Zobrazeno 1 - 10
of 47
pro vyhledávání: '"nortopsentin analogues"'
Autor:
Daniela Carbone, Michele De Franco, Camilla Pecoraro, Davide Bassani, Matteo Pavan, Stella Cascioferro, Barbara Parrino, Girolamo Cirrincione, Stefano Dall’Acqua, Stefania Sut, Stefano Moro, Valentina Gandin, Patrizia Diana
Publikováno v:
Marine Drugs, Vol 21, Iss 5, p 288 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is one of the main aggressive types of cancer, characterized by late prognosis and drug resistance. Among the main factors sustaining PDAC progression, the alteration of cell metabolism has emerged to have a ke
Externí odkaz:
https://doaj.org/article/459f75d902884714a80923606fbf5a77
Publikováno v:
Arkivoc. 2022:30-42
A new series of thiazole nortopsentin analogues with a 5-azaindole moiety was conveniently synthesized in good to excellent yields by an Hantzsch reaction between thioamides and α-bromoacetyl compounds. The cytotoxic activity of the new derivatives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f1d4ca9f8b7d168927797b6eed19b7
https://doi.org/10.24820/ark.5550190.p011.640
https://doi.org/10.24820/ark.5550190.p011.640
Autor:
Barbara Parrino, Anna Carbone, Gloria Di Vita, Cristina Ciancimino, Alessandro Attanzio, Virginia Spanò, Alessandra Montalbano, Paola Barraja, Luisa Tesoriere, Maria Antonia Livrea, Patrizia Diana, Girolamo Cirrincione
Publikováno v:
Marine Drugs, Vol 13, Iss 4, Pp 1901-1924 (2015)
A new series of nortopsentin analogues, in which the imidazole ring of the natural product was replaced by thiazole and the indole unit bound to position 2 of the thiazole ring was substituted by a 7-azaindole moiety, was efficiently synthesized. Two
Externí odkaz:
https://doaj.org/article/8d75a9ae9c604ffd94446f6f7c2fe963
Akademický článek
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Autor:
Gerhard Kelter, Armin Maier, Patrizia Diana, Girolamo Cirrincione, Virginia Spanò, Paola Barraja, Barbara Parrino, Anna Carbone, Heinz-Herbert Fiebig
Publikováno v:
Marine Drugs, Vol 11, Iss 3, Pp 643-654 (2013)
2,5-bis(3′-Indolyl)pyrroles, analogues of the marine alkaloid nortopsentin, were conveniently prepared through a three step procedure in good overall yields. Derivatives 1a and 1b exhibited concentration-dependent antitumor activity towards a panel
Externí odkaz:
https://doaj.org/article/f3dd1038506f4ec08099288a9432a97a
Autor:
Daniela Carbone, Vincenzo Vestuto, Maria Rosalia Ferraro, Tania Ciaglia, Camilla Pecoraro, Eduardo Sommella, Stella Cascioferro, Emanuela Salviati, Sara Novi, Mario Felice Tecce, Giuseppina Amodio, Nunzio Iraci, Girolamo Cirrincione, Pietro Campiglia, Patrizia Diana, Alessia Bertamino, Barbara Parrino, Carmine Ostacolo
The enzyme glutaminase-1 (GLS-1) has shown a clear and coherent implication in the progression and exacerbation of different aggressive tumors such as glioblastoma, hepatocarcinoma, pancreas, bone, and triple-negative breast cancer. Few chemotypes ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1433badae9fa6eb1ab0ef56bbed5ccae
http://hdl.handle.net/10447/541084
http://hdl.handle.net/10447/541084
Autor:
Anna Carbone, Barbara Parrino, Maria Grazia Cusimano, Virginia Spanò, Alessandra Montalbano, Paola Barraja, Domenico Schillaci, Girolamo Cirrincione, Patrizia Diana, Stella Cascioferro
Publikováno v:
Marine Drugs, Vol 16, Iss 8, p 274 (2018)
New thiazole nortopsentin analogues were conveniently synthesized and evaluated for their activity as inhibitors of biofilm formation of relevant Gram-positive and Gram-negative pathogens. All compounds were able to interfere with the first step of b
Externí odkaz:
https://doaj.org/article/47bd3dadb5b74cf68b3720dcebe8e9ed
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Girolamo Cirrincione, Maria Grazia Cusimano, Stella Cascioferro, Alessandra Montalbano, Paola Barraja, Anna Carbone, Domenico Schillaci, Patrizia Diana, Virginia Spanò, Barbara Parrino
Publikováno v:
Marine Drugs
Marine Drugs, Vol 16, Iss 8, p 274 (2018)
Volume 16
Issue 8
Marine Drugs, Vol 16, Iss 8, p 274 (2018)
Volume 16
Issue 8
New thiazole nortopsentin analogues were conveniently synthesized and evaluated for their activity as inhibitors of biofilm formation of relevant Gram-positive and Gram-negative pathogens. All compounds were able to interfere with the first step of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3804f73d430cd95d350a2d58148d5236
https://pubmed.ncbi.nlm.nih.gov/30081568
https://pubmed.ncbi.nlm.nih.gov/30081568