Elevation of serum neurofilament light-chain levels disclose possible occult progressive multifocal leukoencephalopathy and immune reconstitution syndrome in a patient receiving ozanimod: a case report

Autor: Carlos Quintanilla-Bordás, David Gorriz, Laura Cubas-Núñez, Jéssica Castillo-Villalba, Joan Carreres-Polo, Bonaventura Casanova, Francisco Carlos Pérez-Miralles

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

BackgroundWe report the first case of findings suggestive of progressive multifocal leukoencephalopathy and immune restitution syndrome (PML-IRIS) in a patient with multiple sclerosis receiving ozanimod preceded by an unexpected increase in the serum

Externí odkaz: https://doaj.org/article/fde7db9d846049a8b8723f12c0a9862a

Sphingosine-1-phosphate receptor therapies: Advances in clinical trials for CNS-related diseases.

Autor: O'Sullivan S; Drug Development, School of Medicine, Trinity College Dublin, Ireland., Dev KK; Drug Development, School of Medicine, Trinity College Dublin, Ireland. Electronic address: devk@tcd.ie.

Publikováno v: Neuropharmacology [Neuropharmacology] 2017 Feb; Vol. 113 (Pt B), pp. 597-607. Date of Electronic Publication: 2016 Nov 04.