Zobrazeno 1 - 10
of 26
pro vyhledávání: '"nrf2/nfe2l2"'
Akademický článek
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Autor:
Jonathan Poh, Amy H. Ponsford, James Boyd, Jonathan Woodsmith, Ulrich Stelzl, Erich Wanker, Nicholas Harper, David MacEwan, Christopher M. Sanderson
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101686- (2020)
NRF2 (NFE2L2) is a cytoprotective transcription factor associated with >60 human diseases, adverse drug reactions and therapeutic resistance. To provide insight into the complex regulation of NRF2 responses, 1962 predicted NRF2-partner interactions w
Externí odkaz:
https://doaj.org/article/7cf911239b8246beb0bcaf25f01086c0
Autor:
Xiaohua Song, Dingxin Long
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Ferroptosis is a kind of regulated cell death (RCD) caused by the redox state disorder of intracellular microenvironment controlled by glutathione (GSH) peroxidase 4 (GPX4), which is inhibited by iron chelators and lipophilic antioxidants. In additio
Externí odkaz:
https://doaj.org/article/00e5a452642041b297b73b5b405e63af
Autor:
Kautilya Kumar Jena, Subhash Mehto, Srinivasa Prasad Kolapalli, Parej Nath, Swati Chauhan, Santosh Chauhan
Publikováno v:
Cell Stress, Vol 2, Iss 12, Pp 365-367 (2018)
The cellular stresses, genetic mutations, and environmental factors can critically affect the protein quality control checkpoints resulting in protein misfolding. Molecular chaperones play a crucial role in maintaining the healthy proteome by refoldi
Externí odkaz:
https://doaj.org/article/196fb500c5504214aae3f0ddba0ba257
Autor:
Kautilya Kumar Jena, Srinivasa Prasad Kolapalli, Subhash Mehto, Swati Chauhan, Santosh Chauhan
Publikováno v:
Molecular & Cellular Oncology, Vol 5, Iss 6 (2018)
Protein misfolding and protein aggregation are linked to several diseases commonly called as proteinopathies, which include cancer. Understanding the mechanisms of proteostasis could provide newer strategies to combat proteinopathies. We have recentl
Externí odkaz:
https://doaj.org/article/c993dae400ff49a09f45c73e0d176a72
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Amy H. Ponsford, James Boyd, Ulrich Stelzl, David J. MacEwan, Nicholas Harper, Christopher M. Sanderson, Erich E. Wanker, Jonathan Woodsmith, Jonathan Poh
Publikováno v:
Redox Biology, Vol 37, Iss, Pp 101686-(2020)
Redox Biology
Redox Biology
NRF2 (NFE2L2) is a cytoprotective transcription factor associated with >60 human diseases, adverse drug reactions and therapeutic resistance. To provide insight into the complex regulation of NRF2 responses, 1962 predicted NRF2-partner interactions w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d4f3c95173eb6ff536888daef39209
http://www.sciencedirect.com/science/article/pii/S2213231720308910
http://www.sciencedirect.com/science/article/pii/S2213231720308910
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Santosh Chauhan, Srinivasa Prasad Kolapalli, Pradyumna Kumar Sahoo, Biswajit Das, Parej Nath, Shantibhusan Senapati, Gulam Hussain Syed, Swati Chauhan, Kautilya Kumar Jena, Sunil K. Raghav, Abdul Ahad, Subhash Mehto
Publikováno v:
Cell Stress
Sequestration of protein aggregates in inclusion bodies and their subsequent degradation prevents proteostasis imbalance, cytotoxicity, and proteinopathies. The underlying molecular mechanisms controlling the turnover of protein aggregates are mostly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79de1c0e082f56fd16a1eacc838ce53c
https://pubmed.ncbi.nlm.nih.gov/31225461
https://pubmed.ncbi.nlm.nih.gov/31225461
Autor:
Lenka, Roubalová, Albena T, Dinkova-Kostova, David, Biedermann, Vladimír, Křen, Jitka, Ulrichová, Jiří, Vrba
Publikováno v:
Fitoterapia
Silybum marianum (milk thistle) is a medicinal plant used for the treatment of various liver disorders. This study examined whether the main flavonolignans from S. marianum (i.e. silybin, silychristin, silydianin) and their 2,3-dehydro derivatives (i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99487d2bc78654f7342479f183a8f101
https://pubmed.ncbi.nlm.nih.gov/28450126
https://pubmed.ncbi.nlm.nih.gov/28450126