Zobrazeno 1 - 10
of 32 260
pro vyhledávání: '"open reading frame"'
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background Macular corneal dystrophy (MCD) is an inherited, autosomal recessive disorder of defective keratan sulfate (KS) metabolism. It is caused by the mutations in carbohydrate sulfotransferase 6 gene (CHST6) which is essential for the s
Externí odkaz:
https://doaj.org/article/1eb4634c396b4815b824417b1acabcfb
Autor:
Siti Kurniawati, Sri Winarsih, Sri Andarini, D. Rahmad Rizky, Rahmawati Ardiana, Waldy Yudha Perdana, Andrew Tulle
Publikováno v:
International Journal of One Health, Vol 10, Iss 2, Pp 178-182 (2024)
Background and Aim: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 1 million people and caused more than 100,000 deaths in Indonesia. This condition was augmented by a less advanced health system, especially in pr
Externí odkaz:
https://doaj.org/article/d0e47e62df6f461fac0710e0464d6c85
Autor:
Yaguang Zhang
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-33 (2024)
Abstract Long non-coding RNAs (lncRNAs), once considered transcriptional noise, have emerged as critical regulators of gene expression and key players in cancer biology. Recent breakthroughs have revealed that certain lncRNAs can encode small open re
Externí odkaz:
https://doaj.org/article/54b2c60c6c5f43b6a5957133edbe11c2
Autor:
Nechama Wieder, Elston N. D’Souza, Alexandra C. Martin-Geary, Frederik H. Lassen, Jonathan Talbot-Martin, Maria Fernandes, Sonia P. Chothani, Owen J. L. Rackham, Sebastian Schafer, Julie L. Aspden, Daniel G. MacArthur, Robert W. Davies, Nicola Whiffin
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Untranslated regions (UTRs) are important mediators of post-transcriptional regulation. The length of UTRs and the composition of regulatory elements within them are known to vary substantially across genes, but little is known ab
Externí odkaz:
https://doaj.org/article/419dbeb079c94514871454c4158e40f1
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 3, Pp 288-294 (2024)
Objective To explore the effect of open reading frame 66 (C12ORF66) located at chromosome 12 on the viability of MYCN amplified NB cell lines. Methods DDatasets GSE16476 and GSE49710 in R2 database were analyzed for expression level of C12ORF66 in MY
Externí odkaz:
https://doaj.org/article/963cb6313c11459ebf12eb0bffe30e93
Autor:
Zoya Shafat, Shama Parveen
Publikováno v:
Network Biology, Vol 14, Iss 1, Pp 25-37 (2024)
Hepatitis E virus (HEV) is the main cause of acute hepatitis worldwide. The viral infection caused by G1 HEV in pregnant women has become a major health concern in the past few years. The mechanism underlying the pathogenesis of viral infection in HE
Externí odkaz:
https://doaj.org/article/78297556ac874564b41eaba6e80fee15
Autor:
Toshiharu Ichinose, Shu Kondo, Mai Kanno, Yuichi Shichino, Mari Mito, Shintaro Iwasaki, Hiromu Tanimoto
Publikováno v:
eLife, Vol 12 (2024)
Multicellular organisms are composed of specialized cell types with distinct proteomes. While recent advances in single-cell transcriptome analyses have revealed differential expression of mRNAs, cellular diversity in translational profiles remains u
Externí odkaz:
https://doaj.org/article/a67569df7cc14c718ffb6880427faab9
Publikováno v:
Fujita Medical Journal, Vol 10, Iss 1, Pp 8-15 (2024)
Objectives: Taxonomic assignment based on whole-genome sequencing data facilitates clear demarcation of species within a complex genus. Here, we applied a unique pan-genome phylogenetic method, open reading frame (ORF)-based binarized structure netwo
Externí odkaz:
https://doaj.org/article/b95bfe587f3645c2a98bb75a0fdcc313
Publikováno v:
Porcine Health Management, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Background The wide diversity of porcine reproductive and respiratory syndrome virus (PRRSV) strains combined with incomplete heterologous cross-protection complicates the management of the disease at both the herd and the regional levels. T
Externí odkaz:
https://doaj.org/article/ece707ff734842688bb91e28b72b13e3