Zobrazeno 1 - 10
of 942
pro vyhledávání: '"nucleotide variation"'
Autor:
Elvis Quansah, Ji Zhao, Kenneth Kofi Eduful, Enock Kofi Amoako, Lucas Amenga-Etego, Faustina Halm-Lai, Qingli Luo, Jilong Shen, Chao Zhang, Li Yu
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-11 (2024)
Abstract Background PfAP2-EXP2 is located within chromosome 6 of Plasmodium falciparum recently identified to be undergoing an extensive selective sweep in West African isolates. The gene encoding this transcription factor, PfAP2-EXP2, is essential a
Externí odkaz:
https://doaj.org/article/5c67f25ae32446e29ba28d89cc7ae37f
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract The therapeutic efficacy of lung adenocarcinoma (LUAD), the most prevalent histological subtype of primary lung cancer, remains inadequate, with accurate prognostic assessment posing significant challenges. This study sought to elucidate the
Externí odkaz:
https://doaj.org/article/85325ced39614cf1a2b1653fad2ffaed
Autor:
Menglu Hu, Wentao Yang, Ruiyi Yan, Jiayu Chi, Qi Xia, Yilin Yang, Yinhan Wang, Lejia Sun, Ping Li
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Exploration of adaptive evolutionary changes at the genetic level in vaginal microbial communities during different stages of cervical cancer remains limited. This study aimed to elucidate the mutational profile of the vaginal mic
Externí odkaz:
https://doaj.org/article/e797c26e127c449389b117931e64f075
Autor:
Kunna Zhang, Menglu Hu, Wentao Yang, Zhexia Hu, Yun Rong, Biyun Luo, Mengjia Wang, Yajuan Cheng, Rui Zhang, Ning Lv, Qian Zhou, Xueling Zhang
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37986- (2024)
Background: The composition of the gut microbiome has been recorted to be strongly associated with gestational diabetes mellitus (GDM), but mutational characterization of the microbiome in patients with GDM has been overlooked. Here, we revealed the
Externí odkaz:
https://doaj.org/article/73ff8df579f04dab91f0929445351464
Publikováno v:
International Journal of General Medicine, Vol Volume 16, Pp 4617-4628 (2023)
Xi-Qin Wang,1 Fang Yuan,2 Bao-Rui Yu2 1Department of Internal Medicine, Yuhua Yunfang Integrated Traditional Chinese and Western Medicine Clinic, Shijiazhuang, Hebei, 050023, People’s Republic of China; 2Department of Cardiovascular Medicine, Fuwai
Externí odkaz:
https://doaj.org/article/013d1f44d4cb468dac6fa70203091729
Autor:
Mehryar Zargari, Negar Maadi, Maysam Rezapour, Abouzar Bagheri, Samane Fallahpour, Mani Nosrati, Abdolkarim Mahrooz
Publikováno v:
Advanced Biomedical Research, Vol 13, Iss 1, Pp 38-38 (2024)
Background: This study aimed to assess the serum activity of paraoxonase 1 (PON1) in patients with coronary artery disease (CAD) based on two genetic variants including the -108C/T variant in the promoter region and the rs3735590 variant in the bindi
Externí odkaz:
https://doaj.org/article/3052253d593842eb9a83c6c5fa5941de
Autor:
Szilvia Jakab, Ádám Bálint, Karolina Cseri, Krisztina Bali, Eszter Kaszab, Marianna Domán, Máté Halas, Krisztina Szarka, Krisztián Bányai
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2024)
A tiling amplicon sequencing protocol was developed to analyse the genome sequence stability of the modified live PRRSV vaccine strain, Porcilis MLV. The backbone of the ARTIC-style protocol was formed by 34 individual primer pairs, which were divide
Externí odkaz:
https://doaj.org/article/c52b9791a9e14f0590f1de71f7c9489a
Publikováno v:
mSystems, Vol 8, Iss 6 (2023)
ABSTRACT Adaptive evolutionary changes can precede the ecological changes in the gut microbial communities under constant host selection pressure, yet their association with host diseased status was underexplored. Explore shared disease-associated si
Externí odkaz:
https://doaj.org/article/ce78c07ab98f4027a8cf3b0eebde5ee7
Autor:
Mariam M. Al Eissa, Raniah S. Alotibi, Bader Alhaddad, Taghrid Aloraini, Manar S. Samman, Abdulrahman AlAsiri, Mohamed Abouelhoda, Amerh S. AlQahtani
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Physicians face diagnostic dilemmas upon reports indicating disease variants of unknown significance (VUS). The most puzzling cases are patients with rare diseases, where finding another matched genotype and phenotype to associate their
Externí odkaz:
https://doaj.org/article/95ac75cb26ba4c4f8cf5594da067c504
Autor:
Yaqing He, Shengyuan Dang, Wentai Ma, Long Chen, Renli Zhang, Shujiang Mei, Xinyi Wei, Qiuying Lv, Bo Peng, Ying Sun, Dongfeng Kong, Jiancheng Chen, Shimin Li, Xiujuan Tang, Qingju Lu, Can Zhu, Zhigao Chen, Jia Wan, Xuan Zou, Mingkun Li, Tiejiang Feng, Lili Ren, Jianwei Wang
Publikováno v:
Biosafety and Health, Vol 5, Iss 1, Pp 62-67 (2023)
We analyzed variations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome during a flight-related cluster outbreak of coronavirus disease 2019 (COVID-19) in Shenzhen, China, to explore the characteristics of SARS-CoV-2 transmi
Externí odkaz:
https://doaj.org/article/ade61fc07e564e29b7a73346ff04ec2a