Zobrazeno 1 - 10
of 515
pro vyhledávání: '"p120‐catenin"'
Autor:
Xiong Tianhua, Wang Dinghui, Yang Huiping, Liu Bin, Li Yingrui, Yu Wenlong, Wang Jing, She Qiang
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 717-729 (2024)
The epicardium is integral to cardiac development and facilitates endogenous heart regeneration and repair. While miR-194-3p is associated with cellular migration and invasion, its impact on epicardial cells remains uncharted. In this work we use gai
Externí odkaz:
https://doaj.org/article/d48b5456f35444ebac12be2ff40dfd49
Autor:
Rubén A. Bartolomé, Laura Pintado-Berninches, Ángela Martín-Regalado, Javier Robles, Tania Calvo-López, Marina Ortega-Zapero, Celia Llorente-Sáez, Issam Boukich, María Jesús Fernandez-Aceñero, J. Ignacio Casal
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Cadherin-17 (CDH17), a marker of differentiation in intestinal cells, binds and activates α2β1 integrin to promote cell adhesion and proliferation in colorectal cancer (CRC) metastasis. Furthermore, CDH17 associates with p120- a
Externí odkaz:
https://doaj.org/article/c966be1e7f0f4d22a3aa627c32f73981
Degradation of p0071 and p120-catenin during adherens junction disassembly by Leptospira interrogans
Autor:
Romina Tokumon, Isabel Sebastián, Bruno M. Humbel, Nobuhiko Okura, Hidenori Yamanaka, Tetsu Yamashiro, Claudia Toma
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Leptospira interrogans disseminates hematogenously to reach the target organs by disrupting epithelial adherens junctions (AJs), thus causing leptospirosis, which is a globally neglected zoonotic disease. L. interrogans induces E-cadherin (E-cad) end
Externí odkaz:
https://doaj.org/article/e4320b2e80e44ffe929bf3cdaa0e5a01
Akademický článek
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Akademický článek
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Autor:
Matthias Christgen, Leonie Donata Kandt, Wiebke Antonopoulos, Stephan Bartels, Mieke R VanBockstal, Martin Bredt, Maria Jose Brito, Henriette Christgen, Cecile Colpaert, Bálint Cserni, Gábor Cserni, Maximilian E Daemmrich, Raihanatou Danebrock, Franceska Dedeurwaerdere, Carolien HM vanDeurzen, Ramona Erber, Christine Fathke, Henning Feist, Maryse Fiche, Claudia Aura Gonzalez, Natalie D terHoeve, Loes Kooreman, Till Krech, Glen Kristiansen, Janina Kulka, Florian Laenger, Marcel Lafos, Ulrich Lehmann, Maria Dolores Martin‐Martinez, Sophie Mueller, Enrico Pelz, Mieke Raap, Alberto Ravarino, Tanja Reineke‐Plaass, Nora Schaumann, Anne‐Marie Schelfhout, Maxim DeSchepper, Jerome Schlue, Koen Van de Vijver, Wim Waelput, Axel Wellmann, Monika Graeser, Oleg Gluz, Sherko Kuemmel, Ulrike Nitz, Nadia Harbeck, Christine Desmedt, Giuseppe Floris, Patrick WB Derksen, Paul J vanDiest, Anne Vincent‐Salomon, Hans Kreipe
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 2, Pp 191-205 (2022)
Abstract Invasive lobular breast carcinoma (ILC) is the second most common breast carcinoma (BC) subtype and is mainly driven by loss of E‐cadherin expression. Correct classification of BC as ILC is important for patient treatment. This study asses
Externí odkaz:
https://doaj.org/article/315199064a574f7f8e979a65ce71d4f6
Autor:
Maxsam S. Donta, Yogesh Srivastava, Christina M. Di Mauro, Adriana Paulucci-Holthauzen, M. Neal Waxham, Pierre D. McCrea
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Dendritic arborization is essential for proper neuronal connectivity and function. Conversely, abnormal dendrite morphology is associated with several neurological pathologies like Alzheimer’s disease and schizophrenia. Among major intrinsic mechan
Externí odkaz:
https://doaj.org/article/9fa4f7da1ced4b6c9aa6286282a0504e
Akademický článek
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Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Epithelial ovarian cancer (EOC) remains one of the most lethal gynecologic cancers, and its pathogenetic mechanism remains unclear. Here we show that MUC16 promotes the translocation of p120-catenin (p120ctn) to the cytoplasm and
Externí odkaz:
https://doaj.org/article/8f220d82927d4e7693123d5691d27f9b
Autor:
Josué Curto, Beatriz Del Valle‐Pérez, Aida Villarroel, Guillem Fuertes, Meritxell Vinyoles, Raúl Peña, Antonio García de Herreros, Mireia Duñach
Publikováno v:
Molecular Oncology, Vol 12, Iss 5, Pp 611-629 (2018)
Canonical and noncanonical Wnt pathways share some common elements but differ in the responses they evoke. Similar to Wnt ligands acting through the canonical pathway, Wnts that activate the noncanonical signaling, such as Wnt5a, promote Disheveled (
Externí odkaz:
https://doaj.org/article/db88f0d57d4143b2a6f96e4f526de3c0