Zobrazeno 1 - 10
of 568
pro vyhledávání: '"ns5a inhibitor"'
Autor:
Jeong Heo, Yoon Jun Kim, Sung Wook Lee, Youn-Jae Lee, Ki Tae Yoon, Kwan Soo Byun, Yong Jin Jung, Won Young Tak, Sook-Hyang Jeong, Kyung Min Kwon, Vithika Suri, Peiwen Wu, Byoung Kuk Jang, Byung Seok Lee, Ju-Yeon Cho, Jeong Won Jang, Soo Hyun Yang, Seung Woon Paik, Hyung Joon Kim, Jung Hyun Kwon, Neung Hwa Park, Ju Hyun Kim, In Hee Kim, Sang Hoon Ahn, Young-Suk Lim
Publikováno v:
The Korean Journal of Internal Medicine, Vol 38, Iss 4, Pp 504-513 (2023)
Background/Aims Despite the availability of direct-acting antivirals (DAAs) for chronic hepatitis C virus (HCV) infection in Korea, need remains for pangenotypic regimens that can be used in the presence of hepatic impairment, comorbidities, or prior
Externí odkaz:
https://doaj.org/article/95d31ece645e44a2ae4df56674553d45
Publikováno v:
International Journal of Women's Health, Vol Volume 11, Pp 617-628 (2019)
Christophe Hézode,1 Paul Kwo,2 Jan Sperl,3 Peggy Hwang,4 Jianmin Long,4 Rohit Talwani,4 Michael N Robertson,4 Barbara A Haber4 1Service d’Hépatologie, Hôpital Henri-Mondor, AP-HP, Université Paris-Est, INSERM U955, Créteil, France; 2Division o
Externí odkaz:
https://doaj.org/article/a103fe64d4d94f06831c85193678a9a9
Autor:
Eric M. Yoshida, Paul Kwo, Kosh Agarwal, Christophe Duvoux, François Durand, Markus Peck-Radosavljevic, Leslie Lilly, Bernard Willems, Hugo Vargas, Princy Kumar, Robert S. Brown Jr., Yves Horsmans, Shampa De-Oertel, Sarah Arterburn, Hadas Dvory-Sobol, Diana M. Brainard, John G. McHutchison, Norah Terrault, Mario Rizzetto, Beat Müllhaupt
Publikováno v:
Annals of Hepatology, Vol 16, Iss 3, Pp 375-381 (2017)
Introduction: Recurrence of HCV infection in patients with chronic hepatitis C virus (HCV) at the time of liver transplantation is nearly universal and reduces the likelihood of graft and patient survival. Materials and methods: We evaluated outcomes
Externí odkaz:
https://doaj.org/article/7b99e5b0953345a782fe2e657a4e893c
Autor:
Westerhout KY, Bouwmeester W, Duchesne I, Pisini M, Piena MA, Damele F, Gueron B, Treur M, Belsey J
Publikováno v:
ClinicoEconomics and Outcomes Research, Vol Volume 9, Pp 163-172 (2017)
Kirsten Y Westerhout,1 Walter Bouwmeester,1 Inge Duchesne,2 Marta Pisini,2 Marjanne A Piena,1 Francesco Damele,3 Beatrice Gueron,2 Maarten Treur,1 Jonathan Belsey4 1Pharmerit BV, Marten Meesweg, Rotterdam, the Netherlands; 2Janssen EMEA, Turnhoutsewe
Externí odkaz:
https://doaj.org/article/70954e8a69ac45de8250beaa1b1a7449
Autor:
Maribel Rodriguez-Torres, Eric Läwitz, Bienvenido Yangco, Lennox Jeffers, Steven-Huy Han, Paul J. Thuluvath, Vinod Rustgi, Stephen Harrison, Reem Ghalib, John M. Vierling, Velimir Luketic, Philippe J. Zamor, Natarajan Ravendhran, Timothy R. Morgan, Brian Pearlman, Christopher O’Brien, Hicham Khallafi, Nikolaos Pyrsopoulos, George Kong, Fiona McPhee, Philip D. Yin, Eric Hughes, Michelle Treitel
Publikováno v:
Annals of Hepatology, Vol 15, Iss 6, Pp 834-845 (2016)
Background. Patient race and ethnicity have historically impacted HCV treatment response. This phase 3 study evaluated daclatasvir with peginterferon-alfa-2a/ribavirin (pegIFN alfa-2a/RBV) in treatment-naive black/African American (AA), Latino, and w
Externí odkaz:
https://doaj.org/article/758320977acf45fe990b1d476981cdbb
Akademický článek
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Autor:
Kazuaki Chayama, C. Nelson Hayes
Publikováno v:
Viruses, Vol 7, Iss 10, Pp 5328-5342 (2015)
Sustained virological response (SVR) rates have increased dramatically following the approval of direct acting antiviral (DAA) therapies. While individual DAAs have a low barrier to resistance, most patients can be successfully treated using DAA comb
Externí odkaz:
https://doaj.org/article/32155f913f29459da8b9033f2a64947d
Autor:
C. Nelson Hayes, Kazuaki Chayama
Publikováno v:
Journal of the Formosan Medical Association, Vol 114, Iss 3, Pp 204-215 (2015)
Advances in understanding the hepatitis C virus (HCV) life cycle and the urgent need to find complementary direct-acting antiviral (DAA) therapies has led to substantial advancements in treating chronic hepatitis C. The introduction of telaprevir and
Externí odkaz:
https://doaj.org/article/ff353260122049ce8942d1da435f6f0d
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Vishnu Murthy Marisetti, Pedavenkatagari Narayana Reddy, Vijaya Lakshmi Chapala, Giri Prasad Malavattu, Nagaraju Kerru, Naresh Kumar Katari
Publikováno v:
Russian Journal of General Chemistry. 91:932-938
Large-scale enantioselective synthesis of the chiral amine unit of HCV NS5A inhibitor Elbasvir has been accomplished in six steps, with 55% overall yield. The process includes a highly enantioselective reduction of the NH imine using R-(+)-diphenylpr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4165c60d6ba2387b0b733c675533336
https://doi.org/10.1134/s107036322105025x
https://doi.org/10.1134/s107036322105025x