Zobrazeno 1 - 10
of 2 295
pro vyhledávání: '"ob/ob mice"'
Autor:
Yiming Ding, Xulei Dai, Miaoye Bao, Yuanming Xing, Junhui Liu, Sihai Zhao, Enqi Liu, Zuyi Yuan, Liang Bai
Publikováno v:
Animal Models and Experimental Medicine, Vol 6, Iss 4, Pp 317-328 (2023)
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is the main reason for cirrhosis and hepatocellular carcinoma. As a starting point for NAFLD, the treatment of nonalcoholic fatty liver (NAFL) is receiving increasing attention. Mice fed a
Externí odkaz:
https://doaj.org/article/89c90e55dae94963bbdefe45f6187e67
Autor:
Mahmoud Ahmed, Omar Elashkar, Jong Youl Lee, Eun Ae Jeong, Kyung Eun Kim, Gu Seob Roh, Deok Ryong Kim
Publikováno v:
All Life, Vol 15, Iss 1, Pp 555-561 (2022)
Ob/ob mice are leptin-deficient animals with uninhibited food intake and susceptibility to gain weight and develop type 2 diabetes. The mice have been used to study obesity and diabetes. We generated a dataset of different tissue gene expressions fro
Externí odkaz:
https://doaj.org/article/43d0f2bf0774430480b89904a1a6ad3f
Akademický článek
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Autor:
Bo Ra Moon, Ji Sook Han
Publikováno v:
Journal of Functional Foods, Vol 104, Iss , Pp 105538- (2023)
This study investigated whether HM-chromanone, a bioactive compound isolated from Portulaca oleracea L., inhibits lipid accumulation in adipose tissue and liver of C57BL/6J ob/ob mice. C57BL/6J mice were used for the normal group and C57BL/6J ob/ob m
Externí odkaz:
https://doaj.org/article/881507d32fe34343ad377fdb312c45b7
Autor:
Sashuang Dong, Chengwei Wu, Wencan He, Ruimin Zhong, Jing Deng, Ye Tao, Furong Zha, Zhenlin Liao, Xiang Fang, Hong Wei
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Obesity and atherosclerosis are the most prevalent metabolic diseases. ApoE−/− and ob/ob mice are widely used as models to study the pathogenesis of these diseases. However, how gut microbes, gut bacteriophages, and metabolites change in these tw
Externí odkaz:
https://doaj.org/article/2560eac478454f1e804f2a501451c327
Autor:
Yi Ding, Mariëlle C. Haks, Gabriel Forn-Cuní, Junling He, Natalia Nowik, Amy C. Harms, Thomas Hankemeier, Muhamed N. H. Eeza, Jörg Matysik, A. Alia, Herman P. Spaink
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Background Leptin plays a critical role in the regulation of metabolic homeostasis. However, the molecular mechanism and cross talks between leptin and metabolic pathways leading to metabolic homeostasis across different species are not clea
Externí odkaz:
https://doaj.org/article/b70f9089dc004eb8b507f251af7e5ba1
Autor:
Hana Lee, Jin-Ho Lee, Doyong Kim, Donghyun Hwang, Minjoo Lee, Halim Chung, Tack-Joong Kim, Han Sung Kim
Publikováno v:
Life, Vol 13, Iss 2, p 404 (2023)
Obesity is a disease in which fat is abnormally or excessively accumulated in the body, and many studies have been conducted to overcome it with various techniques. In this study, we evaluated whether micro-current stimulation (MCS) can be applied to
Externí odkaz:
https://doaj.org/article/d8f9889c2b7445aba9200ff8d3136b45
Autor:
Alireza Kashani, Asker Daniel Brejnrod, Chunyu Jin, Timo Kern, Andreas Nygaard Madsen, Louise Aas Holm, Georg K. Gerber, Jens-Christian Holm, Torben Hansen, Birgitte Holst, Manimozhiyan Arumugam
Publikováno v:
Animal Microbiome, Vol 1, Iss 1, Pp 1-16 (2019)
Abstract Background Growing evidence supports the role of gut microbiota in obesity and its related disorders including type 2 diabetes. Ob/ob mice, which are hyperphagic due to leptin deficiency, are commonly used models of obesity and were instrume
Externí odkaz:
https://doaj.org/article/0385eceaef9b422d9130571692ef5b3d
Autor:
Sandra M. Ferreira, José M. Costa-Júnior, Mirian A. Kurauti, Nayara C. Leite, Fernanda Ortis, Luiz F. Rezende, Helena C. Barbosa, Antonio C. Boschero, Gustavo J. Santos
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
ARHGAP21 is a RhoGAP protein implicated in the modulation of insulin secretion and energy metabolism. ARHGAP21 transient-inhibition increase glucose-stimulated insulin secretion (GSIS) in neonatal islets; however, ARHGAP21 heterozygote mice have a re
Externí odkaz:
https://doaj.org/article/fdc07da93c1544ea8351cc27ecaffc88