Zobrazeno 1 - 10
of 568
pro vyhledávání: '"nsP3"'
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Over the course of the COVID-19 pandemic, several SARS-CoV-2 variants have emerged that may exhibit different etiological effects such as enhanced transmissibility and infectivity. However, genetic variations that reduce virulence and deteri
Externí odkaz:
https://doaj.org/article/cbbb80dbd22b4143861a3b5ea6e51099
Autor:
Yue Ma-Lauer, Pengyuan Li, Daniela Niemeyer, Anja Richter, Konstantin Pusl, Brigitte von Brunn, Yi Ru, Chengyu Xiang, Sebastian Schwinghammer, Jia Liu, Priya Baral, Emilia J. Berthold, Haibo Qiu, Avishek Roy, Elisabeth Kremmer, Heinrich Flaswinkel, Christian Drosten, Zhendong Jin, Albrecht von Brunn
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionOxysterol-binding protein (OSBP) is known for its crucial role in lipid transport, facilitating cholesterol exchange between the Golgi apparatus and endoplasmic reticulum membranes. Despite its established function in cellular processes,
Externí odkaz:
https://doaj.org/article/93b9e17369b8497681de160989f96dc7
Autor:
Kirti Sharma, Manjinder Singh, Pratibha Sharma, Sumesh C. Sharma, Somdutt Mujwar, Mohit Kapoor, Krishna Kumar Mishra, Tanveer A. Wani
Publikováno v:
Molecules, Vol 29, Iss 6, p 1406 (2024)
SARS-CoV, an RNA virus, is contagious and displays a remarkable degree of adaptability, resulting in intricate disease presentations marked by frequent genetic mutations that can ultimately give rise to drug resistance. Targeting its viral replicatio
Externí odkaz:
https://doaj.org/article/2a42876fa0324a53a90033f23b733da0
Publikováno v:
Viruses, Vol 16, Iss 3, p 424 (2024)
Porcine epidemic diarrhea virus (PEDV) is a highly pathogenic swine coronavirus that causes diarrhea and high mortality in piglets, resulting in significant economic losses within the global swine industry. Nonstructural protein 3 (Nsp3) is the large
Externí odkaz:
https://doaj.org/article/31c9c334103248539021e892d5cfe24d
Akademický článek
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Akademický článek
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Akademický článek
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Publikováno v:
Majalah Obat Tradisional, Vol 27, Iss 1, Pp 24-31 (2022)
Green tea catechin compounds (Camellia sinensis L. Kuntze) have an antiviral activity such as influenza, hepatitis B, hepatitis C, herpes simplex virus, HIV, and proven in vitro antiviral influenza against NSP5 in SARS CoV. These considerations are u
Externí odkaz:
https://doaj.org/article/2783d32651bd4a8c99fddee86fecba67
Autor:
Purwaniati Purwaniati, Asep Roni
Publikováno v:
Pharmaciana, Vol 12, Iss 1, Pp 1-12 (2022)
COVID-19 is still a global pandemic. The transmission is very fast and wide. Its prevalence continues to increase. There is no specific antiviral drug for SARS CoV 2 yet. This study aims to find lead compounds from compounds derived from spices that
Externí odkaz:
https://doaj.org/article/9380cd8be7e44afcb1705fb78194f378
Publikováno v:
Viruses, Vol 15, Iss 12, p 2291 (2023)
Since the emergence of SARS-CoV-2, many genetic variations within its genome have been identified, but only a few mutations have been found in nonstructural proteins (NSPs). Among this class of viral proteins, NSP3 is a multidomain protein with 16 di
Externí odkaz:
https://doaj.org/article/de545eac3aa245edabc1e70da20f2fce