Zobrazeno 1 - 10
of 6 097
pro vyhledávání: '"nonsynonymous"'
Autor:
Kassen, Rees, author
Publikováno v:
Experimental Evolution and the Nature of Biodiversity, 2024, ill.
Externí odkaz:
https://doi.org/10.1093/oso/9780192898661.003.0005
Autor:
Haesu Ko, J. Alex Pasternak, Margaret K. Mulligan, Glenn Hamonic, Naresh Ramesh, Daniel J. MacPhee, Graham S. Plastow, John C. S. Harding
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-16 (2024)
Abstract Background Porcine reproductive and respiratory syndrome virus 2 (PRRSV-2) infection during late gestation substantially lowers fetal viability and survival. In a previous genome-wide association study, a single nucleotide polymorphism on ch
Externí odkaz:
https://doaj.org/article/58c5c4b33127490a98036b3ecad2030e
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Selective constraint, the depletion of variation due to negative selection, provides insights into the functional impact of variants and disease mechanisms. However, its characterization in mice, the most commonly used mammalian m
Externí odkaz:
https://doaj.org/article/762c9a38a2e246febb013a106ca51c6c
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Background C-to-U RNA editing in plants is believed to confer its evolutionary adaptiveness by reversing unfavorable DNA mutations. This “restorative hypothesis” has not yet been tested genome-wide. In contrast, A-to-I RNA editing in ins
Externí odkaz:
https://doaj.org/article/ca1601df87944ad49c658aedc6f6f9b5
Autor:
Amit K. Maiti
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6306 (2024)
An estimation of the proportion of nonsynonymous to synonymous mutation (dn/ds, ω) of the SARS-CoV-2 genome would indicate the evolutionary dynamics necessary to evolve into novel strains with increased infection, virulence, and vaccine neutralizati
Externí odkaz:
https://doaj.org/article/b6581fb6c98d4ad98c03ca3bd7c9b92e
Autor:
Khyber Shinwari, Yurong Wu, Hafiz Muzzammel Rehman, Ningkun Xiao, Mikhail Bolkov, Irina Tuzankina, Valery Chereshnev
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-33 (2023)
Abstract Hennekam Lymphangiectasia–Lymphedema Syndrome 3 (HKLLS3) is a rare genetical disorder caused by mutations in a few genes including ADAMTS3. It is characterized by lymphatic dysplasia, intestinal lymphangiectasia, severe lymphedema and dist
Externí odkaz:
https://doaj.org/article/cca1666d1f0248af8f9090e07ba440af
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Kinesin family member 5A (KIF5A) is a motor neuron protein expressed in neurons and involved in anterograde transportation of organelles, proteins, and RNA. Variations in the KIF5A gene that interfere with axonal transport have emerged
Externí odkaz:
https://doaj.org/article/9763f1c8fa7d4214a8c7a7f0cdc24a8c
Publikováno v:
Clinical Epidemiology and Global Health, Vol 24, Iss , Pp 101407- (2023)
Problem considered: Typhoid fever caused by Salmonella enterica serovar Typhi (Salmonella Typhi) strains with multi-drug resistance (MDR) has become a significant global threat, as existing therapeutic options are limited. To combat this issue, effic
Externí odkaz:
https://doaj.org/article/be5d416076b74ccf8c78ff78d78410d5
Autor:
Alan Le Moan, Marina Panova, Aurélien De Jode, Olga Ortega‐Martinez, Mårten Duvetorp, Rui Faria, Roger Butlin, Kerstin Johannesson
Publikováno v:
Evolutionary Applications, Vol 16, Iss 2, Pp 279-292 (2023)
Abstract Understanding the genetic targets of natural selection is one of the most challenging goals of population genetics. Some of the earliest candidate genes were identified from associations between allozyme allele frequencies and environmental
Externí odkaz:
https://doaj.org/article/4352c7ffe9d349a9bbc9caf806da9ebc
Autor:
Sanjaykumar Tikute, Pratik Deshmukh, Nutan Chavan, Anita Shete, Pooja Shinde, Pragya Yadav, Mallika Lavania
Publikováno v:
Microorganisms, Vol 12, Iss 3, p 490 (2024)
Coxsackievirus-A6 (CV-A6) is responsible for more severe dermatological manifestations compared to other enteroviruses such as CV-A10, CV-A16, and EV-A71, causing HFMD in children and adults. Between 2005 and 2007, the recombinant subclade D3/RF-A st
Externí odkaz:
https://doaj.org/article/b53f27a6bda34359b9c05338bba7e732