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pro vyhledávání: '"ordinal toxicity grade"'
Autor:
Mourad Tighiouart, André Rogatko
Publikováno v:
Entropy, Vol 26, Iss 8, p 687 (2024)
We present a Bayesian adaptive design for dose finding in oncology trials with application to a first-in-human trial. The design is based on the escalation with overdose control principle and uses an intermediate grade 2 toxicity in addition to the t
Externí odkaz:
https://doaj.org/article/e9b89069d5164b8f82814dd20880ea88
Akademický článek
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Publikováno v:
PLoS ONE. Mar2014, Vol. 9 Issue 3, p1-13. 13p.
Autor:
Qayed, Muna, Cash, Thomas, Tighiouart, Mourad, MacDonald, Tobey J., Goldsmith, Kelly C., Tanos, Rachel, Kean, Leslie, Watkins, Benjamin, Suessmuth, Yvonne, Wetmore, Cynthia, Katzenstein, Howard M.
Publikováno v:
Pediatric Blood & Cancer; Apr2020, Vol. 67 Issue 4, p1-9, 9p
Autor:
Peter F. Thall
Bayesian Precision Medicine presents modern Bayesian statistical models and methods for identifying treatments tailored to individual patients using their prognostic variables and predictive biomarkers. The process of evaluating and comparing treatme
Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years