Zobrazeno 1 - 10
of 152
pro vyhledávání: '"p-glycoprotein (pgp)"'
Autor:
N. M. Popova, A. V. Shchulkin, I. V. Chernykh, A. S. Esenina, M. M. Gradinar, E. N. Yakusheva
Publikováno v:
Акушерство, гинекология и репродукция, Vol 13, Iss 2, Pp 164-173 (2019)
This review addresses the function of the protein-transporter glycoprotein-P (Pgp, ABCB1 protein) and the expression of its encoding gene MDR1/mdr1 throughout the gestational period in humans and animals. We discuss the relationship between the trans
Externí odkaz:
https://doaj.org/article/02cc39edd35943f8ba648e22c5958e5e
Autor:
Williams, Daniel C., Dantzig, Anne H.
Publikováno v:
In Vitro Cellular & Developmental Biology. Animal, 2002 Jul 01. 38(7), 401-410.
Externí odkaz:
https://www.jstor.org/stable/4295376
Autor:
Nina Hanke, Denise Türk, Dominik Selzer, Sabrina Wiebe, Éric Fernandez, Peter Stopfer, Valerie Nock, Thorsten Lehr
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 556 (2020)
The calcium channel blocker and antiarrhythmic agent verapamil is recommended by the FDA for drug–drug interaction (DDI) studies as a moderate clinical CYP3A4 index inhibitor and as a clinical Pgp inhibitor. The purpose of the presented work was to
Externí odkaz:
https://doaj.org/article/9aa524b20c524240a06f3cd7ae2c54f4
Akademický článek
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Akademický článek
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Publikováno v:
Journal of Computer-Aided Molecular Design. 33:965-971
Development of novel in silico methods for questing novel PgP inhibitors is crucial for the reversal of multi-drug resistance in cancer therapy. Here, we report machine learning based binary classification schemes to identify the PgP inhibitors from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447ebceb9dede4c4757032e871dc2cbb
https://doi.org/10.1007/s10822-019-00253-5
https://doi.org/10.1007/s10822-019-00253-5
Autor:
A. V. Shchulkin, I. V. Chernykh, E. N. Yakusheva, M. M. Gradinar, A. S. Esenina, N. M. Popova
Publikováno v:
Акушерство, гинекология и репродукция, Vol 13, Iss 2, Pp 164-173 (2019)
This review addresses the function of the protein-transporter glycoprotein-P (Pgp, ABCB1 protein) and the expression of its encoding gene MDR1/mdr1 throughout the gestational period in humans and animals. We discuss the relationship between the trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11b2c3ea4d4be75f585bc54be650d50
https://doi.org/10.17749/2313-7347.2019.13.2.164-173
https://doi.org/10.17749/2313-7347.2019.13.2.164-173
Autor:
Di Pietro A., Dayan G., Conseil G., Steinfels E., Krell T., Trompier D., Baubichon-Cortay H., Jault J.-M.
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 32, Iss 8, Pp 925-939 (1999)
Resistance to chemotherapy in cancer cells is mainly mediated by overexpression of P-glycoprotein (Pgp), a plasma membrane ATP-binding cassette (ABC) transporter which extrudes cytotoxic drugs at the expense of ATP hydrolysis. Pgp consists of two hom
Externí odkaz:
https://doaj.org/article/2aa6b1869c854033b0d5c8b6ad7d30a7
Autor:
Hanke, Nina, Türk, Denise, Selzer, Dominik, Wiebe, Sabrina, Fernandez, Éric, Stopfer, Peter, Nock, Valerie, Lehr, Thorsten
Publikováno v:
Pharmaceutics, Vol 12, Iss 556, p 556 (2020)
Pharmaceutics
Volume 12
Issue 6
Pharmaceutics
Volume 12
Issue 6
The calcium channel blocker and antiarrhythmic agent verapamil is recommended by the FDA for drug&ndash
drug interaction (DDI) studies as a moderate clinical CYP3A4 index inhibitor and as a clinical Pgp inhibitor. The purpose of the presented wo
drug interaction (DDI) studies as a moderate clinical CYP3A4 index inhibitor and as a clinical Pgp inhibitor. The purpose of the presented wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e1a769bec43ca74952b222e18ecce0
https://www.mdpi.com/1999-4923/12/6/556
https://www.mdpi.com/1999-4923/12/6/556
Akademický článek
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