Third harmonic generation imaging for fast, label-free pathology of human brain tumors

Autor: Pieter Wesseling, Huibert D. Mansvelder, Johannes C. Baayen, Nikolay V. Kuzmin, G. D. Galgano, P. C. de Witt Hamer, Marie Louise Groot, David P. Noske

Publikováno v: Kuzmin, N V, Wesseling, P, Hamer, P C D, Noske, D P, Galgano, G, Mansvelder, H D, Baayen, J C & Groot, M L 2016, ' Third harmonic generation imaging for fast, label-free pathology of human brain tumors ', Biomedical Optics Express, no. 7, 5, pp. 1889-1904 . https://doi.org/10.1364/BOE.7.001889
Biomedical Optics Express, 7, 5, pp. 1889-904
ResearcherID
Kuzmin, N V, Wesseling, P, Hamer, P C D W, Noske, D P, Galgano, G D, Mansvelder, H D, Baayen, J C & Groot, M L 2016, ' Third harmonic generation imaging for fast, label-free pathology of human brain tumors ', Biomedical Optics Express, vol. 7, no. 5, pp. 1889-1904 . https://doi.org/10.1364/BOE.7.001889
Biomedical Optics Express
Biomedical Optics Express, 7, 1889-904
Biomedical Optics Express, 7(5), 1889-1904. The Optical Society
Biomedical Optics Express, 1889-1904. The Optical Society
ISSUE=7;STARTPAGE=1889;ENDPAGE=1904;ISSN=2156-7085;TITLE=Biomedical Optics Express
Biomedical optics express, 7(5), 1889. The Optical Society

Contains fulltext : 171797.pdf (Publisher’s version ) (Open Access) In brain tumor surgery, recognition of tumor boundaries is key. However, intraoperative assessment of tumor boundaries by the neurosurgeon is difficult. Therefore, there is an urge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c3bb2cee0193dcfcb649f87bd9949c
https://hdl.handle.net/1871.1/c5b1da0b-e4f7-417e-9776-53acfd6303e5

Gradient field microscopy of unstained specimens

Autor: Gabriel Popescu, Shamira Sridharan, Taewoo Kim

Publikováno v: Optics Express

We present a phase derivative microscopy technique referred to as gradient field microscopy (GFM), which provides the first-order derivatives of the phase associated with an optical field passing through a transparent specimen. GFM utilizes spatial l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1422b22348d01b5c64eb6b66abbae9ca
http://europepmc.org/articles/PMC3482907

Optical imaging of metabolism in HER2 overexpressing breast cancer cells

Autor: Brent N. Rexer, Alex J. Walsh, Melissa C. Skala, Carlos L. Arteaga, Rebecca S. Cook

Publikováno v: Biomedical Optics Express

The optical redox ratio (fluorescence intensity of NADH divided by that of FAD), was acquired for a panel of breast cancer cell lines to investigate how overexpression of human epidermal growth factor receptor 2 (HER2) affects tumor cell metabolism,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842e4be1ec6198032c0cf5da9ba598e0
http://europepmc.org/articles/PMC3255344

Single-shot Full-field reflection phase microscopy

Autor: Zahid Yaqoob, Toyohiko Yamauchi, Wonshik Choi, Dan Fu, Ramachandra R. Dasari, Michael S. Feld

Publikováno v: Optics Express

The present invention relates to a full-field reflection phase microscope. In a preferred embodiment, the invention can combine low-coherence interferometry and off-axis digital holographic microscopy (DHM). The reflection-based DHM provides highly s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24c39f9c03b003d7dba2c6533561c82
http://europepmc.org/articles/PMC3368324

Quantifying subcellular dynamics in apoptotic cells with two-dimensional Gabor filters

Autor: Jing-Yi Zheng, Nada N. Boustany, Bryan Rabin, Robert M. Pasternack

Publikováno v: Biomedical Optics Express

We demonstrate an optical Fourier filtering method which can be used to characterize subcellular morphology during dynamic cellular function. In this paper, our Fourier filters were based on two-dimensional Gabor elementary functions, which can be tu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a4a2d87700aeb8b96d6c96a34a8911
http://europepmc.org/articles/PMC3018000