Zobrazeno 1 - 10
of 430
pro vyhledávání: '"p38 MAPK pathway"'
Publikováno v:
Poultry Science, Vol 103, Iss 11, Pp 104204- (2024)
ABSTRACT: Fatty liver disease in laying hens, characterized by excessive lipid accumulation in hepatocytes, poses significant challenges to poultry health and production efficiency. In this study, we investigated the therapeutic potential of epigallo
Externí odkaz:
https://doaj.org/article/9d7a718c3ab74e1b8081a7d4e5f59d79
Autor:
Yi Tian, Xiao Xiao, Weiliang Liu, Shanqing Cheng, Na Qian, Ling Wang, Yang Liu, Rong Ai, Xiaoping Zhu
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Background Autism spectrum disorder (ASD) encompasses a diverse range of neurodevelopmental disorders, but the precise underlying pathogenesis remains elusive. This study aim to explore the potential mechanism of TREM2 in regulating microgli
Externí odkaz:
https://doaj.org/article/7a826b1cbf2e4f079417e2edf65d4e6f
Autor:
Chong Wang, Ying Shi, Wen Gu, Chao Wang, Yongjun Xu, Li Li, Lixia Zhang, Shaoping Zhang, Hong Zhi, Hongjie Ruan, Jian Kong, Lian Duan, Song Tang
Publikováno v:
Environmental Sciences Europe, Vol 35, Iss 1, Pp 1-12 (2023)
Abstract We conducted a comprehensive investigation into the protective roles of boron (B) against trichloroacetic acid (TCA)-induced hepatotoxicity by assessing TCA exposure in vivo and exploring the potential mechanisms by which B protects against
Externí odkaz:
https://doaj.org/article/68b21e6b7b78477585a034499a2859c5
Autor:
Xingmin Zhang, Zilin Zhang, Xiaosong Zou, Yongjie Wang, Jinwei Qi, Song Han, Jingguo Xin, Zhi Zheng, Lin Wei, Tianhui Zhang, Shaokun Zhang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Intervertebral disc (IVD) degeneration (IDD) is a worldwide spinal degenerative disease. Low back pain (LBP) is frequently caused by a variety of conditions brought on by IDD, including IVD herniation and spinal stenosis, etc. These conditions bring
Externí odkaz:
https://doaj.org/article/75a8fc6c9e464d38bcf5669d368a9150
Transcriptomic Analysis of PDCoV-Infected HIEC-6 Cells and Enrichment Pathways PI3K-Akt and P38 MAPK
Autor:
Yuhang Jiang, Guoqing Zhang, Letian Li, Maopeng Wang, Jing Chen, Pengfei Hao, Zihan Gao, Jiayi Hao, Chang Li, Ningyi Jin
Publikováno v:
Viruses, Vol 16, Iss 4, p 579 (2024)
Porcine Deltacoronavirus (PDCoV) is a newly identified coronavirus that causes severe intestinal lesions in piglets. However, the understanding of how PDCoV interacts with human hosts is limited. In this study, we aimed to investigate the interaction
Externí odkaz:
https://doaj.org/article/9bd1a195c6df4e14acfb38ea7474090e
Publikováno v:
Brain Sciences, Vol 14, Iss 4, p 380 (2024)
The analgesic efficacy of acupuncture has been widely recognized. However, the mechanism by which manual acupuncture-generated mechanical stimuli translate into biological signals remains unclear. This study employed a CFA-induced inflammatory pain r
Externí odkaz:
https://doaj.org/article/a8d3d62ba17245b0ab48e7a3f7b48f7f
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Background Bone has important functions in the body. Several researchers have reported that the polysaccharides and lipopolysaccharide derived from microbes can promote osteogenic differentiation of stem cells. Enterococcus faecium, a lactic
Externí odkaz:
https://doaj.org/article/2765eef956c24707808a7bc43d0815b5
Autor:
Jing Luo, Qiang Gao, Hailong Qiu, Shuai Zhang, Wanwan Zou, Ping Wang, Lishi Zhou, Lingling Liu, Feng Xu, Xiaohua Li, Bin Lin, Rong Zeng, Daoheng Sun, Jianzheng Cen, Jian Zhuang
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 2, p 49 (2024)
Background: Myogenin is well known as a crucial transcription factor in skeletal muscle development, yet its other biological functions remain unexplored. Previous research showed that myogenin suppresses apoptosis induced by angiotensin II in human
Externí odkaz:
https://doaj.org/article/c474fe2199ad4fb0a0196b49dd73f953
Autor:
Zhaoling Sun, Xiaojing Zhang, Yiming Dong, Yichang Liu, Chuan Wang, Yingmin Li, Chunling Ma, Guangming Xu, Songjun Wang, Chenteng Yang, Guozhong Zhang, Bin Cong
Publikováno v:
Brain Sciences, Vol 14, Iss 2, p 161 (2024)
The amygdala is a core region in the limbic system that is highly sensitive to stress. Astrocytes are key players in stress disorders such as anxiety and depression. However, the effects of stress on the morphology and function of amygdala astrocytes
Externí odkaz:
https://doaj.org/article/74f833ac0d1f46f6902bb08c3f2d0e55
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