Zobrazeno 1 - 10
of 110 903
pro vyhledávání: '"non-small cell lung cancer"'
Autor:
Zheng Lei, Jiang He, Haonan Yang, Lu Zhang, Tangmin Lai, Liu Zhou, Zheng Tang, Jiangdong Sui, Yongzhong Wu
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Radioresistance contributes to metastasis and recurrence in non-small cell lung cancer (NSCLC) patients. However, the underlying mechanism remains unclear. To provide novel clues, a complete multi-omics map of a radioresistant cancer cell li
Externí odkaz:
https://doaj.org/article/584f8fe95f594d409c38f32756372d43
Autor:
Shanshan Huang, Yaling Long, Yuan Gao, Wanling Lin, Lei Wang, Jizong Jiang, Xun Yuan, Yuan Chen, Peng Zhang, Qian Chu
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-14 (2024)
Abstract Background Aberrant activation of mesenchymal epithelial transition (MET) has been considered to mediate primary and acquired resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in EGFR-mutant non-small ce
Externí odkaz:
https://doaj.org/article/072706ab2ba84703ae0b7712ea79cc75
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract This systematic review and network meta-analysis evaluates first-line treatment options for patients with EGFR-mutant non-small cell lung cancer (NSCLC) and brain metastases. We analyzed 24 randomized controlled trials (RCTs) involving 2,682
Externí odkaz:
https://doaj.org/article/8ebe442c00564a6bbb358712a3a844c2
Autor:
Yaping Hong, Wu Zhuang, Jinhuo Lai, Haipeng Xu, Yueming He, Jinlan Lin, Qin Shi, Shengjia Chen, Zhangzhou Huang, Shijie Chen, Dongzhu Lu, Gen Lin, Yunjian Huang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Plasma epidermal growth factor receptor mutation (EGFRm) circulating tumor DNA (ctDNA) dynamics exhibit promise in predicting outcomes in patients with EGFRm-advanced non-small cell lung cancer (NSCLC). However, there remains limited trial-l
Externí odkaz:
https://doaj.org/article/15d99de768db44beba5ec8321e298a39
Autor:
Bingqing Yue, Dian Xiong, Juan Chen, Xiucheng Yang, Jin Zhao, Jingbo Shao, Dong Wei, Fei Gao, Man Huang, Jingyu Chen
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background The prevalence of non-small cell lung cancer (NSCLC) is notably elevated in individuals diagnosed with idiopathic pulmonary fibrosis (IPF). Secreted phosphoprotein 1 (SPP1), known for its involvement in diverse physiological proce
Externí odkaz:
https://doaj.org/article/6f8991a7db0748a581301659dc6950b9
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-6 (2024)
Abstract This case report details the successful treatment of a 68-year-old male patient with locally advanced RET-rearranged lung adenocarcinoma using neoadjuvant pralsetinib. The patient initially presented with a suspicious right upper lobe nodule
Externí odkaz:
https://doaj.org/article/637b3f31a86245ada09565dd2f0bd1b7
Autor:
Jiafang Xu, Qingjie Hu, Yu Liu, Chaoqun Wang, Siqi Yin, Huifang He, Hai Li, Ruiqi Yang, Meizi Song
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-6 (2024)
Abstract Stage I non-small cell lung cancer (NSCLC) accounts for about 15% of incident cancer cases. Prognosis is poor, with a metastasis and recurrence rate of 38% within 2 years of surgery and an overall 5-year survival rate of 54–60%. Here, we r
Externí odkaz:
https://doaj.org/article/353dc0c855c74092aa726be5ab79b389
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 4507-4517 (2024)
Yawan Jing,1,2 Ruixin Cheng,3 Hao Zeng,1 Qin Huang,1 Dongyu He,1 Jiayi Sun,1 Panwen Tian,1,4 Yalun Li1,4 1Department of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Respiratory Heal
Externí odkaz:
https://doaj.org/article/61874a4feed143d3bb42c30cd01c1643
Autor:
Saeko Kashimura, Miki Sato, Takahito Inagaki, Masaoki Kin, Ryo Manabe, Sojiro Kusumoto, Atsushi Horiike, Takuya Tsunoda, Mari Kogo
Publikováno v:
Thoracic Cancer, Vol 15, Iss 28, Pp 2049-2060 (2024)
Abstract Background The relationship between the combination of platelet count and neutrophil‐lymphocyte ratio (COP‐NLR) and prognosis in patients with advanced non‐small cell lung cancer (NSCLC) treated with immune checkpoint inhibitor (ICI) c
Externí odkaz:
https://doaj.org/article/fcaaca174d4f4c25a101f80f1ed991cb
Autor:
Xixi Zheng, Lili Zhou, Hui Shi, Juan An, Weiran Xu, Xiaosheng Ding, Yichun Hua, Weiwei Shi, Xiaoyan Li
Publikováno v:
Thoracic Cancer, Vol 15, Iss 28, Pp 2029-2037 (2024)
Abstract Background Patients with programmed cell death‐ligand 1 (PD‐L1) ≥50% metastatic non‐small cell lung cancer (NSCLC) treated with first‐line immunotherapy showed heterogeneous tumor responses. In this study, we investigated the clini
Externí odkaz:
https://doaj.org/article/eaa72eb92bbc46599c34cc893044f50d