Zobrazeno 1 - 10
of 9 029
pro vyhledávání: '"p, phosphorylated"'
Autor:
Branislav Kovacech, Nicholas C. Cullen, Petr Novak, Jozef Hanes, Eva Kontsekova, Stanislav Katina, Vojtech Parrak, Michal Fresser, Jeroen Vanbrabant, Howard H. Feldman, Bengt Winblad, Erik Stoops, Eugeen Vanmechelen, Norbert Zilka
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background The spread of tau pathology closely correlates with the disease course and cognitive decline in Alzheimer’s disease (AD). Tau-targeting immunotherapies are being developed to stop the spread of tau pathology and thus halt diseas
Externí odkaz:
https://doaj.org/article/181a7fda70974743b9f46a457e60777e
Autor:
Yu Katsuyama, Mitsuharu Hattori
Publikováno v:
Neuroscience Research, Vol 208, Iss , Pp 8-14 (2024)
Alzheimer’s disease (AD) is the most prevalent type of dementia; therefore, there is a high demand for therapeutic medication targeting it. In this context, extensive research has been conducted to identify molecular targets for drugs. AD manifests
Externí odkaz:
https://doaj.org/article/dd18c773e547413ba95ec752687c43ac
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract To determine diagnostic value of diffusion tensor imaging (DTI) in amyotrophic lateral sclerosis (ALS) patients and investigate the association between DTI and neurofilaments (NFs), including serum and cerebrospinal fluid (CSF) levels of neu
Externí odkaz:
https://doaj.org/article/fb6df915ccbe42699b9750126b06a9de
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Electrochemical analysis of glucose monitoring without painful blood collection provides a new noninvasive route for monitoring glucose levels. Thus, in this study, biobased cellulosic papers (methylated and phosphorylated one) based glucose
Externí odkaz:
https://doaj.org/article/ef827428de2f43ff8a366ce02163b276
Autor:
Jonna Nilsson, Yiwen Jiang, Malin Johannesson, Marcus Moberg, Rui Wang, Susanne Fabre, Martin Lövdén, Örjan Ekblom, Maria Ekblom
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Blood-based biomarkers of neurodegeneration demonstrate great promise for the diagnosis and prognosis of Alzheimer’s disease. Ultra-sensitive plasma assays now allow for quantification of the lower concentrations in cognitively unimpaired
Externí odkaz:
https://doaj.org/article/bc3631b23d554f7e8305609d52d223f5
Autor:
Xiaqing Ma, Qi Qi, Wenying Wang, Min Huang, Haiyan Wang, Limin Luo, Xiaotao Xu, Tifei Yuan, Haibo Shi, Wei Jiang, Tao Xu
Publikováno v:
Fundamental Research, Vol 4, Iss 4, Pp 820-828 (2024)
The activation of spinal astrocytes accounts for opioid-induced hyperalgesia (OIH), but the underlying mechanisms remain elusive. The presence of astrocyte-neuron lactate shuttle (ANLS) makes astrocytes necessary for some neural function and communic
Externí odkaz:
https://doaj.org/article/130c6dfca20a444f8f04d8c0a7d43659
Autor:
Miriam Rabl, Leonardo Zullo, Piotr Lewczuk, Johannes Kornhuber, Thomas K. Karikari, Kaj Blennow, Henrik Zetterberg, Francesco Bavato, Boris B. Quednow, Erich Seifritz, Armin von Gunten, Christopher Clark, Julius Popp
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Neuropsychiatric symptoms (NPS) are common in older people, may occur early in the development of dementia disorders, and have been associated with faster cognitive decline. Here, our objectives were to investigate whether plasma
Externí odkaz:
https://doaj.org/article/0f38378ecba046c399aaa3cc26c9200c
Autor:
Lufen Huang, Anguo Wu, Jiaxue Chen, Jiamin Zhu, Xulong Qin, Jianing Mi, Bowen Wei, Jianan Wang, Yufeng Liu
Publikováno v:
Food and Agricultural Immunology, Vol 35, Iss 1 (2024)
Acute lung injury (ALI) is a severe form of diffuse lung disease that poses a significant health burden in clinical settings. Numerous natural compounds derived from plants have shown effective anti-inflammatory activities with low toxicity, particul
Externí odkaz:
https://doaj.org/article/51b5d08d54e1473f953a8b742709f88e
Publikováno v:
The Microbe, Vol 5, Iss , Pp 100213- (2024)
Chitosan, a biopolymer made from chitin, has drawn attention from researchers because of its antimicrobial, biocompatible, and biodegradable properties. Sepiella inermis cuttlebone serves as the natural source of chitin, which can undergo phosphoryla
Externí odkaz:
https://doaj.org/article/fc8656a7f801418bbe35a8c0db284699
Autor:
Xifeng Wang, Huayu Yang, Dengcheng Zhan, Haiying Sun, Qiang Huang, Yiping Zhang, Yue Lin, Gen Wei, Fuzhou Hua, Li Liu, Shibiao Chen
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39013- (2024)
Alzheimer's disease (AD) is a gradual neurodegenerative ailment that lacks any disease-modifying intervention. Our objective was to pinpoint pharmacological targets with a focus on amyloid beta (Aβ) and tau to treat and prevent AD in the European po
Externí odkaz:
https://doaj.org/article/9488e6e5b7a341a0aa37c90642243c67