Detecting Selection in the HIV-1 Genome during Sexual Transmission Events

Autor: David Seifert, Beda Joos, Dominique L. Braun, Corinna S. Oberle, Corinne D. Schenkel, Herbert Kuster, Christina Grube, Jürg Böni, Sabine Yerly, Vincent Aubert, Thomas Klimkait, Huldrych F. Günthard, Niko Beerenwinkel, Karin J. Metzner, on behalf of the Swiss HIV Cohort Study

Publikováno v: Viruses, Vol 14, Iss 2, p 406 (2022)

Little is known about whether and how variation in the HIV-1 genome affects its transmissibility. Assessing which genomic features of HIV-1 are under positive or negative selection during transmission is challenging, because very few virus particles

Externí odkaz: https://doaj.org/article/a2d2a2e73e1c475f92e18d04fcf25821

Detecting Selection in the HIV-1 Genome during Sexual Transmission Events

Autor: Study, David Seifert, Beda Joos, Dominique L. Braun, Corinna S. Oberle, Corinne D. Schenkel, Herbert Kuster, Christina Grube, Jürg Böni, Sabine Yerly, Vincent Aubert, Thomas Klimkait, Huldrych F. Günthard, Niko Beerenwinkel, Karin J. Metzner, on behalf of the Swiss HIV Cohort Study on behalf of the Swiss HIV Cohort

Publikováno v: Viruses; Volume 14; Issue 2; Pages: 406

Little is known about whether and how variation in the HIV-1 genome affects its transmissibility. Assessing which genomic features of HIV-1 are under positive or negative selection during transmission is challenging, because very few virus particles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::b9c5068b67ed1a00e4dd0ff690758938

Real-Life Therapeutic Concentration Monitoring of Long-Acting Cabotegravir and Rilpivirine: Preliminary Results of an Ongoing Prospective Observational Study in Switzerland.

Autor: Thoueille P; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland., Alves Saldanha S; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland., Schaller F; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland., Munting A; Service of Infectious Diseases, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland., Cavassini M; Service of Infectious Diseases, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland., Braun D; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, 8091 Zurich, Switzerland.; Institute of Medical Virology, University of Zurich, 8057 Zurich, Switzerland., Günthard HF; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, 8091 Zurich, Switzerland.; Institute of Medical Virology, University of Zurich, 8057 Zurich, Switzerland., Kusejko K; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, 8091 Zurich, Switzerland.; Institute of Medical Virology, University of Zurich, 8057 Zurich, Switzerland., Surial B; Department of Infectious Diseases, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland., Furrer H; Department of Infectious Diseases, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland., Rauch A; Department of Infectious Diseases, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland., Ustero P; Division of Infectious Diseases, Faculty of Medicine, Geneva University Hospitals, 1205 Geneva, Switzerland., Calmy A; Division of Infectious Diseases, Faculty of Medicine, Geneva University Hospitals, 1205 Geneva, Switzerland.; Department of Medicine, Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland., Stoeckle M; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland., Battegay M; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.; Faculty of Medicine, University of Basel, 4031 Basel, Switzerland., Marzolini C; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.; Faculty of Medicine, University of Basel, 4031 Basel, Switzerland.; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3GF, UK., Andre P; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland., Guidi M; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.; Centre for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, 1206 Geneva, Switzerland., Buclin T; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland., Decosterd LA; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland., On Behalf Of The Swiss Hiv Cohort Study

Publikováno v: Pharmaceutics [Pharmaceutics] 2022 Jul 29; Vol. 14 (8). Date of Electronic Publication: 2022 Jul 29.