Zobrazeno 1 - 10 of 6 543 pro vyhledávání: '"oxyntomodulin"'
1
Akademický článek
Response to lowering plasma glucose is characterised by decreased oxyntomodulin: Results from a randomised controlled trial.
Autor: Liu Y; School of Medicine, University of Auckland, Auckland, New Zealand., Kimita W; School of Medicine, University of Auckland, Auckland, New Zealand., Bharmal SH; School of Medicine, University of Auckland, Auckland, New Zealand., Petrov MS; School of Medicine, University of Auckland, Auckland, New Zealand. Electronic address: max.petrov@gmail.com.
Publikováno v: Diabetes & metabolic syndrome [Diabetes Metab Syndr] 2024 Jun; Vol. 18 (6), pp. 103052. Date of Electronic Publication: 2024 Jun 10.
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2
Akademický článek
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3
Akademický článek
Emerging roles of oxyntomodulin-based glucagon-like peptide-1/glucagon co-agonist analogs in diabetes and obesity.
Autor: Zhihong Y; Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, College of Medicine, Jiaxing University, Jiaxing 314001, China; College of Pharmacy, Zhejiang University of Technology, Hangzhou 310000, China., Chen W; Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, College of Medicine, Jiaxing University, Jiaxing 314001, China., Qianqian Z; Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, College of Medicine, Jiaxing University, Jiaxing 314001, China., Lidan S; Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, College of Medicine, Jiaxing University, Jiaxing 314001, China. Electronic address: slidan89@zjxu.edu.cn., Qiang Z; The First Hospital of Jiaxing & The Affiliated Hospital of Jiaxing University, Jiaxing 314001, China. Electronic address: zhouqiang8004@163.com., Jing H; School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou 221116, China., Wenxi W; The First Hospital of Jiaxing & The Affiliated Hospital of Jiaxing University, Jiaxing 314001, China; College of Pharmacy, Zhejiang University of Technology, Hangzhou 310000, China., Bhawal R; Proteomics and Metabolomics Facility, Institute of Biotechnology, Cornell University, Ithaca, NY, USA.
Publikováno v: Peptides [Peptides] 2023 Apr; Vol. 162, pp. 170955. Date of Electronic Publication: 2023 Jan 18.
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4
Akademický článek
The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk.
Autor: Valdecantos MP; Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain. pvaldecantos@iib.uam.es.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain. pvaldecantos@iib.uam.es.; Faculty of Experimental Science, Universidad Francisco de Vitoria, Pozuelo de Alarcon, Madrid, Spain. pvaldecantos@iib.uam.es., Ruiz L; Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain., Folgueira C; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Instituto de Salud Carlos III, Madrid, Spain.; Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain., Rada P; Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain., Gomez-Santos B; Department of Physiology, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Leioa, Spain.; BioBizkaia Health Research Institute, Barakaldo, Spain., Solas M; Department of Pharmaceutical Sciences, Division of Pharmacology, University of Navarra, Pamplona, Spain.; IdISNA, Navarra Institute for Health Research, Pamplona, Spain., Hitos AB; Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain., Field J; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Francisco V; Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain., Escalona-Garrido C; Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain., Zagmutt S; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona, Spain., Calderon-Dominguez M; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona, Spain., Mera P; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona, Spain., Garcia-Martinez I; Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain., Maymó-Masip E; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain.; Department of Endocrinology and Nutrition, Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili (IISPV), Tarragona, Spain., Grajales D; Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain., Alen R; Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain., Mora A; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Instituto de Salud Carlos III, Madrid, Spain.; Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain., Sáinz N; University of Navarra, Center for Nutrition Research and Department of Nutrition, Food Science and Physiology, 31008, Pamplona, Spain., Vides-Urrestarazu I; University of Navarra, Center for Nutrition Research and Department of Nutrition, Food Science and Physiology, 31008, Pamplona, Spain., Vilarrasa N; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain.; Obesity Unit and Endocrinology and Nutrition Departments, Hospital Universitari de Bellvitge, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain., Arbones-Mainar JM; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain.; Adipocyte and Fat Biology Laboratory (AdipoFat), Unidad de Investigación Traslacional, Instituto Aragonés de Ciencias de la Salud (IACS), Hospital Universitario Miguel Servet, Zaragoza, Spain., Zaragoza C; Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERcv), Instituto de Salud Carlos III, Madrid, Spain.; Unidad de Investigación Cardiovascular, Universidad Francisco de Vitoria/Servicio de Cardiología, Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Madrid, Spain., Moreno-Aliaga MJ; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain.; IdISNA, Navarra Institute for Health Research, Pamplona, Spain.; University of Navarra, Center for Nutrition Research and Department of Nutrition, Food Science and Physiology, 31008, Pamplona, Spain., Aspichueta P; Department of Physiology, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Leioa, Spain.; BioBizkaia Health Research Institute, Barakaldo, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain., Fernández-Veledo S; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain.; Department of Endocrinology and Nutrition, Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili (IISPV), Tarragona, Spain.; Rovira I Virgili University (URV), Tarragona, Spain., Vendrell J; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain.; Department of Endocrinology and Nutrition, Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili (IISPV), Tarragona, Spain.; Rovira I Virgili University (URV), Tarragona, Spain., Serra D; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain.; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona, Spain., Herrero L; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain.; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona, Spain., Schreiber R; Institute of Molecular Biosciences, University of Graz, 8010, Graz, Austria., Zechner R; Institute of Molecular Biosciences, University of Graz, 8010, Graz, Austria., Sabio G; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Instituto de Salud Carlos III, Madrid, Spain.; Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain., Hornigold D; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Rondinone CM; Research and Early Development, Cardiovascular, Renal and Metabolic Diseases, BioPharmaceuticals R&D, AstraZeneca Ltd, Gaithersburg, MD, USA.; Pep2Tango Therapeutics Inc., Potomac, MD, USA., Jermutus L; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Grimsby J; Research and Early Development, Cardiovascular, Renal and Metabolic Diseases, BioPharmaceuticals R&D, AstraZeneca Ltd, Gaithersburg, MD, USA.; Regeneron Pharmaceuticals, Inc., Internal Medicine, Tarrytown, NY, USA., Valverde ÁM; Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain. avalverde@iib.uam.es.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain. avalverde@iib.uam.es.
Publikováno v: Nature communications [Nat Commun] 2024 Nov 28; Vol. 15 (1), pp. 10342. Date of Electronic Publication: 2024 Nov 28.
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5
Akademický článek
Factors Affecting the Circulating Levels of Oxyntomodulin in Health and After Acute Pancreatitis.
Autor: Bharmal SH; From the School of Medicine, University of Auckland, Auckland, New Zealand., Ko J; From the School of Medicine, University of Auckland, Auckland, New Zealand., Kimita W; From the School of Medicine, University of Auckland, Auckland, New Zealand., Cho J; Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea., Petrov MS; From the School of Medicine, University of Auckland, Auckland, New Zealand.
Publikováno v: Pancreas [Pancreas] 2022 Aug 01; Vol. 51 (7), pp. 774-783.
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6
Akademický článek
Development of a selective, sensitive and robust oxyntomodulin dual monoclonal antibody immunoassay.
Autor: Umberger TS; Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA., Ming W; Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA., Cox JM; Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA., Konrad RJ; Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA., Siegel RW; Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN 46285, USA.
Publikováno v: Bioanalysis [Bioanalysis] 2022 Sep; Vol. 14 (18), pp. 1229-1239. Date of Electronic Publication: 2022 Nov 15.
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7
Akademický článek
Oxyntomodulin attenuates TNF-α induced neuropathic pain by inhibiting the activation of the NF-κB pathway.
Autor: Zhang, Yu1 (AUTHOR), Yuan, Liyong1 (AUTHOR) yuanliyong1973@163.com, Chen, Yuebo1 (AUTHOR), Lin, Chunyan1 (AUTHOR), Ye, Guangyao1 (AUTHOR)
Publikováno v: Molecular Medicine Reports. Dec2019, Vol. 20 Issue 6, p5223-5228. 6p.
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8
Akademický článek
(D-Ser2) oxyntomodulin recovers hippocampal synaptic structure and theta rhythm in Alzheimer’s disease transgenic mice
Autor: Guang-Zhao Yang, Qi-Chao Gao, Wei-Ran Li, Hong-Yan Cai, Hui-Min Zhao, Jian-Ji Wang, Xin-Rui Zhao, Jia-Xin Wang, Mei-Na Wu, Jun Zhang, Christian Hölscher, Jin-Shun Qi, Zhao-Jun Wang
Publikováno v: Neural Regeneration Research, Vol 17, Iss 9, Pp 2072-2078 (2022)
In our previous studies, we have shown that (D-Ser2) oxyntomodulin (Oxm), a glucagon-like peptide 1 (GLP-1) receptor (GLP1R)/glucagon receptor (GCGR) dual agonist peptide, protects hippocampal neurons against Aβ1–42-induced cytotoxicity, and stabi
Externí odkaz: https://doaj.org/article/40580751a2404346bfa59e6c57a5ba66
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9
Akademický článek
Fasting oxyntomodulin, glicentin, and gastric inhibitory polypeptide levels are associated with activation of reward- and attention-related brain centres in response to visual food cues in adults with obesity: A cross-sectional functional MRI study.
Autor: Perakakis N; Division of Endocrinology, Beth Israel Deaconess Medical Centre/Harvard Medical School, Boston, Massachusetts.; Section of Endocrinology, VA Boston Healthcare System, Jamaica Plain, Massachusetts., Farr OM; Division of Endocrinology, Beth Israel Deaconess Medical Centre/Harvard Medical School, Boston, Massachusetts.; Section of Endocrinology, VA Boston Healthcare System, Jamaica Plain, Massachusetts., Mantzoros CS; Division of Endocrinology, Beth Israel Deaconess Medical Centre/Harvard Medical School, Boston, Massachusetts.; Section of Endocrinology, VA Boston Healthcare System, Jamaica Plain, Massachusetts.
Publikováno v: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2021 May; Vol. 23 (5), pp. 1202-1207. Date of Electronic Publication: 2021 Jan 22.
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10
Akademický článek
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