Zobrazeno 1 - 10
of 19
pro vyhledávání: '"on behalf of the NCER-PD"'
Autor:
Cyril Brzenczek, Quentin Klopfenstein, Tom Hähnel, Holger Fröhlich, Enrico Glaab, On behalf of the NCER-PD Consortium
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Parkinson’s disease (PD) presents diverse symptoms and comorbidities, complicating its diagnosis and management. The primary objective of this cross-sectional, monocentric study was to assess digital gait sensor data’s utility for monito
Externí odkaz:
https://doaj.org/article/2154a18734524380bf834cce4dc9d329
Autor:
Velma T. E. Aho, Matthias Klee, Zied Landoulsi, Anna Heintz-Buschart, Lukas Pavelka, Anja K. Leist, Rejko Krüger, Patrick May, Paul Wilmes, on behalf of the NCER-PD Consortium
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-6 (2024)
Abstract Gut microbiome differences between people with Parkinson’s disease (PD) and control subjects without Parkinsonism are widely reported, but potential alterations related to PD with mild cognitive impairment (MCI) have yet to be comprehensiv
Externí odkaz:
https://doaj.org/article/897dee69227047e585ed34f6bcedcc9f
Autor:
Elisa Gómez de Lope, Rebecca Ting Jiin Loo, Armin Rauschenberger, Muhammad Ali, Lukas Pavelka, Tainá M. Marques, Clarissa P. C. Gomes, Rejko Krüger, Enrico Glaab, On behalf of the NCER-PD Consortium
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-18 (2024)
Abstract Parkinson’s disease (PD) is a highly heterogeneous disorder influenced by several environmental and genetic factors. Effective disease-modifying therapies and robust early-stage biomarkers are still lacking, and an improved understanding o
Externí odkaz:
https://doaj.org/article/b8ad0431f7b84cecb8dda564ad5437a9
Autor:
Sinthuja Pachchek, Zied Landoulsi, Lukas Pavelka, Claudia Schulte, Elena Buena-Atienza, Caspar Gross, Ann-Kathrin Hauser, Dheeraj Reddy Bobbili, Nicolas Casadei, Patrick May, Rejko Krüger, on behalf of the NCER-PD Consortium
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Heterozygous variants in the glucocerebrosidase GBA1 gene are an increasingly recognized risk factor for Parkinson’s disease (PD). Due to the GBAP1 pseudogene, which shares 96% sequence homology with the GBA1 coding region, accurate varian
Externí odkaz:
https://doaj.org/article/7718d5c32af844e6882c7b60f9c51e58
Autor:
Lukas Pavelka, Rajesh Rawal, Soumyabrata Ghosh, Claire Pauly, Laure Pauly, Anne-Marie Hanff, Pierre Luc Kolber, Sonja R. Jónsdóttir, Deborah Mcintyre, Kheira Azaiz, Elodie Thiry, Liliana Vilasboas, Ekaterina Soboleva, Marijus Giraitis, Olena Tsurkalenko, Stefano Sapienza, Nico Diederich, Jochen Klucken, Enrico Glaab, Gloria A. Aguayo, Eduardo Rosales Jubal, Magali Perquin, Michel Vaillant, Patrick May, Manon Gantenbein, Venkata P. Satagopam, Rejko Krüger, on behalf of the NCER-PD Consortium
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundDeep phenotyping of Parkinson’s disease (PD) is essential to investigate this fastest-growing neurodegenerative disorder. Since 2015, over 800 individuals with PD and atypical parkinsonism along with more than 800 control subjects have be
Externí odkaz:
https://doaj.org/article/8f31585bf83f4c7e80c470afa0d9d004
Autor:
Sinthuja Pachchek, Zied Landoulsi, Lukas Pavelka, Claudia Schulte, Elena Buena-Atienza, Caspar Gross, Ann-Kathrin Hauser, Dheeraj Reddy Bobbili, Nicolas Casadei, Patrick May, Rejko Krüger, on behalf of the NCER-PD Consortium
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/7ccab39398664c0ebd41162387c282c1
Autor:
L. Pavelka, A. Rauschenberger, Z. Landoulsi, S. Pachchek, P. May, E. Glaab, R. Krüger, on behalf of the NCER-PD Consortium
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Several phenotypic differences observed in Parkinson’s disease (PD) patients have been linked to age at onset (AAO). We endeavoured to find out whether these differences are due to the ageing process itself by using a combined dataset of i
Externí odkaz:
https://doaj.org/article/722493723e69462cb404f9b8182a7585
Autor:
Shubhra Acharya, Andrew I. Lumley, Lu Zhang, Mélanie Vausort, Yvan Devaux, on behalf of the NCER-PD Consortium
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10040 (2023)
Finding novel biomarkers for Parkinson’s disease (PD) is crucial for early disease diagnosis, severity assessment and identifying novel disease-modifying drug targets. Our study aimed at investigating the GATA3 mRNA levels in whole blood samples of
Externí odkaz:
https://doaj.org/article/6b6ea60a3e9e472f8f3b120cc3cf4376
Autor:
Federico Baldini, Johannes Hertel, Estelle Sandt, Cyrille C. Thinnes, Lorieza Neuberger-Castillo, Lukas Pavelka, Fay Betsou, Rejko Krüger, Ines Thiele, on behalf of the NCER-PD Consortium
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-21 (2020)
Abstract Background Parkinson’s disease (PD) is a systemic disease clinically defined by the degeneration of dopaminergic neurons in the brain. While alterations in the gut microbiome composition have been reported in PD, their functional consequen
Externí odkaz:
https://doaj.org/article/10f7f75169714d4592bd339f6cfa3dd1
Autor:
L. Pavelka, A. Rauschenberger, Z. Landoulsi, S. Pachchek, P. May, E. Glaab, R. Krüger, on behalf of the NCER-PD Consortium
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/7bda97220d124795acf3b6d7a9ac5b1e