Zobrazeno 1 - 10
of 197
pro vyhledávání: '"ocular therapy"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 10, p 1325 (2024)
Eye disorders affect a substantial portion of the global population, yet the availability of efficacious ophthalmic drug products remains limited. This can be partly ascribed to a number of factors: (1) inadequate understanding of physiological barri
Externí odkaz:
https://doaj.org/article/f124cc13953145e8a6da4c6ac39c0401
Publikováno v:
Bioengineering, Vol 11, Iss 2, p 179 (2024)
Ocular diseases present a unique challenge and opportunity for therapeutic development. The eye has distinct advantages as a therapy target given its accessibility, compartmentalization, immune privilege, and size. Various methodologies for therapeut
Externí odkaz:
https://doaj.org/article/fd56c8305f874fadb70a162095cc027e
Autor:
Hyeonah Lee, Hyeran Noh
Publikováno v:
Gels, Vol 9, Iss 9, p 718 (2023)
Nanomedicine in gel or particle formation holds considerable potential for enhancing passive and active targeting within ocular drug delivery systems. The complex barriers of the eye, exemplified by the intricate network of closely connected tissue s
Externí odkaz:
https://doaj.org/article/00a3fe6a274d473282c44ae581ef40f1
Akademický článek
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Autor:
Maha M. Abdallah, Inês C. Leonardo, Luna Krstić, Amalia Enríquez-de-Salamanca, Yolanda Diebold, María J. González-García, Frédéric B. Gaspar, Ana A. Matias, Maria Rosário Bronze, Naiara Fernández
Publikováno v:
Foods, Vol 11, Iss 3, p 342 (2022)
A green technique was developed to extract hyaluronic acid (HA) from tuna vitreous humor (TVH) for its potential application in managing dry eye disease. Deep eutectic solvents (DES) were used to extract HA and were synthesized using natural compound
Externí odkaz:
https://doaj.org/article/a93d99ae22cd4937a8fdd74f93ea97d6
Akademický článek
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Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1528 (2021)
Rhodopsin (RHO) misfolding mutations are a common cause of the blinding disease autosomal dominant retinitis pigmentosa (adRP). The most prevalent mutation, RHOP23H, results in its misfolding and retention in the endoplasmic reticulum (ER). Under hom
Externí odkaz:
https://doaj.org/article/e6792afba021481f827147a1e8f40675
Autor:
Razwa Saleh, Hasan Mahmud Reza
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-9 (2017)
Abstract Background The human umbilical cord has been studied extensively in the past two decades. It is free of ethical dilemmas, non-tumorigenic, and less immunogenic and thus provides a significant advantage over other stem cell sources. The cord
Externí odkaz:
https://doaj.org/article/a5598823b53d4f9ca5eff3ecb96260e8
Efficient Ocular Delivery of VCP siRNA via Reverse Magnetofection in RHO P23H Rodent Retina Explants
Autor:
Merve Sen, Marco Bassetto, Florent Poulhes, Olivier Zelphati, Marius Ueffing, Blanca Arango-Gonzalez
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 225 (2021)
The use of synthetic RNA for research purposes as well as RNA-based therapy and vaccination has gained increasing importance. Given the anatomical seclusion of the eye, small interfering RNA (siRNA)-induced gene silencing bears great potential for ta
Externí odkaz:
https://doaj.org/article/de8efd1e5ac248dea2527da61eedeabb
Publikováno v:
Microorganisms, Vol 7, Iss 10, p 429 (2019)
Herpes simplex virus type-1 (HSV-1) is a neurotropic, double-stranded DNA virus that can cause a wide variety of diseases, including many ocular pathologies. It is one of the leading causes of infectious blindness in the United States. Because of its
Externí odkaz:
https://doaj.org/article/4e00046fdbfe4c9a9cec9703781c194a