Zobrazeno 1 - 10
of 871
pro vyhledávání: '"oxidized nucleotide"'
Autor:
Zhang, Hui-Xia, Yu, Dian, Sun, Jian-Feng, Zeng, Ling, Wang, Cai-Yun, Bai, Li-Ping, Zhu, Guo-Yuan, Jiang, Zhi-Hong, Zhang, Wei
Publikováno v:
In Environment International August 2023 178
Autor:
Hui-Xia Zhang, Dian Yu, Jian-Feng Sun, Ling Zeng, Cai-Yun Wang, Li-Ping Bai, Guo-Yuan Zhu, Zhi-Hong Jiang, Wei Zhang
Publikováno v:
Environment International, Vol 178, Iss , Pp 108038- (2023)
Acetamiprid is poisonous to mammals due to severe acetamiprid-induced oxidative stress that could cause mitochondrial dysfunctions, lipid and protein oxidation, inflammation, apoptosis, and DNA damage. Evidence has accumulated for the role of oxidati
Externí odkaz:
https://doaj.org/article/11a6d01ad60940d1bb197ad5615c046b
Akademický článek
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Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
How DNA polymerases discriminate against oxidized and undamaged nucleotides during DNA repair is not fully understood. Here, the authors reveal high-resolution timelapse X-ray crystallography snapshots of DSB repair polymerase μ undergoing DNA synth
Externí odkaz:
https://doaj.org/article/64968d1c0b29445aac6abe67bd0ccdd1
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Kim Theilgaard-Mönch, Thomas Helleday, Ulrika Warpman Berglund, Sophia Engelhard, Camilla Vittori, Kumar Sanjiv, Kristian Reckzeh, Montserrat Estruch, Anders Centio
Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d2b851cc283c27330d8dc9028e56f9
https://doi.org/10.1158/1535-7163.22522218.v1
https://doi.org/10.1158/1535-7163.22522218.v1
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Oxidative stress in cells leads to the oxidations of DNA precursors. Here the authors show that these oxidized precursors can be incorporatedin vivoduring base excision repair, leading to DNA breaks and cytotoxicity.
Externí odkaz:
https://doaj.org/article/d2a81dca650b43be9b6e7c1748afddde
Autor:
Kim Theilgaard-Mönch, Thomas Helleday, Ulrika Warpman Berglund, Sophia Engelhard, Camilla Vittori, Kumar Sanjiv, Kristian Reckzeh, Montserrat Estruch, Anders Centio
Currently, the majority of patients with acute myeloid leukemia (AML) still die of their disease due to primary resistance or relapse toward conventional reactive oxygen species (ROS)- and DNA damage–inducing chemotherapy regimens. Herein, we explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d214d6aedb84973092fd78ecb7c18fe
https://doi.org/10.1158/1535-7163.c.6543309
https://doi.org/10.1158/1535-7163.c.6543309
Autor:
Freudenthal, Bret D.1, Beard, William A.1, Perera, Lalith1, Shock, David D.1, Kim, Taejin2, Schlick, Tamar2, Wilson, Samuel H.1
Publikováno v:
Nature. 1/29/2015, Vol. 517 Issue 7536, p635-639. 5p.