Zobrazeno 1 - 10
of 43
pro vyhledávání: '"nutrient-sensing pathway"'
Autor:
Yu-Peng Han, Li-Juan Liu, Jia-Lin Yan, Meng-Yuan Chen, Xiang-Fei Meng, Xin-Ru Zhou, Ling-Bo Qian
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Diabetic nephropathy (DN), the leading cause of end-stage renal disease, is the most significant microvascular complication of diabetes and poses a severe public health concern due to a lack of effective clinical treatments. Autophagy is a lysosomal
Externí odkaz:
https://doaj.org/article/ae9e12f31fc74c93aae0f6a1b5070a0b
Autor:
Li Yin, Alexander Christopher Gregg, Alessandra Marie Riccio, Nicholas Hoyt, Zain Hussain Islam, Jungeun Ahn, Quang Le, Paranjay Patel, Mengxue Zhang, Xinran He, Matthew McKinney, Eric Kent, Bowen Wang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Abdominal aortic aneurysm (AAA) is a prevalent vascular disease with high mortality rates upon rupture. Despite its prevalence in elderly populations, there remain limited treatment options; invasive surgical repair, while risky, is the only therapeu
Externí odkaz:
https://doaj.org/article/e9f19b18307040a09cd4eb6535e04965
Autor:
Ye Chen, Sherif Hamidu, Xintong Yang, Yiqi Yan, Qilong Wang, Lin Li, Patrick Kwabena Oduro, Yuhong Li
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Accelerated biological aging, which involves the gradual decline of organ or tissue functions and the distortion of physiological processes, underlies several human diseases. Away from the earlier free radical concept, telomere attrition, cellular se
Externí odkaz:
https://doaj.org/article/e146802fa143457dab0edf80b2bc9ef0
Publikováno v:
Frontiers in Marine Science, Vol 7 (2020)
The study was conducted to explore the improvement function of marine protein hydrolyzates on nutritive values of diets for largemouth bass. The diet with no inclusion of marine protein hydrolyzate was considered as the control (NC), and four other d
Externí odkaz:
https://doaj.org/article/034cef3bee3342ba8458b0669900f2d1
Akademický článek
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Akademický článek
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Autor:
Rosalba La Grotta, Chiara Frigé, Giulia Matacchione, Fabiola Olivieri, Paola de Candia, Antonio Ceriello, Francesco Prattichizzo
Publikováno v:
International Journal of Molecular Sciences. 23:12325
Caloric restriction promotes longevity in multiple animal models. Compounds modulating nutrient-sensing pathways have been suggested to reproduce part of the beneficial effect of caloric restriction on aging. However, none of the commonly studied cal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7b5463605177a87c483d9ee692b656
https://doi.org/10.3390/ijms232012325
https://doi.org/10.3390/ijms232012325
Publikováno v:
Geriatrics, Vol 5, Iss 95, p 95 (2020)
Geriatrics
Geriatrics
Both life span and health span are influenced by genetic, environmental and lifestyle factors. With the genetic influence on human life span estimated to be about 20–25%, epigenetic changes play an important role in modulating individual health sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cdc06be9d973aa2e7715af5002a01a8
https://www.mdpi.com/2308-3417/5/4/95
https://www.mdpi.com/2308-3417/5/4/95
Akademický článek
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Autor:
Giulia Accardi, Anna Aiello, Claudia Virruso, Giuseppina Candore, Giusi Taormina, Calogero Caruso, Caterina Maria Gambino, Mario G. Mirisola
Publikováno v:
Expert Opinion on Therapeutic Targets. 21:371-380
Introduction: In the present paper, the authors have discussed anti-aging strategies which aim to slow the aging process and to delay the onset of age-related diseases, focusing on nutrient sensing pathways (NSPs) as therapeutic targets. Indeed, seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6fc046d1ef2b96fbd69b60328df9d4
https://doi.org/10.1080/14728222.2017.1294684
https://doi.org/10.1080/14728222.2017.1294684