Zobrazeno 1 - 10
of 10 245
pro vyhledávání: '"osteoblast differentiation"'
Publikováno v:
Shipin Kexue, Vol 45, Iss 17, Pp 35-41 (2024)
Catfish bone collagen peptide-calcium (F3-Ca) chelatate, which had been prepared in our laboratory, was evaluated for its effect on calcium transport and absorption using a Caco-2 cell model. Its effect on the alkaline phosphatase (ALP) activity of o
Externí odkaz:
https://doaj.org/article/f1245b1d4b8b46e9ba3940887ddf4e1a
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-11 (2024)
Abstract Erythropoietin (EPO), expressed in red blood progenitor cells, primarily regulates erythropoiesis by binding to its receptor. Besides anemia, recent studies have identified new therapeutic indications for EPO that are not connected to red bl
Externí odkaz:
https://doaj.org/article/7e307861720d4d6a89f8784bf52c8539
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 9, Pp 9624-9638 (2024)
Recent studies have confirmed that melatonin and N6-methyladenosine (m6A) modification can influence bone cell differentiation and bone formation. Melatonin can also regulate a variety of biological processes through m6A modification. Heterogeneous n
Externí odkaz:
https://doaj.org/article/c91d7c3783fe41669d94ea27e0a44b66
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Glucocorticoid-induced osteoporosis (GIOP) is the most common type of secondary osteoporosis. Recently, autophagy has been found to be related with the development of various diseases, including osteoporosis and osteoblast differe
Externí odkaz:
https://doaj.org/article/7c56e3cc155a48a5be3133559f6bca48
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 144855-8 (2024)
Recent scientific investigations have revealed the intricate mechanisms underlying bone formation, emphasizing the essential role of long non-coding RNAs (lncRNAs) as critical regulators. This process, essential for skeletal strength and functionalit
Externí odkaz:
https://doaj.org/article/0aa97375c6904d5a81b3aa99d8b0d37b
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Effective bone formation relies on osteoblast differentiation, a process subject to intricate post-translational regulation. Ubiquitin-specific proteases (USPs) repress protein degradation mediated by the ubiquitin-proteasome path
Externí odkaz:
https://doaj.org/article/0ec006699eb54fb498715352cdda22d9
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Increasing evidence shows the pivotal significance of miRNAs in the pathogenesis of osteoporosis. miR-381-3p has been identified as an inhibitor of osteogenesis. This study explored the role and mechanism of miR-381-3p in postmeno
Externí odkaz:
https://doaj.org/article/29cf8943bae94ec6935d2c8b502e35a2
Autor:
Qing Jiang, Kenichi Nagano, Takeshi Moriishi, Hisato Komori, Chiharu Sakane, Yuki Matsuo, Zhiguo Zhang, Riko Nishimura, Kosei Ito, Xin Qin, Toshihisa Komori
Publikováno v:
Journal of Orthopaedic Translation, Vol 47, Iss , Pp 161-175 (2024)
Background: Zinc finger-containing transcription factor Osterix/Specificity protein-7 (Sp7) is an essential transcription factor for osteoblast differentiation. However, its functions in differentiated osteoblasts remain unclear and the effects of os
Externí odkaz:
https://doaj.org/article/05baa11ff1b9462c84e68d628c3026ff
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-14 (2024)
Abstract Background Circular RNAs (circRNAs) are involved in the progression of osteoporosis; however, their impact on osteogenic differentiation has yet to be fully elucidated. In this study, we identified a novel circRNA known as circZfp644-205 and
Externí odkaz:
https://doaj.org/article/a4067c0dadcc48de92ca35eea5919f43
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117490- (2024)
In the process of bone metabolism and bone remodeling, bone marrow mesenchymal stem cells (BM-MSCs) differentiate into osteoblasts (OBs) under certain conditions to enable the formation of new bone, and normal bone reconstruction and pathological bon
Externí odkaz:
https://doaj.org/article/7ea2bb5fb43a4bc4b9ffee87d4635e2b