Zobrazeno 1 - 10
of 10 471
pro vyhledávání: '"oestrogen"'
Autor:
Victor Oghenekparobo Emojevwe, Mega Obukohwo Oyovwi, Kayode Ezekiel Adewole, Peggy Ejiro Ohwin, Adeniran Oluwadamilare Akinola, Alexander Obidike Naiho, Eze Kingsley Nwangwa, Victor Omo-Idonije, Motunrayo Lade-Ige, Benneth Ben-Azu
Publikováno v:
Asian Pacific Journal of Reproduction, Vol 13, Iss 5, Pp 228-240 (2024)
Objective: To investigate the potential of N-acetylcysteine (NAC) and zinc sulphate (ZnSO4) in mitigating reproductive dysfunction caused by di-2-ethylhexyl phthalate (DEHP) in rats and to understand the underlying mechanisms, specifically oxidative
Externí odkaz:
https://doaj.org/article/94801eb6ea7d4aa3b60a09998e3eff2b
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 10, Pp 06-10 (2024)
Introduction: In breast carcinoma, a panel of various marker proteins are used to characterise tumour subtypes, confirm tissue of origin, distinguish metastatic tumours from primary tumours, and provide additional information that may be important fo
Externí odkaz:
https://doaj.org/article/655a622644ea4d8b985a6d91cfe80917
Resveratrol activates MAPK/ERK pathway to regulate oestrogen metabolism in type I endometrial cancer
Autor:
Qing Wang, Jia-yun Zhou, Li Liu, Ze-yuan Yin, Yan-yu Li, Meng Wang, Jing-bo Zhang, Hui Lu, Xue-yan Zhou, Bei Zhang
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Objective Endometrial cancer (EC) is an oestrogen-dependent tumour, the occurrence of which is closely related to an imbalance of oestrogen homeostasis. Our previous studies explored the effects of Resveratrol(Res) on oestrogen metabolism. H
Externí odkaz:
https://doaj.org/article/0756a64301524942817d10caae961829
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 497-503 (2024)
Introduction: Rare cancers, in aggregate, represent a significant burden of disease in oncology and remain therapeutically challenging to manage due to a lack of clinical trials. Eccrine porocarcinoma is a rare cutaneous sweat-gland malignancy for wh
Externí odkaz:
https://doaj.org/article/02ce1788b67b4acc931f4c5021497667
Autor:
Ka-Liong Tan, Syed Haider, Christos E. Zois, Jianting Hu, Helen Turley, Russell Leek, Francesca Buffa, Oreste Acuto, Adrian L. Harris, Francesco Pezzella
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102106- (2024)
Current prognostic biomarkers fall short in stratifying Oestrogen receptor (ER)-negative breast cancer patients regarding tumour progression risk at diagnosis. The role of AIPL1 in activating its tumour suppressor client protein, NEDD8 Ultimate Buste
Externí odkaz:
https://doaj.org/article/9929b2fc3b5b4dfba1631ace026e5e2e
Autor:
Eline JH van Houtum, Anne HC Valk, Daniel Granado, Jasper Lok, Lune van den Bogaard, Naomi Remkes, Jesper van Eck van der Sluijs, Paul N Span, Lenneke AM Cornelissen, Gosse J Adema
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 9, Pp n/a-n/a (2024)
Abstract Objectives PD‐1/PD‐L1 immune checkpoint blockade can be an effective treatment for advanced breast cancer patients. However, patients with oestrogen receptor positive (ER+) tumors often display only low lymphocyte infiltration, while a l
Externí odkaz:
https://doaj.org/article/c10814c5d7244fc29c3f29ede665bafe
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 1-20 (2024)
Externí odkaz:
https://doaj.org/article/256c91312718416188fb414b89e6df2e
Publikováno v:
Polish Journal of Pathology, Vol 75, Iss 1, Pp 8-18 (2024)
The use of chemotherapy in breast cancer management has significantly contributed to the decrease in its mortality. Currently, the prognosis is determined by molecular biomarkers, such as oestrogen receptors, and human epidermal growth factor recepto
Externí odkaz:
https://doaj.org/article/d8877dcf9a8743adbc10d3f30f07181b
Publikováno v:
Arhiv za Higijenu Rada i Toksikologiju, Vol 75, Iss 1, Pp 68-75 (2024)
Environmental pollution with plastic nanoparticles (PNPs) has rendered hazard assessment of unintentional human exposure to neurotherapeutic drugs through contaminated water and food ever more complicated. Due to their small size, PNPs can easily ent
Externí odkaz:
https://doaj.org/article/0e6dbf67484a4d12b5c6fece4173da74
Autor:
Geriolda Topi, Shakti Ranjan Satapathy, Souvik Ghatak, Karin Hellman, Fredrik Ek, Roger Olsson, Roy Ehrnström, Marie-Louise Lydrup, Anita Sjölander
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon carcinomas, the ERα/β ratio is often increased, an observation t
Externí odkaz:
https://doaj.org/article/9909d49bdbe2475eb75229dbd8eb2454