Zobrazeno 1 - 10
of 1 887
pro vyhledávání: '"oxLDL"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
IntroductionRecent findings demonstrate that high density lipoprotein (HDL) function rather than HDL-cholesterol levels themselves may be a better indicator of cardiovascular disease risk. One mechanism by which HDL can become dysfunctional is throug
Externí odkaz:
https://doaj.org/article/86d4abbdc710463d95dbf6f70b7655b1
Autor:
Wataru Nihei, Ayako Kato, Tatsuhito Himeno, Masaki Kondo, Jiro Nakamura, Hideki Kamiya, Kazunori Sango, Koichi Kato
Publikováno v:
Neurology International, Vol 16, Iss 2, Pp 370-379 (2024)
Increased low-density lipoprotein levels are risk factors for diabetic neuropathy. Diabetes mellitus is associated with elevated metabolic stress, leading to oxidised low-density lipoprotein formation. Therefore, it is important to investigate the me
Externí odkaz:
https://doaj.org/article/4549612edccd42fab54f765a405dc851
Autor:
Harri Juhani Saarinen, Jorma Lahtela, Päivi Mähönen, Ari Palomäki, for the Hämeenlinna Metabolic Syndrome Research Program Study Group
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background All-cause mortality and cardiovascular disease are increased in subjects with metabolic syndrome (MetS). Risk scores are used to predict individual risk of heart disease. We performed a long-term follow-up study to investigate whe
Externí odkaz:
https://doaj.org/article/8fbbe2edf5e443c4b3c84565bc19a39e
Autor:
Alessandro Scalia, Maxime Coquay, Nadège Kindt, Pierre Duez, Rania Aro, Fabrice Journé, Mathilde Fabjanczyk, Anne Trelcat, Stéphane Carlier
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9487 (2024)
Recent findings from the World Heart Federation (WHF) reported a significant increase in cardiovascular disease (CVD)-related deaths, highlighting the urgent need for effective prevention strategies. Atherosclerosis, a key precursor to CVD, involves
Externí odkaz:
https://doaj.org/article/201925eb219340d7875ca4a260cf1e4b
Autor:
Thangarajeswari Mohan, Abinayaa Rajkumar, Gokulprasanth Panchalingam, Debadatta Nayak, Malathi Raghunathan, Kalaiselvi Periandavan
Publikováno v:
Journal of Ayurveda and Integrative Medicine, Vol 15, Iss 1, Pp 100850- (2024)
Background: Oxidized LDL (OxLDL), the key player in atherogenesis modulates endothelial dysfunction, initiates monocyte recruitment, accentuates foam cell formation, and flares up inflammatory and apoptotic events. Even though homeopathic preparation
Externí odkaz:
https://doaj.org/article/c8e529246de8473d9701c1ca6eb9484b
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-22 (2023)
Abstract Background and aims The accumulation of misfolded proteins, encoded by genetic variants of functional genes leads to Endoplasmic Reticulum (ER) stress, which is a critical consequence in human disorders such as familial hypercholesterolemia,
Externí odkaz:
https://doaj.org/article/d9a5bfeb8a49475483a01fe270e1b6a0
Autor:
Rouhollah Mousavizadeh, Charlie M. Waugh, Erin DeBruin, Robert G. McCormack, Vincent Duronio, Alex Scott
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background Previous studies have shown that patients with hypercholesterolemia experience elevated levels of oxidized LDL (oxLDL), a molecule which triggers inflammation and collagenase activity. In this study we discovered novel mechanistic
Externí odkaz:
https://doaj.org/article/7d04b547449b4ff5a3946e90b5bb3e09
Publikováno v:
Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)
Abstract The anti‐tumor immune response relies on interactions among tumor cells and immune cells. However, the molecular mechanisms by which tumor cells regulate DCs as well as DCs regulate T cells remain enigmatic. Here, the authors identify a su
Externí odkaz:
https://doaj.org/article/c953d2d18844485a9aa4a7eef0902b49
Autor:
Roman Witzel, Annika Block, Solvey Pollmann, Leandra Oetzel, Fenja Fleck, Gabriel A. Bonaterra, Ralf Kinscherf, Anja Schwarz
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundPituitary adenylate cyclase-activating polypeptide (PACAP) acts as an anti-atherogenic neuropeptide and plays an important role in cytoprotective, as well as inflammatory processes, and cardiovascular regulation. Therefore, the aim of this
Externí odkaz:
https://doaj.org/article/aaae726afec74cf2a9c001acd1b4dcb5
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-13 (2022)
Abstract Background Endometriosis (EMS) is a “tumour-like” gynaecological disease with distant metastasis, and studies have shown that EMS can induce distant metastasis through vascular vessels, but the driving factors and their mechanism are not
Externí odkaz:
https://doaj.org/article/df115232f6da4a84856b162032c04d7e