Zobrazeno 1 - 10
of 1 349
pro vyhledávání: '"non-genetic"'
Autor:
Anneza Yiallourou, Katerina Pantavou, Georgios Markozannes, Antonis Pilavas, Andrea Georgiou, Andria Hadjikou, Mary Economou, Neophytos Christodoulou, Konstantinos Letsos, Elina Khattab, Chrystalleni Kossyva, Maria Constantinou, Melanie Theodoridou, Daniele Piovani, Konstantinos Κ. Tsilidis, Stefanos Bonovas, Georgios K. Nikolopoulos
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-23 (2024)
Abstract Background Previous research has found associations between various non-genetic factors and breast cancer (BrCa) risk. This study summarises and appraises the credibility of the available evidence on the association between non-genetic facto
Externí odkaz:
https://doaj.org/article/9282958dae1c46f1a4afc59cf11f27b8
Autor:
Majid Momeny, Mari Tienhaara, Mukund Sharma, Deepankar Chakroborty, Roosa Varjus, Iina Takala, Joni Merisaari, Artur Padzik, Andreas Vogt, Ilkka Paatero, Klaus Elenius, Teemu D Laajala, Kari J Kurppa, Jukka Westermarck
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 7, Pp 1603-1629 (2024)
Abstract Despite clinical benefits of tyrosine kinase inhibitors (TKIs) in cancer, most tumors can reactivate proliferation under TKI therapy. Here we present transcriptional profiling of HER2+ breast cancer cells transitioning from dormant drug tole
Externí odkaz:
https://doaj.org/article/709f9a596c0c46e4951cbcebf8781895
Publikováno v:
Translational Oncology, Vol 47, Iss , Pp 102055- (2024)
Breast cancer (BC) is a complex and multifactorial disease, driven by genetic alterations that promote tumor growth and progression. However, recent research has highlighted the importance of non-genetic factors in shaping cancer evolution and influe
Externí odkaz:
https://doaj.org/article/f2a2feba4044479282573d69f7578d68
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116956- (2024)
The fading efficacy of antibiotics is a growing global health concern due to its life-threatening consequences and increased healthcare costs. Non-genetic mechanisms of antimicrobial resistance, such as those employed by Chlamydia pneumoniae and Chla
Externí odkaz:
https://doaj.org/article/c687804fc467458db5519a67173df231
Autor:
Haifeng Wang, Shanning Jin, Zhenfei Xu, Jinxia Zhang, Xuejiao An, Rui Zhang, Yanyan Hao, Lina Zhu, Yinchun Wang, Junni Jin, Zhiguang Geng, Chenglan Li, Jianye Li, Yaojing Yue
Publikováno v:
Animal Biotechnology, Vol 35, Iss 1 (2024)
The aim of this study was to analyze the effects of non-genetic factors on the estimation of genetic parameters of early growth traits in hybrid mutton sheep using ASReml software, in order to provide theoretical basis for screening the optimal hybri
Externí odkaz:
https://doaj.org/article/049e72abdfdd443683b75f585f30e85f
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with a five-year survival rate of approximately 10%. Genetic mutations are pivotal drivers in PDAC pathogenesis, but recent investigations also revealed the involvemen
Externí odkaz:
https://doaj.org/article/927acce8ec20446b995637bd64f2a524
Autor:
Wenna Liu, Qingwei Lu, Sen Tang, Xue Pu, Yaqian Wang, Cuiling Wu, Xiangrong Hu, Wei Hong, Xuefeng Fu
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
As the economic level of individuals rises, so too does the demand for mutton. Enhancing the breeds of mutton sheep not only boosts production efficiency and economic benefits but also fosters the sustainable growth of the mutton sheep breeding indus
Externí odkaz:
https://doaj.org/article/50830fd4a1fe4ac9b98e1d3effe70500
Autor:
Günter A. Müller, Timo D. Müller
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Glycosylphosphatidylinositol-anchored proteins (GPI-APs) are anchored at the outer phospholipid layer of eukaryotic plasma membranes exclusively by a glycolipid. GPI-APs are not only released into extracellular compartments by lipolytic cleavage. In
Externí odkaz:
https://doaj.org/article/87c6be6d0ac1406f88322152bee9c541
Autor:
Abdulmajeed M. Jali, David Banji, Otilia J. F. Banji, Khalid Y. Hurubi, Faisal Y. Tawhari, Atheer A. Alameer, Atyaf S. Dohal, Raha A. Zanqoti
Publikováno v:
Pharmaceuticals, Vol 17, Iss 8, p 1010 (2024)
Peripheral neuropathy (PN) is a multifaceted disorder characterised by peripheral nerve damage, manifesting in symptoms like pain, weakness, and autonomic dysfunction. This review assesses preclinical models in PN research, evaluating their relevance
Externí odkaz:
https://doaj.org/article/9273f52052c14a099aa02bff56a7b6a9
Autor:
Yue Shi, Yunpeng Qi, Yan Liu, Youjun Rong, Xiaofang Ao, Mingzhu Zhang, Qincheng Xia, Yanjun Zhang, Ruijun Wang
Publikováno v:
Veterinary Sciences, Vol 11, Iss 7, p 308 (2024)
The purpose of this study was to investigate the effects of non-genetic factors on the growth and development performance of Inner Mongolia white cashmere goats (Erlanghan type), such as birth weight (BW), weaning weight (WW), 6-month weight (6 WT),
Externí odkaz:
https://doaj.org/article/07c3045f1b7748fea9aa9e3a03a711d1