Zobrazeno 1 - 10
of 645
pro vyhledávání: '"opscc"'
Autor:
Qizhang Yan, Pengning Chen, Xinyu Chen, Guanxi Chen, Lin Luo, Ping Ruan, Dahai Yu, Xiaojuan Zeng, Mengyu Zhou
Publikováno v:
PeerJ, Vol 12, p e18286 (2024)
Background The incidence of oropharyngeal squamous cell carcinoma (OPSCC) mediated by human papilloma virus (HPV) has been steadily increasing worldwide. The specific pathogenesis of HPV-mediated head and neck squamous cell carcinoma (HNSCC) usually
Externí odkaz:
https://doaj.org/article/fe23871df962425fb12a130cb21712ab
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background Despite the better prognosis associated with human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC), some patients experience relapse and succumb to the disease; thus, there is a need for biomarkers iden
Externí odkaz:
https://doaj.org/article/8ff0e5758edc4d9687743882dde783ba
Autor:
Adrian Fehn, Adrian von Witzleben, Ayla Grages, Tsima Abou Kors, Jasmin Ezić, Annika C. Betzler, Cornelia Brunner, Patrick J. Schuler, Marie-Nicole Theodoraki, Thomas K. Hoffmann, Simon Laban
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 59, Iss , Pp 101086- (2025)
Failure of immunotherapy in head and neck squamous cell carcinoma (HNSCC) patients represents an unmet need to augment leverage of adaptive immunity. Immunogenic cancer-testis antigen (CTA) expression as well as lymphocyte differentiation and functio
Externí odkaz:
https://doaj.org/article/f1c3848449674bbf8820fe8021af9d84
Publikováno v:
Oral Oncology Reports, Vol 11, Iss , Pp 100564- (2024)
Advancements in Immune checkpoint inhibitor (ICI) treatment have greatly changed the way oropharyngeal squamous cell carcinoma (OPSCC) is treated. This paper examines the crucial advancements and their consequences for clinical practice. Initially, t
Externí odkaz:
https://doaj.org/article/8afde2a006654346a07c6554672ef9fb
Autor:
Tsima Abou Kors, Matthias Meier, Lena Mühlenbruch, Annika C. Betzler, Franziska Oliveri, Martin Bens, Jaya Thomas, Johann M. Kraus, Johannes Doescher, Adrian von Witzleben, Linda Hofmann, Jasmin Ezic, Diana Huber, Julian Benckendorff, Thomas F. E. Barth, Jens Greve, Patrick J. Schuler, Cornelia Brunner, Jonathan M. Blackburn, Thomas K. Hoffmann, Christian Ottensmeier, Hans A. Kestler, Hans-Georg Rammensee, Juliane S. Walz, Simon Laban
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe human leukocyte antigen complex (HLA) is essential for inducing specific immune responses to cancer by presenting tumor-associated peptides (TAP) to T cells. Overexpressed tumor associated antigens, mainly cancer-testis antigens (CTA)
Externí odkaz:
https://doaj.org/article/395296b0c62b42a7af04bb14da175331
Autor:
Nienke D. Sijtsema, Iris Lauwers, Gerda M. Verduijn, Mischa S. Hoogeman, Dirk H.J. Poot, Juan A. Hernandez-Tamames, Aad van der Lugt, Marta E. Capala, Steven F. Petit
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 30, Iss , Pp 100574- (2024)
Background and purpose: Diffusion-weighted imaging (DWI) is a promising technique for response assessment in head-and-neck cancer. Recently, we optimized Non-Gaussian Intravoxel Incoherent Motion Imaging (NG-IVIM), an extension of the conventional ap
Externí odkaz:
https://doaj.org/article/430d9008a2cd4c1d872e871af7dea3b2
Autor:
Charlotte Klasen, Nora Wuerdemann, Pauline Rothbart, Johanna Prinz, Hans Nicholaus Casper Eckel, Malte Suchan, Christopher Kopp, Jannik Johannsen, Maria Ziogas, Arthur Charpentier, Christian Ulrich Huebbers, Shachi Jenny Sharma, Christine Langer, Christoph Arens, Steffen Wagner, Alexander Quaas, Jens Peter Klußmann
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Background Oropharyngeal squamous cell carcinoma (OPSCC) is the only subgroup of head neck cancer that presents with an increased incidence. Gender-specific studies in other cancer entities have revealed differences in treatment response and prognosi
Externí odkaz:
https://doaj.org/article/9d687055e9734774a545a1ea8d08fe85
Autor:
Jadwiga Gaździcka, Krzysztof Biernacki, Silvia Salatino, Karolina Gołąbek, Dorota Hudy, Agata Świętek, Katarzyna Miśkiewicz-Orczyk, Anna Koniewska, Maciej Misiołek, Joanna Katarzyna Strzelczyk
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 7, Pp 5645-5661 (2023)
The growing incidence of oropharyngeal squamous cell carcinoma (OPSCC) calls for better understanding of the mutational landscape of such cases. Mucins (MUCs) are multifunctional glycoproteins expressed by the epithelial cells and may be associated w
Externí odkaz:
https://doaj.org/article/4072773d8ff846e797749b4ef0b32548
Autor:
Jadwiga Gaździcka, Krzysztof Biernacki, Karolina Gołąbek, Katarzyna Miśkiewicz-Orczyk, Natalia Zięba, Maciej Misiołek, Joanna Katarzyna Strzelczyk
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 914 (2024)
Background: Aberrant DNA methylation is a common epigenetic modification in cancers, including oropharyngeal squamous cell carcinoma (OPSCC) and oral squamous cell carcinoma (OSCC). Therefore, the analysis of methylation levels appears necessary to i
Externí odkaz:
https://doaj.org/article/c89d1512d88146aa96cf38d4f95a30b9
Autor:
Gunnar Wichmann, Nathalie Vetter, Claudia Lehmann, Ramona Landgraf, Ilias Doxiadis, Rebecca Großmann, Ekaterina Vorobeva, Andreas Dietz, Veit Zebralla, Susanne Wiegand, Theresa Wald
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundEffective immune surveillance requires a functioning immune system and natural killer (NK) and T cells for adequate innate and antigen-specific immune responses critically depending on human leukocyte antigens (HLAs) and haplotypes represen
Externí odkaz:
https://doaj.org/article/ea812ba7f3f84ff885cec369b7a57e3c