Zobrazeno 1 - 10
of 330
pro vyhledávání: '"normal tissue sparing"'
Autor:
Jae Sik Kim, Hak Jae Kim
Publikováno v:
The Ewha Medical Journal, Vol 47, Iss 4 (2024)
FLASH radiotherapy (FLASH-RT) is an innovative approach that delivers ultra-high dose rates exceeding 40 Gy in less than a second, aiming to widen the therapeutic window by minimizing damage to normal tissue while maintaining tumor control. This r
Externí odkaz:
https://doaj.org/article/bf97f2d671874d678cc175eaf47fc88c
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionSpatially Fractionated Radiation Therapy (SFRT) is an unconventional therapeutic approach with the potential to disrupt the classical paradigms of conventional radiation therapy. The high spatial dose modulation in SFRT is believed to act
Externí odkaz:
https://doaj.org/article/bb98b691aee449189aa247f102a52e6c
Autor:
Line Kristensen, Per Rugaard Poulsen, Eleni Kanouta, Sky Rohrer, Christina Ankjærgaard, Claus E. Andersen, Jacob G. Johansen, Yuri Simeonov, Uli Weber, Cai Grau, Brita Singers Sørensen
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveA favorable effect of ultra-high dose rate (FLASH) radiation on normal tissue-sparing has been indicated in several preclinical studies. In these studies, the adverse effects of radiation damage were reduced without compromising tumor contro
Externí odkaz:
https://doaj.org/article/1155c1a758754caaae03cef9d22c69bf
Publikováno v:
Frontiers in Physics, Vol 12 (2024)
Radiation therapy, one of the most effective methods for cancer treatment, is still limited by the tolerances of normal tissues surrounding the tumor. Innovative techniques like spatially fractionated radiation therapy (SFRT) have been shown to incre
Externí odkaz:
https://doaj.org/article/b18aaaeb3552470bbddd71bebe1ae4ee
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
FLASH radiotherapy (FLASH-RT) is a novel radiotherapy approach based on the use of ultra-high dose radiation to treat malignant cells. Although tumours can be reduced or eradicated using radiotherapy, toxicities induced by radiation can compromise he
Externí odkaz:
https://doaj.org/article/0585363bc77d42d6aa831d7f7bebcae3
Autor:
Alexander Baikalov, Ramin Abolfath, Emil Schüler, Radhe Mohan, Jan J. Wilkens, Stefan Bartzsch
Publikováno v:
Frontiers in Physics, Vol 11 (2023)
Background: The mechanism responsible for the FLASH effect remains undetermined yet critical to the clinical translation of FLASH radiotherapy. The potential role of intertrack interactions in the FLASH effect, arising from the high spatio-temporal c
Externí odkaz:
https://doaj.org/article/193600dd7ad04c4f85c768f64fcb748a
Publikováno v:
Asian Journal of Oncology, Vol 06, Iss 03, Pp 097-106 (2020)
Proton beam therapy (PBT), because of its unique physics of no–exit dose deposition in the tissue, is an exciting prospect. The phenomenon of Bragg peak allows protons to deposit their almost entire energy towards the end of the path of the proton
Externí odkaz:
https://doaj.org/article/fcea54d596994ff69f7cd71d17aa80c7
Publikováno v:
Physical and Engineering Sciences in Medicine. 46:529-560
Particle therapies are becoming increasingly available clinically due to their beneficial energy deposition profile, sparing healthy tissues. This may be further promoted with ultra-high dose rates, termed FLASH. This review comprehensively summarise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e2a7bebc75cd0cc33a218f0ef30157
https://doi.org/10.1007/s13246-023-01266-z
https://doi.org/10.1007/s13246-023-01266-z
Autor:
Stefania Clemente, Caterina Oliviero, Giuseppe Palma, Vittoria D’Avino, Raffaele Liuzzi, Manuel Conson, Roberto Pacelli, Laura Cella
Publikováno v:
Radiation Oncology, Vol 13, Iss 1, Pp 1-10 (2018)
Abstract Background Technological advances in Hodgkin lymphoma (HL) radiation therapy (RT) by high conformal treatments potentially increase control over organs-at-risk (OARs) dose distribution. However, plan optimization remains a time-consuming tas
Externí odkaz:
https://doaj.org/article/e9ffb1c833eb4801938e500dbffdb971
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