Zobrazeno 1 - 10
of 43 823
pro vyhledávání: '"nrf2"'
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-14 (2024)
Abstract Background Hyperoside (quercetin-3-O-β-D-galactopyranoside) is a flavonol glycoside compound derived from plants in the Hypericum and Crataegus genera that reportedly exhibits an array of anti-inflammatory, antioxidant, and antitumor proper
Externí odkaz:
https://doaj.org/article/df39435c74164c2a885fa70f6b8e7fe6
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-29 (2024)
Abstract Background The Blood-Brain Barrier (BBB) is a complex and dynamic interface that regulates the exchange of molecules and cells between the blood and the central nervous system. It undergoes structural and functional throughout oxidative stre
Externí odkaz:
https://doaj.org/article/f56f4cbe0fb04f5e9ec4df2761c6c6e9
Autor:
Ke Ma, Lili Miao, Bo Li, Wenfei Yu, Fengzhao Liu, Kun Liu, Yang Li, Chengcheng Huang, Zhenguo Yang
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-24 (2024)
Abstract Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovitis that can lead to joint deformities. To date, more than 18 million individuals worldwide have been diagnosed with RA, making it one of the most prevalent autoimmune
Externí odkaz:
https://doaj.org/article/9d4046c7c05047b5825bfa0f922f554e
Autor:
Han Wu, Jianping Wu, Jianzhuo Jiang, Zeyu Qian, Shuang Yang, Yanze Sun, Hongxia Cui, Shengwen Li, Peng Zhang, Zhiqiang Zhou
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-17 (2024)
Abstract Background Radiation-induced myelopathy (RM) is a significant complication of radiotherapy with its mechanisms still not fully understood and lacking effective treatments. Compound 7 (C7) is a newly identified, potent, and selective inhibito
Externí odkaz:
https://doaj.org/article/93ce33ce8d864761a6037e5ffed81efd
Autor:
Kamal Baral, Spandan Joshi, Adriana Lopez, Gavisha Mugon, Aroma Chanda, Arya A. Chandrasheker, Cameron Hinton, Kapil Thapa, Arissa Mercer, Leah Spade, Gang Liu, Bhupal Prasad Bhetwal, Jia Fang, Bilon Khambu
Publikováno v:
FEBS Open Bio, Vol 14, Iss 11, Pp 1851-1863 (2024)
Hepatic proteomes are intricately controlled through biosynthesis, extracellular secretion, and intrahepatic degradation. Autophagy governs lysosome‐mediated intrahepatic degradation and the hepatic proteome. When autophagy is impaired, it leads to
Externí odkaz:
https://doaj.org/article/22a957af6fd64d09bc842ccbc286b605
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 11, Pp 1006-1019 (2024)
Abstract Berberine (BBR), a widely recognized traditional Chinese medicine, has attracted considerable attention for its promising anti‐inflammatory effects. The activation of nuclear factor erythroid 2‐related factor 2 (Nrf2) effectively safegua
Externí odkaz:
https://doaj.org/article/aa2a48707a63408e8a120d07c93b46fb
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 11105-11128 (2024)
Kunzhao Huang,* Xiaoyuan Yi,* Huaying Xie, Jianzhang Luo, Qingyu Zeng, Feifei He, Liyan Wang Digestive Department, The Affiliated Hospital of Guilin Medical College, Guilin, 541001, People’s Republic of China*These authors contributed e
Externí odkaz:
https://doaj.org/article/6a02a9fa16604b45ba6c4b2e0e344679
Autor:
Sulong Wang, Xin Yang, Kai Liu, Debin Xiong, Ainizier Yalikun, Yimurang Hamiti, Aihemaitijiang Yusufu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background Muscle atrophy caused by denervation is common in neuromuscular diseases, leading to loss of muscle mass and function. However, a comprehensive understanding of the overall molecular network changes during muscle denervation atrop
Externí odkaz:
https://doaj.org/article/20b3e31df8fc40ab8137871cc5cecb78
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 4779-4797 (2024)
Dan Luo,1– 3,* Yonghui Hou,1– 3,* Jiheng Zhan,1,2,* Yu Hou,1– 3 Zenglu Wang,4 Xing Li,1,2 Lili Sui,5 Shudong Chen,1,2 Dingkun Lin1,2 1Research Laboratory of Spine Degenerative Disease, The Second Affiliated Hospital of Guangzhou University of C
Externí odkaz:
https://doaj.org/article/577e3d847c3d42e99c8d8b2edc69bb2e
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 7687-7704 (2024)
Jie Xu,1,2 Liujun Tao,1 Liangyan Jiang,1 Jie Lai,1 Juntao Hu,1 Zhanhong Tang1 1Department of Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, People’s Republic of China; 2Department of C
Externí odkaz:
https://doaj.org/article/6f4b0658bcc04e0aad77c4b85acbdc8c