Zobrazeno 1 - 10
of 447
pro vyhledávání: '"oncomodulin"'
Akademický článek
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Publikováno v:
Poultry Science, Vol 103, Iss 8, Pp 103862- (2024)
ABSTRACT: Oncomodulins (OCMs), also known as non-α-parvalbumins, are small molecules known for their high-affinity binding of Ca2+ ions. They play crucial roles as Ca2+ buffers and participate in signaling pathways within muscle and neuron cells. In
Externí odkaz:
https://doaj.org/article/eb5779cec21e4a6c997462214d0e40ac
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 183 (2024)
The dysregulation of intracellular calcium levels is a critical factor in neurodegeneration, leading to the aberrant activation of calcium-dependent processes and, ultimately, cell death. Ca2+ signals vary in magnitude, duration, and the type of neur
Externí odkaz:
https://doaj.org/article/4ba46adeab984b9dbe607ffa632899f2
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15359 (2023)
Although most pathways in the mature central nervous system cannot regenerate when injured, research beginning in the late 20th century has led to discoveries that may help reverse this situation. Here, we highlight research in recent years from our
Externí odkaz:
https://doaj.org/article/abab08f94d9a4cb280b2327bd5a046c0
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
After a damaging insult, hair cells can spontaneously regenerate from cochlear supporting cells within the first week of life. While the regenerated cells express several markers of immature hair cells and have stereocilia bundles, their capacity to
Externí odkaz:
https://doaj.org/article/b2c9e533245c45c692aecab351a44c20
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Leslie K. Climer, Aubrey J. Hornak, Kaitlin Murtha, Yang Yang, Andrew M. Cox, Preston L. Simpson, Andy Le, Dwayne D. Simmons
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Ca2+ signaling is a major contributor to sensory hair cell function in the cochlea. Oncomodulin (OCM) is a Ca2+ binding protein (CaBP) preferentially expressed in outer hair cells (OHCs) of the cochlea and few other specialized cell types. Here, we e
Externí odkaz:
https://doaj.org/article/5f4612aa05074961beecf0eb0bd2d733
Autor:
Johannes M. Dijkstra, Yasuto Kondo
Publikováno v:
Biology, Vol 11, Iss 12, p 1713 (2022)
Parvalbumins are small molecules with important functions in Ca2+ signaling, but their sequence comparisons to date, especially in fish, have been relatively poor. We here, characterize sequence motifs that distinguish parvalbumin subfamilies across
Externí odkaz:
https://doaj.org/article/0ee6e7c57f2c4589923ae7a534df1375
Autor:
Kimberly A. Wong, Larry I. Benowitz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 10179 (2022)
The optic nerve, like most pathways in the mature central nervous system, cannot regenerate if injured, and within days, retinal ganglion cells (RGCs), the neurons that extend axons through the optic nerve, begin to die. Thus, there are few clinical
Externí odkaz:
https://doaj.org/article/40063cab330f4d47a241a054bad366ed
Autor:
Tong, Benton1, Hornak, Aubrey J.2, Maison, Stéphane F.3, Ohlemiller, Kevin K.1, Liberman, M. Charles3, Simmons, Dwayne D.2 dd.simmons@g.ucla.edu
Publikováno v:
Journal of Neuroscience. 2/3/2016, Vol. 36 Issue 5, p1631-1635. 5p.