Reduction of myeloid‐derived suppressor cells in prostate cancer murine models and patients following white button mushroom treatment

Autor: Xiaoqiang Wang, Shoubao Ma, Przemyslaw Twardowski, Clayton Lau, Yin S. Chan, Kelly Wong, Sai Xiao, Jinhui Wang, Xiwei Wu, Paul Frankel, Timothy G. Wilson, Timothy W Synold, Cary Presant, Tanya Dorff, Jianhua Yu, David Sadava, Shiuan Chen

Publikováno v: Clinical and Translational Medicine, Vol 14, Iss 10, Pp n/a-n/a (2024)

Abstract Background In a previously reported Phase I trial, we observed therapy‐associated declines in circulating myeloid‐derived suppressor cells (MDSCs) with the administration of white button mushroom (WBM) tablets in prostate cancer (PCa) pa

Externí odkaz: https://doaj.org/article/77ac3f0171a649cc910c82256ea2576a

Novel inhibitory effect of Omega-3 fatty acids regulating pancreatic cancer progression.

Autor: Garay MI; Instituto de Investigaciones en Ciencias de la Salud, INICSA (CONICET - FCM UNC), 5016 Córdoba, Argentina.; Instituto de Biología Celular y Cátedra de Biología Celular, Histología y Embriología, FCM-UNC, 5016 Córdoba, Argentina., Mazo T; Instituto de Investigaciones en Ciencias de la Salud, INICSA (CONICET - FCM UNC), 5016 Córdoba, Argentina.; Instituto de Biología Celular y Cátedra de Biología Celular, Histología y Embriología, FCM-UNC, 5016 Córdoba, Argentina., Ferrero V; Instituto de Investigaciones en Ciencias de la Salud, INICSA (CONICET - FCM UNC), 5016 Córdoba, Argentina.; Instituto de Biología Celular y Cátedra de Biología Celular, Histología y Embriología, FCM-UNC, 5016 Córdoba, Argentina., Barotto NN; Instituto de Biología Celular y Cátedra de Biología Celular, Histología y Embriología, FCM-UNC, 5016 Córdoba, Argentina., Lagares C; Instituto de Investigaciones en Ciencias de la Salud, INICSA (CONICET - FCM UNC), 5016 Córdoba, Argentina., Granton MF; Instituto de Biología Celular y Cátedra de Biología Celular, Histología y Embriología, FCM-UNC, 5016 Córdoba, Argentina., Moreira-Espinoza MJ; Instituto de Biología Celular y Cátedra de Biología Celular, Histología y Embriología, FCM-UNC, 5016 Córdoba, Argentina., Cremonezzi DC; Departamento de Patología, Hospital Nacional de Clínicas, FCM-UNC, 5000 Córdoba, Argentina., Comba A; Department of Pathology, Division Neuropathology, Heersink School of Medicine, University of Alabama at Birmingham, AL, 35294, USA., Brunotto MN; Instituto de Investigaciones en Ciencias de la Salud, INICSA (CONICET - FCM UNC), 5016 Córdoba, Argentina.; Departamento de Biología Bucal, Facultad de Odontología, UNC, 5016 Córdoba, Argentina., Tolosa EJ; Schulze Center for Novel Therapeutics, Mayo Clinic, Rochester, MN 55905, USA., Fernandez-Zapico ME; Schulze Center for Novel Therapeutics, Mayo Clinic, Rochester, MN 55905, USA., Pasqualini ME; Instituto de Investigaciones en Ciencias de la Salud, INICSA (CONICET - FCM UNC), 5016 Córdoba, Argentina.; Instituto de Biología Celular y Cátedra de Biología Celular, Histología y Embriología, FCM-UNC, 5016 Córdoba, Argentina.

Publikováno v: Carcinogenesis [Carcinogenesis] 2025 Jan 01. Date of Electronic Publication: 2025 Jan 01.

Reduction of myeloid-derived suppressor cells in prostate cancer murine models and patients following white button mushroom treatment.

Autor: Wang X; Department of Cancer Biology & Molecular Medicine, Beckman Research Institute, City of Hope, Duarte, California, USA., Ma S; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Comprehensive Cancer Center, Duarte, California, USA., Twardowski P; Department of Urology and Urologic Oncology, Providence Saint John's Cancer Institute, Santa Monica, California, USA., Lau C; Department of Surgery, City of Hope Comprehensive Cancer Center, Duarte, California, USA., Chan YS; Department of Cancer Biology & Molecular Medicine, Beckman Research Institute, City of Hope, Duarte, California, USA., Wong K; Department of Cancer Biology & Molecular Medicine, Beckman Research Institute, City of Hope, Duarte, California, USA., Xiao S; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Comprehensive Cancer Center, Duarte, California, USA., Wang J; Integrative Genomics Core, Beckman Research Institute, City of Hope, Monrovia, California, USA., Wu X; Department of Computational and Quantitative Medicine, Beckman Research Institute, City of Hope, Duarte, California, USA., Frankel P; Department of Computational and Quantitative Medicine, Beckman Research Institute, City of Hope, Duarte, California, USA., Wilson TG; Department of Urology and Urologic Oncology, Providence Saint John's Cancer Institute, Santa Monica, California, USA., Synold TW; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA., Presant C; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA., Dorff T; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA., Yu J; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Comprehensive Cancer Center, Duarte, California, USA., Sadava D; Department of Cancer Biology & Molecular Medicine, Beckman Research Institute, City of Hope, Duarte, California, USA., Chen S; Department of Cancer Biology & Molecular Medicine, Beckman Research Institute, City of Hope, Duarte, California, USA.

Publikováno v: Clinical and translational medicine [Clin Transl Med] 2024 Oct; Vol. 14 (10), pp. e70048.