Zobrazeno 1 - 10
of 127
pro vyhledávání: '"organ‐on‐chips"'
Autor:
Danielle S.K. Brasino, Sean D. Speese, Kevin Schilling, Carolyn E. Schutt, Michelle C. Barton
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract Gut microbiome composition is tied to diseases ranging from arthritis to cancer to depression. However, mechanisms of action are poorly understood, limiting development of relevant therapeutics. Organ‐on‐chip platforms, which model minim
Externí odkaz:
https://doaj.org/article/aa8ea7bcb771466fa068ae65ec76cfa8
Autor:
Alonso Ingar Romero, Qianru Jin, Kevin Kit Parker, Joe Alexander, Bernhard Wolfrum, Tetsuhiko F. Teshima
Publikováno v:
Advanced Intelligent Systems, Vol 6, Iss 9, Pp n/a-n/a (2024)
Studying the behavior of electroactive cells, such as firing dynamics and chemical secretion, is crucial for developing human disease models and therapeutics. Following the recent advances in cell culture technology, traditional monolayers are optimi
Externí odkaz:
https://doaj.org/article/058010a5eaae46d989eced01c6d3409b
Autor:
Xuerui Wang, Jinnuo Lu, Yixiao Huang, Xinhao Liu, Guocheng Fang, Chih-Tsung Yang, Zhaobin Guo
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/e49811bdf4c44c38a8f58fae6fa35e2c
Akademický článek
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Publikováno v:
Interdisciplinary Medicine, Vol 1, Iss 1, Pp n/a-n/a (2023)
Abstract The nervous system plays an irreplaceable role in maintaining homeostasis and coordinating with the external environment. However, the incidence of neurological diseases is high and increasing year by year. Long drug development cycles, low
Externí odkaz:
https://doaj.org/article/67ab6c20b1c24bf69e5fec23f12edce7
Organoids and microphysiological systems: Promising models for accelerating AAV gene therapy studies
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The FDA has predicted that at least 10-20 gene therapy products will be approved by 2025. The surge in the development of such therapies can be attributed to the advent of safe and effective gene delivery vectors such as adeno-associated virus (AAV).
Externí odkaz:
https://doaj.org/article/f5d2079b59f24b40aa1b2d720e58f502
Akademický článek
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Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 54 (2022)
The liver produces and stores various nutrients that are necessary for the body and serves as a chemical plant, metabolizing carbohydrates, fats, hormones, vitamins, and minerals. It is also a vital organ for detoxifying drugs and exogenous harmful s
Externí odkaz:
https://doaj.org/article/5b67b744f2f64fb19cc5eca9f19e43da
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/94bd7da4956d46af92c7240541fa9d2f
Autor:
Zhang, Feng
The vascular system, responsible for the transport of nutrients, oxygen, and waste removal, overcomes the limitations of oxygen diffusion in solid tissues through blood perfusion, thereby preventing necrosis. The mechanical stimuli from blood flow ar
Externí odkaz:
http://hdl.handle.net/11375/29647