Zobrazeno 1 - 10
of 10
pro vyhledávání: '"orthotopic TCR replacement"'
Autor:
Reimann, Hannah a, b, ⁎, Moosmann, Carolin c, Schober, Kilian c, d, Lang, Vanessa a, b, Verhagen, Johan a, e, f, Zeun, Julia a, b, Mackensen, Andreas a, b, Kremer, Anita N. a, b, Völkl, Simon a, b, Aigner, Michael a, b
Publikováno v:
In Immunobiology September 2023 228(5)
Autor:
Stief, Tanja A. 1, 5, 8, Kaeuferle, Theresa 1, 5, 8, Müller, Thomas R. 2, 5, 8, Döring, Michaela 3, Jablonowski, Lena M. 1, Schober, Kilian 2, 5, Feucht, Judith 3, 4, Dennehy, Kevin M. 6, 7, Willier, Semjon 1, Blaeschke, Franziska 1, 3, Handgretinger, Rupert 3, Lang, Peter 3, Busch, Dirk H. 2, 5, Feuchtinger, Tobias 1, 3, 5, ∗
Publikováno v:
In Molecular Therapy 5 January 2022 30(1):198-208
Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy
Autor:
Müller, Thomas R. 1, 2, Jarosch, Sebastian 1, Hammel, Monika 1, Leube, Justin 1, Grassmann, Simon 1, 3, Bernard, Bettina 1, Effenberger, Manuel 1, Andrä, Immanuel 1, Chaudhry, M. Zeeshan 4, 5, Käuferle, Theresa 2, 6, Malo, Antje 7, Cicin-Sain, Luka 4, 5, Steinberger, Peter 8, Feuchtinger, Tobias 2, 6, Protzer, Ulrike 2, 7, Schumann, Kathrin 1, 9, Neuenhahn, Michael 1, 2, Schober, Kilian 1, 10, ∗, Busch, Dirk H. 1, 2, 9, 10, 11, ∗∗
Publikováno v:
In Cell Reports Medicine 17 August 2021 2(8)
Publikováno v:
Cells, Vol 9, Iss 6, p 1367 (2020)
Natural adaptive immunity co-evolved with pathogens over millions of years, and adoptive transfer of non-engineered T cells to fight infections or cancer so far exhibits an exceptionally safe and functional therapeutic profile in clinical trials. How
Externí odkaz:
https://doaj.org/article/fc1505a8836d4a05a25c00bf46f19c32
Autor:
Busheng Xue, Kristina von Heyking, Hendrik Gassmann, Mansour Poorebrahim, Melanie Thiede, Kilian Schober, Josef Mautner, Julia Hauer, Jürgen Ruland, Dirk H. Busch, Uwe Thiel, Stefan E. G. Burdach
Publikováno v:
Cancers 14:5485 (2022)
Cancers; Volume 14; Issue 22; Pages: 5485
Cancers (Basel)
Cancers; Volume 14; Issue 22; Pages: 5485
Cancers (Basel)
Ewing sarcoma (EwS) is a highly malignant sarcoma of bone and soft tissue with early metastatic spread and an age peak in early puberty. The prognosis in advanced stages is still dismal, and the long-term effects of established therapies are severe.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49799ae1fe7cc63650a8f1d08b199d16
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66832
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66832
Akademický článek
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Autor:
Müller, Thomas Raffael
Reprogramming a T cell’s antigen-HLA specificity through T cell receptor (TCR) gene-editing provides exciting new options for adoptive T cell therapy. In this thesis, we investigated two main aspects of TCR editing: TCR-intrinsic functionality and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______518::679b99316bef5f36ec33e1e8ed6c254c
https://mediatum.ub.tum.de/doc/1579736/document.pdf
https://mediatum.ub.tum.de/doc/1579736/document.pdf
Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy
Autor:
Antje Malo, Luka Cicin-Sain, Michael Neuenhahn, Sebastian Jarosch, Dirk H. Busch, Ulrike Protzer, Kilian Schober, Justin Leube, Simon Grassmann, Kathrin Schumann, Manuel Effenberger, T. Müller, Monika Hammel, M. Zeeshan Chaudhry, Bettina Bernard, Immanuel Andrä, Peter Steinberger, Tobias Feuchtinger, Theresa Käuferle
Publikováno v:
Cell Reports Medicine
Cell reports. Medicine
United States
Cell reports. Medicine
United States
Summary Adoptive transfer of T cells expressing a transgenic T cell receptor (TCR) has the potential to revolutionize immunotherapy of infectious diseases and cancer. However, the generation of defined TCR-transgenic T cell medicinal products with pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d483a4b09c3cdd810481c55bb68b7940
http://europepmc.org/articles/PMC8385324
http://europepmc.org/articles/PMC8385324
Publikováno v:
Cells, Vol 9, Iss 1367, p 1367 (2020)
Cells
Cells
Natural adaptive immunity co-evolved with pathogens over millions of years, and adoptive transfer of non-engineered T cells to fight infections or cancer so far exhibits an exceptionally safe and functional therapeutic profile in clinical trials. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebf94ea71f25014cfc249cfcd896cae
https://www.mdpi.com/2073-4409/9/6/1367
https://www.mdpi.com/2073-4409/9/6/1367
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.