Zobrazeno 1 - 10
of 418
pro vyhledávání: '"oncogene-induced senescence"'
Publikováno v:
Cells, Vol 13, Iss 14, p 1215 (2024)
Pediatric low-grade gliomas (PLGGs) comprise a heterogeneous set of low-grade glial and glioneuronal tumors, collectively representing the most frequent CNS tumors of childhood and adolescence. Despite excellent overall survival rates, the chronic na
Externí odkaz:
https://doaj.org/article/162838ea0f524b0aadf96adc18bbc27c
Autor:
Andreas Domen, Christophe Deben, Jasper Verswyvel, Tal Flieswasser, Hans Prenen, Marc Peeters, Filip Lardon, An Wouters
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-35 (2022)
Abstract Cellular senescence is a state of stable cell-cycle arrest with secretory features in response to cellular stress. Historically, it has been considered as an endogenous evolutionary homeostatic mechanism to eliminate damaged cells, including
Externí odkaz:
https://doaj.org/article/b64cfeae058642f8a5d74c8b1aeb8c07
Autor:
Laura Bousset, Jesús Gil
Publikováno v:
Molecular Oncology, Vol 16, Iss 21, Pp 3855-3880 (2022)
Cellular senescence is a stress response elicited by different molecular insults. Senescence results in cell cycle exit and is characterised by multiple phenotypic changes such as the production of a bioactive secretome. Senescent cells accumulate du
Externí odkaz:
https://doaj.org/article/2ca5baeea02446129175668e8e7b005b
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Cellular senescence plays a complicated and vital role in cancer development because of its divergent effects on tumorigenicity. However, the long non-coding RNAs (lncRNAs) associated with tumor senescence and their prognostic value in he
Externí odkaz:
https://doaj.org/article/419c213bc69f4d0d99b8bc256f699c8d
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-7 (2020)
Abstract There are two kinds of condensins in human cells, known as condensin I and condensin II. The canonical roles of condensins are participated in chromosome dynamics, including chromosome condensation and segregation during cell division. Recen
Externí odkaz:
https://doaj.org/article/36756f48cf404b029429c29de4d43b44
Autor:
Rodrigo E. Cáceres-Gutiérrez, Yair Alfaro-Mora, Marco A. Andonegui, José Díaz-Chávez, Luis A. Herrera
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
RAS oncogenes are chief tumorigenic drivers, and their mutation constitutes a universal predictor of poor outcome and treatment resistance. Despite more than 30 years of intensive research since the identification of the first RAS mutation, most atte
Externí odkaz:
https://doaj.org/article/94c381212319473f976093c5ec128c6f
Autor:
Mara Mazzoni, Giuseppe Mauro, Marco Erreni, Paola Romeo, Emanuela Minna, Maria Grazia Vizioli, Cristina Belgiovine, Maria Grazia Rizzetti, Sonia Pagliardini, Roberta Avigni, Maria Chiara Anania, Paola Allavena, Maria Grazia Borrello, Angela Greco
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Abstract Background Thyroid carcinoma includes several variants characterized by different biological and clinical features: from indolent microcarcinoma to undifferentiated and aggressive anaplastic carcinoma. Inflammation plays a critical role in t
Externí odkaz:
https://doaj.org/article/95caeb225f714bf98d84e023062636ff
Autor:
Cristine Ding, Tarik Tihan
Publikováno v:
Balkan Medical Journal, Vol 36, Iss 1, Pp 3-11 (2019)
Pilocytic and pilomyxoid astrocytomas are some of the most common gliomas in children and young adults. These gliomas are indolent neoplasms with long overall survival probability. The genetic characteristics of these neoplasms are well known, and ou
Externí odkaz:
https://doaj.org/article/d2beaed965dd419e91660b0f5396e4db
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Akademický článek
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