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Akademický článek

Combined use of statins and inhibitors of arginase l-norvaline for correcting endotoksin-inducing endotelial dysfunction

Autor: T. A. Denisyuk, M. V. Pokrovsky, G. A. Lazareva, T. G. Pokrovskaya, M. V. Korokin, O. A. Osipova, A. I. Lazarev, L. N. Sernov, S. A. Demchenko

Publikováno v: Кубанский научный медицинский вестник, Iss 1, Pp 30-34 (2016)

Using of the combined use of non-selective inhibitor of arginase L-norvaline with simvastatin, atorvastatin, rosuvastatin and rosuvastatin nanopartikulirovanny on background modeling endotoxin-induced disease, the introduction of strain 603 Staphyloc

Externí odkaz: https://doaj.org/article/a0349a37d2be434a88ebed974ee9d8c4

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Proteome response to mistranslation

Autor: Močibob, Marko, Pranjić, Marija, Šemanjski Čurković, Maja, Spät, Philipp, Maček, Boris, Gruić-Sovulj, Ita

Mistranslation is an error in protein biosynthesis caused by erroneus incorporation of the amino acids. Aminoacyl-tRNA synthetases (aaRS) play the crucial role in this process, as they supply the ribosome with its substrates, aminoacylated tRNAs (aa-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::6f17bf0d03e7d2e5a22351e78381926f
https://www.bib.irb.hr/1278633

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Norvaline in natural products, peptides and proteins

Autor: Škibola, Zara

Neobične (ili rijetko korištene) aminokiseline su prisutne u nekolicini staničnih peptida. Često su uključene u peptidne antibiotike proizvedene ne-ribosomalnom sintezom, a u drugim slučajevima do njihove ribosomalne ugradnje dolazi prilikom ek

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3908::8e63ca16c25e7400dbcc9145ce087a63
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:8672

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Utjecaj mistranslacije na stabilnost modelnih proteina u staničnom ekstraktu

Autor: Brkić, Alojzije

Izoleucil-tRNA-sintetaza (IleRS) katalizira sintezu Ile-tRNAIle u procesu biosinteze proteina. IleRS može ponekad griješiti i misacilirati tRNAIle s valinom ili neproteinogenim norvalinom. Pogreška u biosintezi proteina (mistranslacija) može biti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f1898a713db16fc4cb2a2e566bb49554
https://www.bib.irb.hr/1099120

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Elongacijski faktor Tu kao potencijalni marker mistranslacijskog stresa u bakteriji Escherichia coli

Autor: Hloušek-Kasun, Andrea

Aminoacil-tRNA-sintetaze (aaRS) su enzimi koji kovalentno povezuju odgovarajuću molekulu tRNA s njoj pripadnom aminokiselinom u reakciji aminoaciliranja. Nastala aminoacilirana tRNA se pomoću elongacijskog faktora Tu (EF-Tu) doprema do ribosoma gdj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::798ee99638de921665565ac57963db44
https://www.bib.irb.hr/922776

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Mechanism of discrimination of natural proteinogenic and nonproteinogenic amino acids in class IA aminoacyl-tRNA synthetases

Autor: Biluš, Mirna

Aminoacil-tRNA-sintetaze kataliziraju vezanje aminokiselina na 3'-kraj tRNA u reakciji koja se sastoji od dva koraka: prvo dolazi do aktivacije aminokiseline uz pomoć ATP-a pa nastaje aminoacil-adenilat, a zatim do prijenosa aktivirane aminokiseline

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3908::ba78e4717dc9f300920343aa160783a3
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:134

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PHARMACOLOGICAL EFFICIENCY OF STATINS AND L-NORVALIN AT AN ENDOTOXIN-INDUCED ENDOTHELIAL DYSFUNCTION

Autor: A.L. Loktionov, M.V. Korokin, I.L. Ivlitskaya

Publikováno v: Research Results in Pharmacology 2(2): 25-35
Research Results in Pharmacology, Vol 2, Iss 2, Pp 25-35 (2016)

In the animals with endotoxin-induced endothelial dysfunction there were imbalance of contractile response of vessels wall observes when carrying out functional tests, increase of coefficient of endothelial dysfunction, decrease in contractility of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90275ddd7d8d0794e3b4b38ed1728386
https://doi.org/10.18413/2313-8971-2016-2-2-25-35

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Mehanizam diskriminacije prirodnih proteinogenih i neproteinogenih nepripadnih aminokiselina kod aminoacil-trna-sintetaza razreda IA

Autor: Biluš, Mirna

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::6c769eb62fd68ff6fa07fff60d88783a
https://www.bib.irb.hr/922796

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Proofreading activities of leucyl-tRNA synthetase prevent noncanonical mistranslation of the Escherichia coli proteome

Autor: Cvetešić, Nevena

Sažetak Aminoacil-tRNA-sintetaze (aaRS) su enzimi koji kataliziraju povezivanje aminokiseline i tRNA. Povezivanje isključivo pripadnog para presudno je za točnu biosintezu proteina. AaRS koje nisu dovoljno specifične za pripadnu aminokiselinu ima

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3908::b1160222ede3fe3e321b3bc3cfe4e14d
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:167

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