Zobrazeno 1 - 10
of 3 238
pro vyhledávání: '"ob/ob"'
Autor:
Yiming Ding, Xulei Dai, Miaoye Bao, Yuanming Xing, Junhui Liu, Sihai Zhao, Enqi Liu, Zuyi Yuan, Liang Bai
Publikováno v:
Animal Models and Experimental Medicine, Vol 6, Iss 4, Pp 317-328 (2023)
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is the main reason for cirrhosis and hepatocellular carcinoma. As a starting point for NAFLD, the treatment of nonalcoholic fatty liver (NAFL) is receiving increasing attention. Mice fed a
Externí odkaz:
https://doaj.org/article/89c90e55dae94963bbdefe45f6187e67
Autor:
Mahmoud Ahmed, Omar Elashkar, Jong Youl Lee, Eun Ae Jeong, Kyung Eun Kim, Gu Seob Roh, Deok Ryong Kim
Publikováno v:
All Life, Vol 15, Iss 1, Pp 555-561 (2022)
Ob/ob mice are leptin-deficient animals with uninhibited food intake and susceptibility to gain weight and develop type 2 diabetes. The mice have been used to study obesity and diabetes. We generated a dataset of different tissue gene expressions fro
Externí odkaz:
https://doaj.org/article/43d0f2bf0774430480b89904a1a6ad3f
Autor:
Gang Yu, Feng Cao, Tingting Hou, Yunsheng Cheng, Benli Jia, Liang Yu, Wanjing Chen, Yanyan Xu, Mingming Chen, Yong Wang
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-18 (2022)
Abstract Background Little is known about how the obesogenic environment influences emotional states associated with glial responses and neuronal function. Here, we investigated glial reactivation and neuronal electrophysiological properties in emoti
Externí odkaz:
https://doaj.org/article/3cfc5ad6e8764b17a1968cffb48ae53f
Autor:
Bo Ra Moon, Ji Sook Han
Publikováno v:
Journal of Functional Foods, Vol 104, Iss , Pp 105538- (2023)
This study investigated whether HM-chromanone, a bioactive compound isolated from Portulaca oleracea L., inhibits lipid accumulation in adipose tissue and liver of C57BL/6J ob/ob mice. C57BL/6J mice were used for the normal group and C57BL/6J ob/ob m
Externí odkaz:
https://doaj.org/article/881507d32fe34343ad377fdb312c45b7
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity, Vol Volume 14, Pp 4875-4887 (2021)
Allen D Smith,1 Anya Fan,2 Bolin Qin,1 Neemesh Desai,2 Aiping Zhao,2 Terez Shea-Donohue3 1Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, U.S. Department of Agriculture, Beltsville
Externí odkaz:
https://doaj.org/article/c8913c3d5a874daea6f1a022c3d2cb09
Akademický článek
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Autor:
Sashuang Dong, Chengwei Wu, Wencan He, Ruimin Zhong, Jing Deng, Ye Tao, Furong Zha, Zhenlin Liao, Xiang Fang, Hong Wei
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Obesity and atherosclerosis are the most prevalent metabolic diseases. ApoE−/− and ob/ob mice are widely used as models to study the pathogenesis of these diseases. However, how gut microbes, gut bacteriophages, and metabolites change in these tw
Externí odkaz:
https://doaj.org/article/2560eac478454f1e804f2a501451c327
Autor:
Yi Ding, Mariëlle C. Haks, Gabriel Forn-Cuní, Junling He, Natalia Nowik, Amy C. Harms, Thomas Hankemeier, Muhamed N. H. Eeza, Jörg Matysik, A. Alia, Herman P. Spaink
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Background Leptin plays a critical role in the regulation of metabolic homeostasis. However, the molecular mechanism and cross talks between leptin and metabolic pathways leading to metabolic homeostasis across different species are not clea
Externí odkaz:
https://doaj.org/article/b70f9089dc004eb8b507f251af7e5ba1
Autor:
Francesco Suriano, Sara Vieira-Silva, Gwen Falony, Martin Roumain, Adrien Paquot, Rudy Pelicaen, Marion Régnier, Nathalie M. Delzenne, Jeroen Raes, Giulio G. Muccioli, Matthias Van Hul, Patrice D. Cani
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-20 (2021)
Abstract Background Leptin-deficient ob/ob mice and leptin receptor-deficient db/db mice are commonly used mice models mimicking the conditions of obesity and type 2 diabetes development. However, although ob/ob and db/db mice are similarly gaining w
Externí odkaz:
https://doaj.org/article/d890b4d856184f9f98fdd2efbb56f9bd
Publikováno v:
Nutrients, Vol 15, Iss 9, p 2023 (2023)
Type 2 diabetes is a disease characterized by hyperglycemia and is a growing health problem worldwide. Since many known diabetes drugs are side effects, it is necessary to develop natural substances with guaranteed safety. HM-chromanone isolated from
Externí odkaz:
https://doaj.org/article/a53e10c9749a464884cfe21b2be1616e