Zobrazeno 1 - 10
of 198
pro vyhledávání: '"opioid-induced respiratory depression"'
Autor:
Albert Dahan, Thomas S. Franko, James W. Carroll, David S. Craig, Callie Crow, Jeffrey L. Galinkin, Justin C. Garrity, Joanne Peterson, David B. Rausch
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
Opioid-induced respiratory depression (OIRD) deaths are ~80,000 a year in the US and are a major public health issue. Approximately 90% of fatal opioid-related deaths are due to synthetic opioids such as fentanyl, most of which is illicitly manufactu
Externí odkaz:
https://doaj.org/article/d4ede227944f44e18d4528fedab8af85
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/5e935cd9e657403393fc1f6455d7ddbf
Autor:
Barbara Palkovic, Sanda Mustapic, Ivana Saric, Eckehard A. E. Stuth, Astrid G. Stucke, Edward J. Zuperku
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction:In vivo studies using selective, localized opioid antagonist injections or localized opioid receptor deletion have identified that systemic opioids dose-dependently depress respiratory output through effects in multiple respiratory-relat
Externí odkaz:
https://doaj.org/article/1903465c30534bc9ade77857ab3602fa
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Opioids provide analgesia, as well as modulate sleep and respiration, all by possibly acting on the μ-opioid receptors (MOR). MOR’s are ubiquitously present throughout the brain, posing a challenge for understanding the precise anatomical substrat
Externí odkaz:
https://doaj.org/article/c0d20f10c2b140f08c0355f2dd983836
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Opioid medications are the mainstay of pain management but present substantial side-effects such as respiratory depression which can be lethal with overdose. Most opioid drugs, such as fentanyl, act on opioid receptors such as the G-protein-coupled
Externí odkaz:
https://doaj.org/article/5b81ee06ce51475396263d4d1ebb1da1
Autor:
Brian A. Baldo
Publikováno v:
Current Research in Toxicology, Vol 3, Iss , Pp 100078- (2022)
Respiratory depression (RD) is the primary cause of death due to opioids. Opioids bind to mu (µ)-opioid receptors (MORs) encoded by the MOR gene Oprm1, widely expressed in the central and peripheral nervous systems including centers that modulate br
Externí odkaz:
https://doaj.org/article/f081754c58cc48b8a4fc63339356e998
Autor:
Paulina M. Getsy, Santhosh M. Baby, Walter J. May, Tristan H.J. Lewis, James N. Bates, Yee-Hsee Hsieh, Benjamin Gaston, Stephen J. Lewis
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113277- (2022)
There is an urgent need for development of drugs that are able to reverse the adverse effects of opioids on breathing and arterial blood-gas (ABG) chemistry while preserving opioid analgesia. The present study describes the effects of bolus injection
Externí odkaz:
https://doaj.org/article/6ff878c2816540d6af32fc989e5eb70a
Akademický článek
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Publikováno v:
JA Clinical Reports, Vol 6, Iss 1, Pp 1-4 (2020)
Abstract Background Most children with trisomy 13 display central apnea, and are prone to opioid-induced respiratory depression. We conducted opioid-free anesthesia for a patient with trisomy 13 and obstructive sleep apnea, and safely extubated the p
Externí odkaz:
https://doaj.org/article/d02645b069aa45d3b182fd87a6649e4f
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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