Zobrazeno 1 - 10
of 739
pro vyhledávání: '"nuclear factor kappa B (NF-κB)"'
Autor:
Adeyemi Fatai Odetayo, Roland Eghoghosoa Akhigbe, Moses Agbomhere Hamed, Morufu Eyitayo Balogun, David Tolulope Oluwole, Luqman Aribidesi Olayaki
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundTamoxifen (TAM) is a widely used drug in patients with gynecomastia and breast cancer. TAM exerts its anticancer effects via its antiestrogenic activities. Unfortunately, TAM has been reported to exert gonadotoxic effects on male testes. Th
Externí odkaz:
https://doaj.org/article/5e2fb2eec81a42fea9d8b0e500282f66
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Coxsackievirus Group B type 5 (CVB5), an important pathogen of hand-foot-mouth disease, is also associated with neurological complications and poses a public health threat to young infants. Among the CVB5 proteins, the nonstructural protein
Externí odkaz:
https://doaj.org/article/37759384c6634e8f89762631bd0b61a9
Autor:
SKV Manjari, Sharon Mariam Abraham, R. Poornima, Rajneesh Kumar Chaturvedi, Shuvadeep Maity, Pragya Komal
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp 116-125 (2023)
Introduction: 3-NP induction in rodent models has been shown to induce selective neurodegeneration in the striatum followed by the cortex (Brouillet, 2014). However, it remains unclear whether, under such a neurotoxic condition, characterized by neur
Externí odkaz:
https://doaj.org/article/d60081bd93a944d797eb0d05099382cc
Publikováno v:
Pharmaceutical Biology, Vol 61, Iss 1, Pp 1082-1093 (2023)
AbstractContext Aryl hydrocarbon receptor (AhR) agonists are potential therapeutic agents for ulcerative colitis (UC). Indirubin (IDR), which is a natural AhR ligand approved for leukemia treatment, ameliorates dextran sulfate sodium (DSS)-induced co
Externí odkaz:
https://doaj.org/article/7959cf9810e34004b272385162b47c29
Autor:
Jun Xu, Kaifeng Zhou, Huijie Gu, Yiming Zhang, Liang Wu, Chong Bian, Zhongyue Huang, Guangnan Chen, Xiangyang Cheng, Xiaofan Yin
Publikováno v:
Biomolecules & Biomedicine (2023)
This study aimed to elucidate the roles of microRNA (miR)-4738-3p and the collagen type I alpha 2 chain (COL1A2) gene in the pathogenesis of osteoarthritis (OA) through bioinformatics analysis and cellular assays. The GSE55235 dataset was analyzed us
Externí odkaz:
https://doaj.org/article/87ec81c157284939990cc69a9bddd9dc
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 1090-1100 (2023)
Nod-like receptor family pyrin domain-containing protein 12 (NLRP12) is one of the critical pattern recognition receptors which participates in the regulation of multiple inflammatory responses. Mutations in NLRP12 cause exceptionally rare NLRP12-ass
Externí odkaz:
https://doaj.org/article/e807c748f74b4bcc81b7d06afa033122
Autor:
Ade Rifka Junita, Firdaus Hamid, Budu Budu, Rosdiana Natzir, Yusmina Hala, Gemini Alam, Rosana Agus, Burhanuddin Bahar, Ahmad Syukri, Muhammad Reza Primaguna, Ressy Dwiyanti, Andini Febrianti, Muhammad Sabir, Azhar Azhar, Mochammad Hatta
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e22327- (2023)
Purpose: To prove the effect of Miana (M), Quercetin (Q), and the combination as an anti-inflammatory agent and Cefixime (C) as an antibiotic in Balb/c mice infected with Salmonella enterica serovar Typhi (S. Typhi) and related to the dynamics of NF-
Externí odkaz:
https://doaj.org/article/423df8f7f2304e19a45655779b082d28
Publikováno v:
Journal of Inflammation, Vol 19, Iss 1, Pp 1-11 (2022)
Abstract Background Chronic inflammation and oxidant/antioxidant imbalance are two main pathological features associated with lipopolysaccharide (LPS)-induced acute lung injury (ALI). The following study investigated the protective role of hydrogen (
Externí odkaz:
https://doaj.org/article/700637d736914aa89925564554e2af18
Autor:
Shao-Chun Wu, Cheng-Shyuan Rau, Yi-Chan Wu, Chia-Jung Wu, Chia-Wen Tsai, Lien-Hung Huang, Chia-Wei Lin, Tsu-Hsiang Lu, Ming-Yu Yang, Ching-Hua Hsieh
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 534 (2024)
Circulating exosomes derived from polymicrobial sepsis contain various non-coding RNAs and proteins. Isobaric tags for a relative or absolute quantitation proteomic analysis of the exosomal content revealed 70 dysregulated proteins in the circulating
Externí odkaz:
https://doaj.org/article/fe0fb799a3854657922ad036c2840436
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