Zobrazeno 1 - 10
of 54
pro vyhledávání: '"oncolytic virus (OV)"'
Akademický článek
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Autor:
Amirhossein Mardi, Anastasia V. Shirokova, Rebar N. Mohammed, Ali Keshavarz, Angelina O. Zekiy, Lakshmi Thangavelu, Talar Ahmad Merza Mohamad, Faroogh Marofi, Navid Shomali, Amir Zamani, Morteza Akbari
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-21 (2022)
Abstract Chimeric antigen receptor (CAR) T-cell therapy is a promising and rapidly expanding therapeutic option for a wide range of human malignancies. Despite the ongoing progress of CAR T-cell therapy in hematologic malignancies, the application of
Externí odkaz:
https://doaj.org/article/b4cc34ce3dae46dcbcf8d6c1e88007f8
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
According to the World Health Organization, cancer is one of the leading global health concerns, causing nearly 10 million deaths in 2020. While classical chemotherapeutics produce strong cytotoxicity on cancer cells, they carry limitations of drug r
Externí odkaz:
https://doaj.org/article/a73af356fc74434bbf462988799e83ff
Autor:
Jayeeta Ghose, Ada Dona, Mariam Murtadha, Emine Gulsen Gunes, Enrico Caserta, Ji Young Yoo, Luke Russell, Alena Cristina Jaime-Ramirez, Benjamin G. Barwick, Vikas A. Gupta, James F. Sanchez, Douglas W. Sborov, Steven T. Rosen, Amrita Krishnan, Lawrence H. Boise, Balveen Kaur, Craig C. Hofmeister, Flavia Pichiorri
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 519-531 (2021)
Because most patients with multiple myeloma (MM) develop resistance to current regimens, novel approaches are needed. Genetically modified, replication-competent oncolytic viruses exhibit high tropism for tumor cells regardless of cancer stage and pr
Externí odkaz:
https://doaj.org/article/65d17a0839584df484a779e3dc1740bf
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Talimogene laherparepvec (T-VEC) is a modified oncolytic herpes Simplex virus, type 1 (HSV-1) encoding granulocyte-macrophage colony stimulating factor (GM-CSF). T-VEC is adapted for selective replication in melanoma cells and GM-CSF was expressed to
Externí odkaz:
https://doaj.org/article/f95cca8078b04632a84b37342b1cb4d5
Autor:
Miaomiao Guo, Li Deng, Hongyang Liang, Yuyao Du, Wenrui Gao, Na Tian, Ying Bi, Jinghua Li, Tiancong Ma, Yuntao Zhang, Hui Wang
Publikováno v:
Viruses, Vol 15, Iss 1, p 178 (2023)
Oncolytic herpes simplex virus (oHSV) is a type of virus that selectively targets and kills cancer cells, leaving normal cells unharmed. Accurate viral titer is of great importance for the production and application of oHSV products. Droplet digital
Externí odkaz:
https://doaj.org/article/473715affcba48509c77fb9f5b18f1a9
Autor:
Iris Maria Forte, Paola Indovina, Serena Montagnaro, Aurora Costa, Carmelina Antonella Iannuzzi, Francesca Capone, Rosa Camerlingo, Anna Maria Malfitano, Francesca Pentimalli, Gianmarco Ferrara, Massimiliamo Quintiliani, Giuseppe Portella, Antonio Giordano, Roberto Ciarcia
Publikováno v:
Viruses, Vol 13, Iss 12, p 2458 (2021)
Malignant mesothelioma (MM) is an aggressive asbestos-related cancer, against which no curative modalities exist. Oncolytic virotherapy is a promising therapeutic approach, for which MM is an ideal candidate; indeed, the pleural location provides dir
Externí odkaz:
https://doaj.org/article/8f3394d13d974c7ca2da05c47c64a3d5
Publikováno v:
Translational Cancer Research
Background Cancer treatment remains one of the most formidable challenges worldwide. Some novel treatment strategies, including molecularly targeted therapy, gene therapy, and cellular immunotherapy, have also been investigated to improve therapeutic
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Vikas Gupta, Balveen Kaur, James F. Sanchez, Luke Russell, Ji Young Yoo, Steven T. Rosen, Alena Cristina Jaime-Ramirez, Enrico Caserta, Ada Dona, Jayeeta Ghose, Amrita Krishnan, Douglas W. Sborov, Emine Gulsen Gunes, Benjamin G. Barwick, Flavia Pichiorri, Mariam Murtadha, Lawrence H. Boise, Craig C. Hofmeister
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss, Pp 519-531 (2021)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Because most patients with multiple myeloma (MM) develop resistance to current regimens, novel approaches are needed. Genetically modified, replication-competent oncolytic viruses exhibit high tropism for tumor cells regardless of cancer stage and pr