Enhong Lan, Wenting Ding, Lijiao Gao, Yue Tang, Xinyi Wu, Bing Zhang, Yali Zhang, Xiaona Zhu, Hui Zhang
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Acute lung injury (ALI) is a serious acute respiratory disease that can cause alveolar-capillary barrier disruption and pulmonary edema, respiratory failure and multiple organ dysfunction syndrome. However, there is no effective drugs in cli
Externí odkaz:
https://doaj.org/article/aafe4882ad7a48a5a9920420485b4b8b
Autor:
Akie Ikushima, Takuya Ishimura, Keita P. Mori, Hiroyuki Yamada, Sayaka Sugioka, Akira Ishii, Naohiro Toda, Shoko Ohno, Yukiko Kato, Takaya Handa, Motoko Yanagita, Hideki Yokoi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract One of the most common causes of peritoneal dialysis withdrawal is ultrafiltration failure which is characterized by peritoneal membrane thickening and fibrosis. Although previous studies have demonstrated the inhibitory effect of p38 MAPK i
Externí odkaz:
https://doaj.org/article/ee4f9235bcb34ba88efba556ea452fdc
Autor:
M.G. SHURYGIN, S.L. BOGORODSKAYA, E.E. CHEPURNYKH, L.V. RODIONOVA, L.G. SAMOYLOVA, I.A. SHURYGINA
Publikováno v:
Паёми Сино, Vol 26, Iss 3, Pp 417-426 (2024)
Objective: Study the proteolytic activity during experimental peritonitis using Seroguard® as a local anti-inflammatory agent Methods: The experiment involved male Wistar rats aged 6 months. The researchers induced experimental peritonitis in the
Externí odkaz:
https://doaj.org/article/970adf8e87e6478aab0913f3ced6d220
Publikováno v:
Radiation Medicine and Protection, Vol 5, Iss 3, Pp 161-164 (2024)
Skin Exposure of skin to ionizing radiation can induce acute or chronic biological effects, resulting in radiation-induced skin injury (RSI). Premature cellular senescence, caused by oxidative stress and/or DNA damage from chemical or physical agents
Externí odkaz:
https://doaj.org/article/09b0383baea74cf49b3eac61acb78a28
Autor:
Jintang Li, Hang Gao, Ping Wang, Chao Sun, Zhilin Wei, Xingcheng Yi, Shuyuan Yu, Yanan Zhang, Shuqiang Li
Publikováno v:
Alexandria Engineering Journal, Vol 103, Iss , Pp 222-236 (2024)
Plumbagin (PLB), a naphthoquinone compound, has been proven to have anti-cancer properties in different types of cancers. However, the anti-tumor actions as well as molecular processes in osteosarcoma (OS) remain unclear. This study investigates the
Externí odkaz:
https://doaj.org/article/3b6a0791aa4845bb95fc0b61a2a961db
Autor:
Jaw Long Sun, Young Jin Kim, Wonjun Cho, Sung Su Park, A.M. Abd El-Aty, Enas H. Mobarak, Tae Woo Jung, Ji Hoon Jeong
Publikováno v:
Obesity Facts, Pp 1-11 (2024)
Introduction: Previous research has shown that an aqueous extract of Humulus japonicus (EH) can ameliorate hypertension, nonalcoholic fatty liver disease, and oxidative stress in adipocytes by activating the thermogenic pathway. However, the effects
Externí odkaz:
https://doaj.org/article/b5e2bf499b3e4e9a9271e4dfa3c09570
Autor:
Arun Kumar, Manti Kumar Saha, Vipin Kumar, Anupam Bhattacharya, Sagar Barge, Ashis K. Mukherjee, Mohan C. Kalita, Mojibur R. Khan
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-26 (2024)
Abstract Background Proteostasis is a critical aging hallmark responsible for removing damaged or misfolded proteins and their aggregates by improving proteasomal degradation through the autophagy-lysosome pathway (ALP) and the ubiquitin–proteasome
Externí odkaz:
https://doaj.org/article/aa0932f2118e495c882362803d5f1708
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 5039-5056 (2024)
Xuan Wang,1,* Hanjie Yu,2,* Yunheng Zhang,3,* Xin Chang,1 Chengyi Liu,1 Xiaodong Wen,1 Feng Tian,1 Yi Li1 1Department of Foot and Ankle Surgery, Honghui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China
Externí odkaz:
https://doaj.org/article/82c9c8a424314080bd83c23916f74d85
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 7032-7047 (2024)
HBeAg is a non-structural, secreted protein of hepatitis B virus (HBV). Its p25 precursor is post-translationally modified in the endoplasmic reticulum. The G1862T precore mutation leads to the accumulation of P25 in the endoplasmic reticulum and act
Externí odkaz:
https://doaj.org/article/48be2fdf14d24f99940ec619e6a77e40