Zobrazeno 1 - 10
of 57
pro vyhledávání: '"oncogenic signalling"'
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-16 (2021)
Abstract Background Narrow spectrum of action through limited molecular targets and unforeseen drug-related toxicities have been the main reasons for drug failures at the phase I clinical trials in complex diseases. Most plant-derived compounds with
Externí odkaz:
https://doaj.org/article/5a5f92ad2ebf412eab5a36cea2a1db9c
Autor:
Md Gulam Musawwir Khan, Amit Ghosh, Bhavesh Variya, Madanraj Appiya Santharam, Awais Ullah Ihsan, Sheela Ramanathan, Subburaj Ilangumaran
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-18 (2020)
Abstract Background SOCS1 and SOCS3 genes are considered tumor suppressors in hepatocellular carcinoma (HCC) due to frequent epigenetic repression. Consistent with this notion, mice lacking SOCS1 or SOCS3 show increased susceptibility to diethylnitro
Externí odkaz:
https://doaj.org/article/b0c8476559ed426cbe28a38d451c4be5
Autor:
Frederik J. Verweij, Cecilia de Heus, Stefanie Kroeze, Houjian Cai, Elliott Kieff, Sander R. Piersma, Connie R. Jimenez, Jaap M. Middeldorp, Dirk Michiel Pegtel
Publikováno v:
Journal of Extracellular Vesicles, Vol 4, Iss 0, Pp 1-12 (2015)
The Epstein–Barr virus (EBV)-encoded oncoprotein latent membrane protein 1 (LMP1) constitutively activates nuclear factor κB (NFκB) from intracellular membranes to promote cell growth and survival. LMP1 associates with CD63 in intracellular membr
Externí odkaz:
https://doaj.org/article/b555fe7874e5439fa6b50d2f96aeff7d
Akademický článek
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Autor:
Jason P. Holland
Publikováno v:
CHIMIA, Vol 70, Iss 11 (2016)
Functional molecular imaging provides a unique perspective on a disease. Methods including positron-emission tomography and magnetic resonance imaging allow us to interrogate spatial and temporal changes in biomarkers as well as probe the underlying
Externí odkaz:
https://doaj.org/article/9aafe7e3a9044577aa7359a52b887687
Autor:
Ingrid Grozavu, Sarah Stuart, Anna Lyakisheva, Zhong Yao, Shivanthy Pathmanathan, Michael Ohh, Igor Stagljar
KRAS is one of the most frequently mutated oncogenes in human cancers. Despite nearly 40 years of research, KRAS remains largely undruggable, in part due to an incomplete understanding of its biology. Recently, KRAS dimerization was discovered to pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b466c68e5d19e1f115f1b48e10a2ad05
https://www.bib.irb.hr/1242103
https://www.bib.irb.hr/1242103
Autor:
Abdul Mannan, Janis Chamberlain, Brett Nixon, Matthew D. Dun, Jonathan R. Sillar, Zacary P. Germon
Publikováno v:
Antioxidants, Vol 10, Iss 1616, p 1616 (2021)
Antioxidants
Antioxidants
Acute lymphoblastic leukaemia (ALL) is the most common cancer diagnosed in children and adolescents. Approximately 70% of patients survive >5-years following diagnosis, however, for those that fail upfront therapies, survival is poor. Reactive oxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b986e6b8fcf3b53246d376672a28ab70
https://www.mdpi.com/2076-3921/10/10/1616
https://www.mdpi.com/2076-3921/10/10/1616
Autor:
Awais Ullah Ihsan, Amit Ghosh, Sheela Ramanathan, Bhavesh C. Variya, Gulam Musawwir Khan, Madanraj Appiya Santharam, Subburaj Ilangumaran
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-18 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-18 (2020)
Background SOCS1 and SOCS3 genes are considered tumor suppressors in hepatocellular carcinoma (HCC) due to frequent epigenetic repression. Consistent with this notion, mice lacking SOCS1 or SOCS3 show increased susceptibility to diethylnitrosamine (D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9bc851725d5c478027900b9e529f78
https://pubmed.ncbi.nlm.nih.gov/32807134
https://pubmed.ncbi.nlm.nih.gov/32807134
Akademický článek
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Akademický článek
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