Zobrazeno 1 - 10
of 1 719
pro vyhledávání: '"oridonin"'
Autor:
Mengru Cai, Tingting Fu, Rongyue Zhu, Panxiang Hu, Jiahui Kong, Shilang Liao, Yuji Du, Yongqiang Zhang, Changhai Qu, Xiaoxv Dong, Xingbin Yin, Jian Ni
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4073-4086 (2024)
Ferroptosis is a recently discovered pathway for regulated cell death pathway. However, its efficacy is affected by limited iron content and intracellular ion homeostasis. Here, we designed a metal-organic framework (MOF)-based nanoplatform that inco
Externí odkaz:
https://doaj.org/article/a35ef405f47f4c92a9c4a9f6bdad4463
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-6 (2024)
Abstract To study the source and content change of oridonin in the ice ribbons, the contents of oridonin in the ice ribbons and bleeding sap of Isodon rubescens at different times were determined with RP-HPLC. The paraffin sectioning and electron mic
Externí odkaz:
https://doaj.org/article/7e34a081252a4952bba651187f6b2990
Autor:
Yang Gao, Zhuang Peng, Huiyu Yang, Xinrui Zhang, Yuhan Zhao, Zeyu Hou, Bo Su, Kai Li, Cunlin Zhang
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Rabdosia rubescens, a Chinese herbal medicine with anticancer properties, contains two active ingredients: oridonin and ponicidin. Both compounds exhibit antitumor effects by inducing tumor cell apoptosis and autophagy and inhibiting tumor cell proli
Externí odkaz:
https://doaj.org/article/0ad8aab5b3e44b75b8a8134f4ea98435
Autor:
Yi Liu, Xiaoning Wang, Hui Feng, Xinyan Li, Runyu Yang, Mengyao Zhang, Yue Du, Ruimin Liu, Minna Luo, Zhiyi Li, Bo Liu, Jincheng Wang, Wenjuan Wang, Feifei An, Fan Niu, Pengcheng He
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Discrepancies in the utilization of reactive oxygen species (ROS) between cancer cells and their normal counterparts constitute a pivotal juncture for the precise treatment of cancer, delineating a noteworthy trajectory in the fie
Externí odkaz:
https://doaj.org/article/cfc35d9c75084dc9b9062c5b789e9449
Autor:
Jushuang Li, Lan Shu, Qianqian Jiang, Baohong Feng, Zhimin Bi, Geli Zhu, Yanxia Zhang, Xiangyou Li, Jun Wu
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
Diabetic nephropathy (DN) is one of the most serious and frequent complications among diabetes patients and presently constitutes vast the cases of end-stage renal disease worldwide. Tubulointerstitial fibrosis is a crucial factor related to the occu
Externí odkaz:
https://doaj.org/article/d14fbeec293a4c90b58919b2a6e6734a
Autor:
Feifan Zhang, Yang Hao, Ning Yang, Man Liu, Yage Luo, Ying Zhang, Jian Zhou, Hongjian Liu, Jitian Li
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Osteosarcoma (OS) is one of the most common aggressive bone malignancy tumors in adolescents. With the application of new chemotherapy regimens, finding new and effective anti-OS drugs to coordinate program implementation is urgen
Externí odkaz:
https://doaj.org/article/4aee132f739740d0a631cf2bd9b11a90
Autor:
Yulian Chen, Huanguo Jiang, Zhikun Zhan, Jindi Lu, Tanwei Gu, Ping Yu, Weimin Liang, Xi Zhang, Shilong Zhong, Lan Tang
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 11, Pp 1281-1295 (2023)
Hepatosteatosis is characterized by abnormal accumulation of triglycerides (TG), leading to prolonged and chronic inflammatory infiltration. To date, there is still a lack of effective and economical therapies for hepatosteatosis. Oridonin (ORI) is a
Externí odkaz:
https://doaj.org/article/cecf1a9f2ae846f588426727d4779d51
Publikováno v:
Molecules, Vol 29, Iss 11, p 2643 (2024)
Oridonin (Ori) is a naturally existing diterpenoid substance that mainly exists in the Chinese medicinal plant Rabdosia rubescens. It was previously found to possess intriguing biological properties; however, the quick clearance from plasma and limit
Externí odkaz:
https://doaj.org/article/2bf1e5cf05764d20a1c47fa5b2ec95f3
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Autor:
Fangyuan Zhou, Haiyang Gao, Luorui Shang, Jinxiao Li, Mengqi Zhang, Shuhan Wang, Runze Li, Lin Ye, Shenglan Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background The incidence of colorectal cancer and cancer death rate are increasing every year, and the affected population is becoming younger. Traditional Chinese medicine therapy has a unique effect in prolonging survival time and improvin
Externí odkaz:
https://doaj.org/article/546e26ce56f6486d8b5c213dad15e40a