Zobrazeno 1 - 10
of 2 273
pro vyhledávání: '"objective response"'
Autor:
Natale Quartuccio, Vincenzo Militano, Marco Pappalardo, Luca Filippi, Oreste Bagni, Antonino Maria Moreci, Salvatore Ialuna
Publikováno v:
Current Oncology, Vol 31, Iss 11, Pp 6879-6890 (2024)
Aim: To meta-analyze the utility of transarterial radioembolization (TARE) in patients with liver metastatic breast cancer (BC), based on the objective response rate (ORR) and disease control rate (DCR). Methods: A literature search was performed ret
Externí odkaz:
https://doaj.org/article/d7bcbc509f354925a3ae265928d1de4f
Autor:
Junaid Anwar, Hafiz Muhammad Arslan, Zouina Sarfraz, Juwairiya Shuroog, Ahmed Abdelhakeem, Ali Saeed, Anwaar Saeed
Publikováno v:
Current Oncology, Vol 31, Iss 11, Pp 7204-7225 (2024)
Background: Hepatocellular carcinoma (HCC) is a prevalent liver cancer with poor prognosis, often linked to hepatitis B (HBV) and C (HCV) infections. This meta-analysis evaluates the efficacy of immunotherapy in HCC, particularly in cases arising fro
Externí odkaz:
https://doaj.org/article/bedc4954cf7842f9a663f2a8a8f4b252
Autor:
Aram A. Musaelyan, Svetlana V. Odintsova, Karina A. Musaelyan, Magaripa A. Urtenova, Ekaterina P. Solovyova, Lyubov I. Menshikova, Sergey V. Orlov
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 5, Iss 6, Pp 1271-1288 (2024)
Aim: The present study aims to evaluate the efficacy of rechallenge with immune checkpoint inhibitors (ICIs) compared to chemotherapy and the predictive role of clinical parameters in non-small cell lung cancer (NSCLC) patients who were rechallenged.
Externí odkaz:
https://doaj.org/article/8225d2e5d73e42368811cf2a42c055c3
Autor:
Nini Aung, Margaret Bowers, Gillian Brearton, Andrew Charlton, Joanne Craig, Jonathan Cullis, Ray Dang, David Donaldson, Mary Drake, Rachel Hall, Elizabeth Parkins, Jane Tighe, Ceri Bygrave, Oonagh Sheehy
Publikováno v:
eJHaem, Vol 5, Iss 5, Pp 987-991 (2024)
Abstract This report describes the characteristics and outcomes of 18 heavily pretreated patients with multiple myeloma (MM) who were subsequently treated with selinexor. This is a case series of 18 patients with MM who were treated with selinexor an
Externí odkaz:
https://doaj.org/article/456cfae128ad4e339dda45d427858acc
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract In oncology anti—PD1 / PDL1 therapy development for solid tumors, objective response rate (ORR) is commonly used clinical endpoint for early phase study decision making, while progression free survival (PFS) and overall survival (OS) are w
Externí odkaz:
https://doaj.org/article/2fcb5d71d6c540c39d5d70e19e351802
Autor:
Jaejun Lee, Jae-Sung Yoo, Ji Hoon Kim, Dong Yeup Lee, Keungmo Yang, Bohyun Kim, Joon-Il Choi, Jeong Won Jang, Jong Young Choi, Seung Kew Yoon, Ji Won Han, Pil Soo Sung
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundProgrammed death-ligand 1 (PD-L1) expression is abundant not only in malignant cells but also in infiltrating cells within the tumor microenvironment (TME) of hepatocellular carcinoma (HCC). This study explored the association between PD-L1
Externí odkaz:
https://doaj.org/article/61e9993b246344419c80a07a53efe92b
Autor:
Yi-Ming Ma, Shu-Xia Cheng, Ming-Chuan Zhang, Hui-Ying Zhang, Jun-Jiao Gu, Pan-Pan Zhao, Hong Ge
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeThis study compared the timing effects of immune checkpoint inhibitor (ICIs) administration on the efficacy and safety of concurrent chemoradiotherapy for cervical cancer.MethodsThis study included patients with advanced cervical cancer who re
Externí odkaz:
https://doaj.org/article/9c02e653dcee4dda9904616d816432b9
Autor:
Renming Huang, Feng Ji, Leyi Huang, Yueying Qin, Zhiyu Liang, Miaoyan Huang, Chunyan Li, Jian Ban
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionThis meta-analysis was performed to evaluate the efficacy and safety of angiogenesis inhibitors (Ais) combined with poly ADP ribose polymerase inhibitors (PARPi) in the maintenance treatment of advanced ovarian cancer (OC).Materials and m
Externí odkaz:
https://doaj.org/article/1be85c1c3e3f42b8841fe253b0dc22c0
Autor:
Haitian LI, Qing LIU, Bin LI, Yuzhen CHEN, Junping LIN, Yuqi MENG, Haiming FENG, Zhizhong ZHENG, Yiming HUI
Publikováno v:
Chinese Journal of Lung Cancer, Vol 27, Iss 6, Pp 421-430 (2024)
Background and objective Lung cancer is the cancer with the highest incidence and mortality rates in China, and non-small cell lung cancer (NSCLC) accounts for 80%-85% of all malignant lung tumors. Currently, surgical treatment remains the primary tr
Externí odkaz:
https://doaj.org/article/f24a54f5768d4df39e5475bb00eb50ae
Publikováno v:
Zhongguo linchuang yanjiu, Vol 37, Iss 5, Pp 756-759 (2024)
Objective To compare the efficacy and safety of programmed cell death protein 1 (PD-1) inhibitor + albumin paclitaxel and platinum + PD-1 inhibitor + albumin-paclitaxel in the treatment of advanced metastasis or recurrent cervical cancer. Methods The
Externí odkaz:
https://doaj.org/article/18a0d6764a0a4a9f90a5f2313f580d91