Zobrazeno 1 - 10
of 794
pro vyhledávání: '"novel therapeutics"'
Publikováno v:
International Journal of Translational Medicine, Vol 4, Iss 3, Pp 402-418 (2024)
While existing local therapies partially restore vision loss from diabetic retinopathy (DR), there is currently no reliable treatment to prevent the onset or stop the progression of the disease. This review seeks to explore the inflammatory molecular
Externí odkaz:
https://doaj.org/article/bf156e7da43d476ca458edfa7b709761
Autor:
Muhammad Tukur Ibrahim, Saudatu Chinade Ja'afaru, Adamu Uzairu, Anshuman Chandra, Muhammed Sani Sallau, Nagendra Singh
Publikováno v:
Scientific African, Vol 25, Iss , Pp e02326- (2024)
Schistosomiasis, caused by flatworm parasites, is a widespread disease resulting in chronic illness and fatalities globally. Given the risk of drug resistance and limited treatment options, finding new therapeutic options are crucial for managing and
Externí odkaz:
https://doaj.org/article/5d9d37f7974a4c5a9a6db42cf3b2f255
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 16, Iss 6, Pp 1281-1286 (2024)
Colorectal cancer (CRC) is a pervasive malignancy that stands as a prominent contributor to global cancer-related mortality. Among the numerous causative factors, the overexpression of human epidermal growth factor receptor 2 (HER2) is notably linked
Externí odkaz:
https://doaj.org/article/b8b86afd302241239297a775257208de
Autor:
Ed J. Griffen, Pascale Boulet
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
The COVID-19 pandemic demonstrated that the current purely market-driven approaches to drug discovery and development alone are insufficient to drive equitable access to new therapies either in preparation for, or in response to, pandemics. A new glo
Externí odkaz:
https://doaj.org/article/511114760f834da49e77e660edca800f
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/0dcaea4931c34a2e89b4929edc542ef3
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-23 (2023)
Abstract Liquid–liquid phase separation (LLPS) is a novel principle for interpreting precise spatiotemporal coordination in living cells through biomolecular condensate (BMC) formation via dynamic aggregation. LLPS changes individual molecules into
Externí odkaz:
https://doaj.org/article/52be7b24b2744cbc95cbb98567436aca
Autor:
Manuela Oliveira, Wilson Antunes, Salete Mota, Áurea Madureira-Carvalho, Ricardo Jorge Dinis-Oliveira, Diana Dias da Silva
Publikováno v:
Microorganisms, Vol 12, Iss 9, p 1920 (2024)
Antimicrobial resistance (AMR), frequently considered a major global public health threat, requires a comprehensive understanding of its emergence, mechanisms, advances, and implications. AMR’s epidemiological landscape is characterized by its wide
Externí odkaz:
https://doaj.org/article/c811f6445d2e47af980d55fec9c353c5
Autor:
Kyaw Zwar Myint, Mireia Sueca-Comes, Pamela Collier, Brinda Balasubramanian, Simran Venkatraman, John Gordan, Abed M. Zaitoun, Abhik Mukherjee, Arvind Arora, Noppadol Larbcharoensub, Chinnawut Suriyonplengsaeng, Kanokpan Wongprasert, Tavan Janvilisri, Dhanny Gomez, Anna M. Grabowska, Rutaiwan Tohtong, David O. Bates, Kiren Yacqub-Usman
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionBile duct cancer (cholangiocarcinoma, CCA) has a poor prognosis for patients, and despite recent advances in targeted therapies for other cancer types, it is still treated with standard chemotherapy. Anaplastic lymphoma kinase (ALK) has b
Externí odkaz:
https://doaj.org/article/169ad49512ff4bd2ae8d553a1e4dd8f5
Autor:
Hope Onohuean, Fanny Eseohe Onohuean, Sharon Iyobor Igbinoba, Joseph Obiezu Chukwujekwu Ezeonwumelu, Peter Chinedu Agu, Josiah Eseoghene Ifie, Tusubira Deusdedit, Patrick Maduabuchi Aja
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Mondia whitei root is often used in Africa as a local therapeutic agent for libido enhancement. The fractions of the M. whitei leaves (MWL) lack chemical characterization of their bioactive components and possible molecular target
Externí odkaz:
https://doaj.org/article/5dd1e490c21e4a9085abc7c4985cc3d0