Zobrazeno 1 - 10
of 80
pro vyhledávání: '"ophthalmic administration"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 804 (2024)
Lactoferrin (Lf), a multifunctional protein found abundantly in secretions, including tears, plays a crucial role in ocular health through its antimicrobial, immunoregulatory, anti-inflammatory, and antioxidant activities. Advanced delivery systems a
Externí odkaz:
https://doaj.org/article/83909bb9818e43848a6d0dea19ab1932
Publikováno v:
BMC Veterinary Research, Vol 18, Iss 1, Pp 1-13 (2022)
Abstract Background Canine keratoconjunctivitis sicca (KCS) is predominantly an immune-mediated disease. Current therapy of canine KCS is mainly by immunosuppressant, but the effectiveness was limited in some patients. In the past few years, some stu
Externí odkaz:
https://doaj.org/article/6051456c8f6c42fab8f6baebf480a342
Autor:
Ana Castro-Balado, Andrea Cuartero-Martínez, Hugo Pena-Verdeal, Gonzalo Hermelo-Vidal, Anja Schmidt, Belén Montero, Manuela Hernández-Blanco, Irene Zarra-Ferro, Miguel González-Barcia, Cristina Mondelo-García, María Jesús Giráldez, Eva Yebra-Pimentel, Francisco J. Otero-Espinar, Anxo Fernández-Ferreiro
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2589 (2023)
Background: Cystinosis is a rare genetic disorder characterized by the accumulation of cystine crystals in several tissues and organs causing, among others, severe eye symptoms. The high instability of cysteamine eye drops makes it difficult to devel
Externí odkaz:
https://doaj.org/article/271b0459a80f42a88df6a2a4e3b52f51
Autor:
Ana Castro-Balado, Enrique Bandín-Vilar, Andrea Cuartero-Martínez, Laura García-Quintanilla, Gonzalo Hermelo-Vidal, Xurxo García-Otero, Lorena Rodríguez-Martínez, Jesús Mateos, Manuela Hernández-Blanco, Pablo Aguiar, Irene Zarra-Ferro, Miguel González-Barcia, Cristina Mondelo-García, Francisco J. Otero-Espinar, Anxo Fernández-Ferreiro
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2194 (2022)
Cystinosis is a rare genetic disorder characterized by the accumulation of cystine crystals in different tissues and organs causing, among other symptoms, severe ocular manifestations. Cysteamine eye drops are prepared in hospital pharmacy department
Externí odkaz:
https://doaj.org/article/e65cc2c55cec4ea3b08449da511c4d45
Autor:
Raquel Gregorio Arribada, Francine Behar-Cohen, Andre Luis Branco de Barros, Armando Silva-Cunha
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1431 (2022)
The eye is an organ with limited drug access due to its anatomical and physiological barriers, and the usual forms of ocular administration are limited in terms of drug penetration, residence time, and bioavailability, as well as low patient complian
Externí odkaz:
https://doaj.org/article/82b7249988624926a02ef3b99efe486b
Autor:
Rubén Varela-Fernández, Xurxo García-Otero, Victoria Díaz-Tomé, Uxía Regueiro, Maite López-López, Miguel González-Barcia, María Isabel Lema, Francisco Javier Otero-Espinar
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 799 (2022)
Background: the present work describes the preparation, characterization and optimization of eight types of PLGA-based nanosystems (nanospheres and nanocapsules) as innovative mucoadhesive drug delivery systems of lactoferrin, in order to achieve a p
Externí odkaz:
https://doaj.org/article/ed0ce7ca83ee4f29a961f2bc4f94c639
Akademický článek
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Autor:
Xurxo García-Otero, Victoria Díaz-Tomé, Rubén Varela-Fernández, Manuel Martín-Pastor, Miguel González-Barcia, José Blanco-Méndez, Cristina Mondelo-García, Maria A. Bermudez, Francisco Gonzalez, Pablo Aguiar, Anxo Fernández-Ferreiro, Francisco J. Otero-Espinar
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 149 (2021)
Uveitis is a vision inflammatory disorder with a high prevalence in developing countries. Currently, marketed treatments remain limited and reformulation is usually performed to obtain a tacrolimus eye drop as a therapeutic alternative in corticoster
Externí odkaz:
https://doaj.org/article/870874844d6d4b1da97542204be64b6d
Autor:
Rubén Varela-Fernández, Xurxo García-Otero, Victoria Díaz-Tomé, Uxía Regueiro, Maite López-López, Miguel González-Barcia, María Isabel Lema, Francisco Javier Otero-Espinar
Publikováno v:
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
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Nanostructured lipid carriers (NLC) are novel lipidic nanosystems that provide significant improvements in terms of high drug loading capacity and controlled drug release. The purpose of the present work was based on the design, development, and phys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4044cd555899cb389a07776b5f73ccc2
https://doi.org/10.1016/j.ejpb.2022.02.010
https://doi.org/10.1016/j.ejpb.2022.02.010
Autor:
Ana Castro-Balado, Cristina Mondelo-García, Iria Varela-Rey, Beatriz Moreda-Vizcaíno, Jesús F. Sierra-Sánchez, María Teresa Rodríguez-Ares, Gonzalo Hermelo-Vidal, Irene Zarra-Ferro, Miguel González-Barcia, Eva Yebra-Pimentel, María Jesús Giráldez-Fernández, Francisco J. Otero-Espinar, Anxo Fernández-Ferreiro
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1177 (2020)
Cystinosis is a rare genetic disorder characterized by the accumulation of cystine crystals in different tissues and organs. Although renal damage prevails during initial stages, the deposition of cystine crystals in the cornea causes severe ocular m
Externí odkaz:
https://doaj.org/article/ea5ee06674bf431e91ea2d7063ef1c21